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6%
Synopsis: 186 patients with a severe lateral ankle sprain (type III) were randomized to treatment to 3 weeks of rigid immobilization with a walking boot followed by 3 weeks of immobilization with a functional brace, or to a functional brace for 6 weeks.The purpose was to compare these two conservative treatment methods for outcomes in pain, function, and ankle stability up to 12 weeks after the injury.AOFAS scores were better for the first 6 weeks in patients receiving the functional brace, and pain and comfort outcomes also benefited within the first few weeks from using a functional brace. By 12 weeks,... Read More »
Author verified Level 2 RCT
6%
Synopsis: 70 patients with chronic plantar fasciitis were randomized to receive a platelet-rich plasma (PRP) injection (n=35) or a corticosteroid injection (n=35).The primary outcome of interest was pain, as measured on a Visual Analog Scale (VAS) and the American Orthopaedic Foot and Ankle Society (AOFAS) score.Outcomes were assessed at 15 days, and 1, 3, and 6 months post-injection.The results revealed significantly lower VAS pain scores with PRP compared to corticosteroids at 1, 3 and 6 months, and significantly better AOFAS scores at 3 and 6 months.The results of this study suggest that PRP can provide longer-term pain control vs.corticosteroids, particularly in the 3-6 month range. However, the methodological... Read More »
Level 1 RCT
4%
Synopsis: 26 patients with patellofemoral pain syndrome were randomized to receive a 4-week program of instrument-assisted soft tissue mobilization (IASTM) plus blood flow restriction (BFR) training (n=13) or IASTM alone (n=13).The outcomes of interest included knee pain on a Visual Analog Scale (VAS), Lysholm knee scores, Modified Thomas test (MTT), and knee extensor strength, assessed after 1 treatment and upon completion of treatment.The combination group reported significantly greater pain scores after 1 treatment and after completion of treatment compared to the IASTM only group.However, Lysholm scores were higher in the control group after treatment. No differences in... Read More »
Level 1 RCT
3%
Synopsis: 80 patients undergoing a total hip arthroplasty were randomized to receive a pericapsular nerve group block (PENG; n=40) or local infiltration analgesia (LIA; n=40).The primary outcome of interest was pain scores at rest and during exercise on a Visual Analog Scale (VAS), measured during the first 48 hours post-operation, and post-operative morphine consumption.Secondary outcomes of interest included hip range of motion, daily mobilization, quadriceps strength, length of stay, and the rate of complications.The results showed no significant differences in VAS pain scores at rest or morphine consumption.Moreover, no differences in range of motion, daily mobilization, length of stay, and quadriceps strength during the first 2 days post-operation were observed.However, pain scores during exercise were significantly higher in the PENG group in the first 6 hours, suggesting inferior pain control with PENG vs. Read More »
Level 1 RCT
3%
Synopsis: Twenty-seven randomized controlled trials that compared the safety and efficacy of platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC), and hyaluronic acid (HA) were included in this meta-analysis.Outcomes of interest included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), pain on a Visual Analog Scale (VAS), International Knee Documentation Committee (IKDC), and Lequesne Index Score (LEQ).WOMAC, IKDC, and VAS scores favored PRP against HA.Similarly, in the network meta-analyses comparing BMAC and HA, WOMAC, IKDC, and VAS scores favored BMAC. No differences were... Read More »
Author verified Level 1 Meta Analysis
3%
Synopsis: 17 studies including a total of 1,190 patients were included in this systematic review and meta-analysis assessing the effectiveness of manipulation therapy for chronic neck pain.Outcomes of interest included pain intensity and neck disability (assessed with the Neck Disability Index [NDI]).The results of the meta-analysis found that manipulative therapy, with or without exercise, resulted in significantly lower pain intensity and disability than controls.There was no significant difference in the risk of adverse events between the two groups. The results of... Read More »
Level 1 Meta Analysis
3%
Synopsis: 91 patients with chronic low back pain were randomized to receive an 8-week cognitive functional therapy (CFT) program (n=45) or movement system impairment (MSI)-based treatment program (n=46).The primary outcome of interest was pain intensity, measured on a Numeric Rating Scale (NRS).The secondary outcomes of interest included disability, kinesiophobia, and gait kinetics measured via vertical ground reaction force (VGRF) parameters.Outcomes were assessed at 8 weeks and 6 months follow-up. The CFT group... Read More »
Level 1 RCT
3%
Synopsis: 30 patients with lateral epicondylitis unresponsive to conservative treatment were randomized to receive an injection of corticosteroid (n=15) or platelet-rich plasma (PRP; n=15).The primary outcomes of interest were pain measured on a Visual Analog Scale (VAS) and the Disability of the Arm, Shoulder, and Hand (DASH) score.Outcomes were measured 1 month after injection.The PRP group demonstrated significantly better improvement in both VAS pain scores and DASH scores compared to the corticosteroid group. Future studies with... Read More »
Level 1 RCT
2%
Synopsis: 101 patients with an acute Achilles tendon rupture were randomized to one of two groups: a surgical group, wherein surgical repair was performed and early weight-bearing was encouraged, or a non-surgical group, wherein patients were treated conservatively and early weight-bearing was also encouraged.The purpose of this study was to evaluate these two treatment methods with respect to functional outcomes. Results indicated that... Read More »
Level 2 RCT
2%
Synopsis: 96 patients with a displaced, intraarticular calcaneal fracture were randomized to either a percutaneous reduction and cannulated screw fixation or a minimally invasive sinus tarsi approach for plate and screw fixation.The purpose of this study was to compare functional and radiological outcomes between the two treatment options over a 24-month follow-up.American Orthopaedic Foot and Ankle Society scores overall did not significantly differ between groups, though the subscales of sagittal motion and hindfoot motion significantly favoured the percutaneous reduction and cannulated screw fixation group. With the exception... Read More »
Level 2 RCT