OrthoEvidence - Search

General Orthopaedics
Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Tramadol Consumption After Arthroscopic Shoulder Surgery: A Prospective, Randomized, Double-blind Clinical Trial.
Medeni Med J. 2023 01-Sep;():. 10.4274/MMJ.galenos.2023.99975

Trauma
Comparing the efficacy of intravenous morphine versus ibuprofen or the combination of ibuprofen and acetaminophen in patients with closed limb fractures: a randomized clinical trial.
BMC Emerg Med. 2024 01-Jan;():. 10.1186/s12873-024-00933-y

Foot & Ankle
Comparison of intravenous ibuprofen and tenoxicam efficiency in ankle injury: a randomized, double-blind study.
Ir J Med Sci. 2023 01-Aug;():. 10.1007/s11845-022-03159-8

Arthroplasty
The Use of Combination Paracetamol and Ibuprofen in Postoperative Pain after Total Knee Arthroplasty, a Randomized Controlled Trial.
Pain Physician. 2021 01-Dec;():.

Pediatric Orthopaedics
Efficacy and safety of ibuprofen in children with musculoskeletal injuries: A systematic review and meta-analysis of randomized controlled trials.
Medicine. 2021 01-Jul;():. 10.1097/MD.0000000000026516

General Orthopaedics
A randomized controlled trial of oxycodone/acetaminophen versus acetaminophen alone for emergency department patients with musculoskeletal pain refractory to ibuprofen.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 2021 21-Aug;():. 10.1111/acem.14231.

Trauma
Intravenous Ibuprofen Reduces Opioid Consumption in Acute Pain Management for Orthopaedic Trauma Patients

Arthroplasty

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial
JAMA. 2019 Feb 12;321(6):562-571. doi: 10.1001/jama.2018.22039.

Hand & Wrist
Pain Management After Carpal Tunnel Release Surgery: A Prospective Randomized Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone

This report has been verified by one or more authors of the original publication.

J Hand Surg Am. 2018 Oct;43(10):913-919. doi: 10.1016/j.jhsa.2018.08.011

Hand & Wrist
Fighting the Opioid Epidemic: A Prospective Randomized Controlled Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone after Hand Surgery

Hand & Wrist
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen verses Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures

Arthroplasty
A Randomized Trial Comparing the Safety and Efficacy of Intravenous Ibuprofen versus Ibuprofen and Acetaminophen in Knee or Hip Arthroplasty

This report has been verified by one or more authors of the original publication.

Pain Physician. 2016 Jul;19(6):349-56

Pediatric Orthopaedics
Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial

This report has been verified by one or more authors of the original publication.

CMAJ. 2014 Dec 9;186(18):1358-63

General Orthopaedics
A randomized placebo-controlled trial comparing the efficacy of etoricoxib 30 mg and ibuprofen 2400 mg for the treatment of patients with osteoarthritis
Osteoarthritis Cartilage. 2007 Dec;15(12):1348-56. Epub 2007 Jul 16

Arthroplasty
Celecoxib versus ibuprofen in the prevention of heterotopic ossification following total hip replacement: A PROSPECTIVE RANDOMISED TRIAL
J Bone Joint Surg Br. 2007 Feb;89(2):155-9.

Osteoarthritis
Glucosamine but not ibuprofen alters cartilage turnover in osteoarthritis patients in response to physical training
Osteoarthritis Cartilage. 2010 Jan;18(1):34-40. Epub 2009 Jul 15

Osteoarthritis

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Advice to use topical or oral ibuprofen for chronic knee pain in older people: Randomized controlled trial and patient preference study
BMJ. 2008 Jan 19;336(7636):138-42. Epub 2007 Dec 4.