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You are viewing the most viewed ACE Reports by Sports Medicine Specialists over the last 30 days in all specialties.
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①
Synopsis:
64 patients with primary frozen shoulder (adhesive capsulitis) were randomized to receive either a multisite (rotator interval, intraarticular, and subacromial bursa) triamcinolone injection (MCI; n=32) or a single-site triamcinolone injection (SRI; n=32).The primary outcomes of interest include range of motion in shoulder flexion, abduction, external and internal rotation and pain on a Visual Analog Scale (VAS).Secondary outcomes included patient satisfaction, American Shoudler and Elbow Surgeons (ASES) scores, Contant-Murley Score (CMS), and the incidence of palpitations.Range of motion in flexion, abduction, internal rotation at 8 weeks, ASES scores, CMS scores, and VAS pain at 4 & 8 weeks were all significantly better in the MCI group compared to the SRI group. All other outcomes...
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Level 1 RCT
①
Synopsis:
One hundred and seventy-seven patients with chronic knee pain from knee osteoarthritis (OA) were randomized to receive cooled radiofrequency ablation (CRFA; n=89) of the genicular nerves or a single intra-articular hyaluronic acid (HA; n=88).The primary outcome of interest was the number of patients who reported a =>50% reduction in pain scores from baseline after 6 months.Additional outcomes of interest included pain scores on a Numeric Rating Scale (NRS), the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index, WOMAC pain scores, WOMAC physical function scores, WOMAC stiffness scores, patient perception of treatment effect as reflected by the Global Perceived Effect (GPE) score, the Euro-Qol-5 Dimensions-5 Level (EQ-5D-5L) quality of life questionnaire, and the incidence of treatment-related and non-treatment related adverse events.Outcomes were assessed at 1, 3, and 6 months post-treatment.Results revealed a statistically significantly higher proportion of patients in the CRFA group who reported =>50% improvement in pain scores from baseline compared to the HA group (71% vs.38%, p<0.0001).NRS pain scores, WOMAC total scores, WOMAC pain scores WOMAC physical function scores, GPE scores, and EQ-5D-5L scores were statistically significantly in favour of the CRFA group at all time points compared to the HA group (p<0.05 for all).WOMAC stiffness scores were statistically significantly in favour of the CRFA group at 3 months (p=0.0022) and 6 months (p<0.0001) post-treatment. The incidence of...
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Author verified Level 1 RCT
②
Synopsis:
58 patients were randomized to undergo either a heave slow resistance (HSR) protocol or an eccentric training (ECC) intervention as treatment for mid-portion Achilles tendinopathy.The study was conducted in order to compare the efficacy of HSR with that of ECC as an intervention for this condition.The study found that the two regimens were comparable in pain and function scores, tendon thickness, and patient satisfaction. However, results may...
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Author verified Level 2 RCT
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Synopsis:
One hundred and forty-six patients 35–65 years of age with knee symptoms consistent with a degenerative medial meniscus tear were randomized into receiving arthroscopic partial meniscectomy (APM) or a sham surgery (diagnostic knee arthroscopy).Primary outcomes of interest included radiographic knee osteoarthritis through using the Kellgren and Lawrence knee osteoarthritis grading and the Osteoarthritis Research Society International (OARSI) instrument, as well as patient-related outcomes via the Western Ontario Meniscal Evaluation Tool (WOMET), the Lysholm knee score, and knee pain after exercise.Outcomes of interest were assessed 5 years post-operation.No significant differences between the APM and placebo groups were observed in all three patient-relevant outcomes, 5 years post-operation.A slight increase in the risk of radiographic knee osteoarthritis progression was observed in the APM group, however this was not significantly different.A significantly higher risk of mechanical symptoms was observed in the APM group. Otherwise, outcome comparisons...
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Author verified Level 1 RCT
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Synopsis:
12,211 patients from 21 trauma centers in the United States and Canada were included in this non-inferiority randomized trial comparing aspirin (n=6,101) and low molecular-weight heparin (n=6110).The primary outcome of interest was death by any cause at 90 days.Secondary outcomes of interest included the risk of thromboembolic events (pulmonary embolism; deep-vein thrombosis), cause-specific death, bleeding & wound complications, and the rate of infection.Aspirin was found to be non-inferior to low molecular-weight heparin with respect to the primary outcome of death by any cause. No differences in...
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Level 1 RCT
①
Synopsis:
94 patients between the ages of 50-75 years with knee osteoarthritis were included in this non inferiority trial in which patients were randomly allotted to undergo either traditional moxibustion (TM; n=44) or jade moxibustion (JM; n=45).The primary outcome of interest was quality of life, measured by the 8 dimensions of the 36-item short-form health survey (SF-36) at 8,12 and 24 weeks.Secondary outcomes of interest included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) knee stiffness scores at 2, 4, 8, 12, and 24 weeks, serum levels of osteoarthritis-related cytokines.Adverse events were also recorded.The results of the study indicate that JM significantly improved role-physical and physical functioning SF-36 scores at long-term follow-up compared to TM.WOMAC stiffness scores showed significant improvement from baseline for both groups, however no significant differences were found between groups.Serum COMP, MMP-13 and MCP-1 levels in the JM group and serum IL-1β, IL-2, IL-6, MMP-3 and IL-8 levels in the TM group fell significantly, although no significant differences were observed between groups. Rates of adverse...
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Author verified Level 1 RCT
Synopsis:
61 patients with idiopathic frozen shoulder were randomized to receive either watchful waiting (WW; n=31) or physical therapy (PT; n=30).The primary outcome of interest was the American Shoulder and Elbow Surgeons score (ASES) questionnaire.Secondary outcomes of interest included pain scores on a Visual Analog Scale (VAS), the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire, direct patient healthcare costs, and patient value (defined as the 12-month ASES score divided by healthcare costs).Outcomes were assessed at baseline, 6 weeks, and 3, 6, and 12 months.Both cohorts improved at each time point for all primary outcomes, but no significant differences in patient-reported outcomes (PROMs) between treatment modalities were found at any time point.WW patients incurred significantly lower direct costs than PT patients, with a normalized mean difference was of 1,635.67.Patients in the WW group also achieved greater patient value, with a normalized mean difference of -146.97. Both of these...
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Conference Report
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Synopsis:
Twenty-seven randomized controlled trials that compared the safety and efficacy of platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC), and hyaluronic acid (HA) were included in this meta-analysis.Outcomes of interest included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), pain on a Visual Analog Scale (VAS), International Knee Documentation Committee (IKDC), and Lequesne Index Score (LEQ).WOMAC, IKDC, and VAS scores favored PRP against HA.Similarly, in the network meta-analyses comparing BMAC and HA, WOMAC, IKDC, and VAS scores favored BMAC. No differences were...
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Author verified Level 1 Meta Analysis
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Synopsis:
84 patients over 18 years of age with isolated rib fractures were included in this single center, prospective, placebo controlled, double blind trial.Patients were randomly allocated to receive either 10% lidocaine spray (LS; n=29), etofenamate spray (ES; n=28) or placebo spray (PS; n=27).The primary outcome of interest was pain intensity measured using a numerical rating scale (NRS) at baseline, and 15, 30, 60 and 120 minutes.Other outcomes of interest included rescue medication requirements and adverse events.Study findings suggest that all three groups demonstrated similar NRS scores, with no significant difference in pain reduction found at any timepoint.The maximum reduction was seen in the LS group between baseline and 120 minutes, however this difference was not statistically significant.It was also seen that the need for rescue medication was lowest in the LS group; a difference that was found to be clinically significant but not statistically significant. Importantly, only one...
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Author verified Level 1 RCT
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Synopsis:
15 randomized controlled trials (988 patients) comparing ultrasound-guided acupotomy against a control were included in this systematic review and meta-analysis.Outcomes of interest included clinical effectiveness, pain on a Visual Analog Scale, Quinnell grade, and the incidence of recurrence and complications. All outcomes favored...
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Level 1 Meta Analysis