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20%
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7%
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100%
8%
Synopsis: One hundred twenty-eight patients with knee osteoarthritis were randomized to receive prolotherapy with 5% dextrose (n=30), 10% dextrose (n=30), 20% dextrose (n=30), or exercise plus hotpack only (n=30).All prolotherapy groups received three injection sessions at weeks 0, 3, and 6, combined with a home exercise program and hotpack therapy.The primary outcome was pain assessed by VAS.Secondary outcomes included WOMAC scores, knee range of motion, timed up and go (TUG) test, and SF-36 quality of life scores.Outcomes were measured at baseline, 6 weeks, and 12 weeks.Overall, results showed that 10% and 20% dextrose groups had significantly greater pain reduction and functional improvements compared with exercise alone, while 20% dextrose also improved knee flexion. The findings suggest... Read More »
Level 1 RCT
6%
Synopsis: Ninety-three patients with severe knee or hip osteoarthritis were randomized to receive either high-intensity interval training (HIIT; n=30), passive heat therapy (Heat; n=30), or home-based exercise (Home; n=33) as prehabilitation before total hip or knee arthroplasty.The primary outcome of interest was peak oxygen consumption (peak 𝑉𝑂2).Secondary outcomes included the anaerobic threshold, physical function measures, and subjective health assessments.Outcomes were assessed over a 12-week period.Overall, the results revealed that HIIT significantly improved peak 𝑉𝑂2V and the anaerobic threshold compared to the other groups.Heat therapy also increased the anaerobic threshold but not peak 𝑉𝑂2. These findings suggest... Read More »
Level 1 RCT
5%
Synopsis: 144 patients with primary complete Achilles tendon rupture were randomized to be treated with either a surgical repair and accelerated functional rehabilitation or with only the accelerated functional rehabilitation. Over the course of a two year follow up, it was observed that Achilles tendon rupture led to clinically similar results between the two treatment groups. Read More »
Level 2 RCT
5%
Synopsis: Forty-six patients who sustained an anterior cruciate ligament (ACL) tear and were scheduled for reconstruction were randomized into a group receiving either a blood flow restriction (BFR) therapy program (n=22) or a control group without BFR (n=24).The primary outcome of interest was isometric quadriceps strength at 3 months postoperatively, measured as peak and mean torques during seated leg extension exercises and presented as a ratio of the healthy limb.Secondary outcomes included patient-reported outcomes such as pain, knee function, and physical function, knee range of motion, quadriceps circumference and adverse effects.Outcomes were assessed up to 6 months postoperatively. Overall, the study... Read More »
Level 1 RCT
4%
Synopsis: 101 patients with an acute grade 1 or 2 ankle sprain were randomized to be managed with an early therapeutic exercise program or a conventional PRICE (protection, rest, ice, compression and elevation) protocol.It was observed that after early incorporating therapeutic exercises during the first week after an ankle sprain brings about significant improvements in physical activity and improved functional status compared to the standard treatment at weeks 1 and 2. At 16-week follow-up,... Read More »
Author verified Level 2 RCT
4%
Synopsis: 109 patients with degenerative knee cartilage were randomized to determine the efficacy of platelet-rich plasma (PRP) compared to viscosupplementation via hyaluronic acid (HA) as a treatment method.Patients were allocated to three injections of either solution, and were followed up for 12 months.Results revealed that there were no differences between groups in clinical outcome for the duration of the study. Interestingly, a sub-group... Read More »
Level 2 RCT
4%
Synopsis: Ninety patients with painful trapeziometacarpal osteoarthritis were randomized to receive a single intra-articular injection of platelet-rich plasma (n=45) or saline placebo (n=45).The primary outcome was change in pain on load (NRS 0–100) from baseline to 6 months.Secondary outcomes included change in pain on load at 3 months, pain at rest, Patient-Rated Wrist and Hand Evaluation (PRWHE) score, Disability of the Arm, Shoulder, and Hand (DASH) score, thumb range of motion, and pinch strength at 3 and 6 months.Overall, the results showed no significant difference in pain on load at 6 months between PRP and placebo, and no clinically relevant differences in secondary outcomes. The study concludes... Read More »
Level 1 RCT
3%
Synopsis: 59 patients (>18 years of age) who were diagnosed with mallet finger (with or without fracture) and who had undergone continuous splint/cast immobilization and hyper-extension intervention (6-8 weeks), were randomly assigned into 1 of 2 treatment groups to determine the effect of an additional one month of night splinting on extensor lag.Participants either received an additional one month intervention with a night splint following their continuous splinting period or received no additional intervention (control). Results from the... Read More »
Author verified Level 2 RCT
3%
Synopsis: Seventy patients with rotator cuff tendinopathy were randomized to receive therapeutic ultrasound (n=35) or low-level laser therapy (n=35), each combined with hot packs, TENS, and a structured home-based exercise program for 15 sessions over 3 weeks.The primary outcomes were pain (VAS), function (SPADI, CMS, DASH), and hand grip strength (HGS).Secondary outcomes included depression (BDI), anxiety (BAI), sleep quality (PSQI), and quality of life (SF-36).Assessments were performed at baseline, 1, 4, and 12 weeks.Overall, both groups showed significant improvements in all primary and secondary measures over time, with no between-group differences except for greater HGS improvement in the ultrasound group. These findings suggest... Read More »
Level 1 RCT
3%
Synopsis: Seventy patients with rotator cuff tears were randomized to receive either hyaluronic acid injection (n=35) or placebo (n=35) after arthroscopic rotator cuff repair.The primary outcome of interest was tendon integrity assessed by MRI using the Sugaya classification.Secondary outcomes included VAS pain scores, ASES, CONSTANT scores, range of motion, and strength.Outcomes were assessed at 2 weeks, 3 months, 6 months, and 12 months.Overall, the results of the study revealed that hyaluronic acid did not improve pain or functional scores compared with placebo but was associated with greater recovery of abduction, internal rotation, and external rotation at 6 and 12 months, and a lower re-tear rate on MRI (14.4% vs 26.7%). The findings suggest... Read More »
Conference Report