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7%
Synopsis: Eleven randomized controlled trials evaluating either leukocyte-rich platelet-rich plasma (LR-PRP) or leukocyte-poor platelet-rich plasma (LR-PRP) compared to control injections in patients with lateral epicondylitis.The outcomes of interest were pain scores and clinical effectiveness.The LP-PRP group demonstrated no significant improvements in pain scores compared to control injections.The LR-PRP group demonstrated significantly greater reductions in pain compared to the control group at long-term follow-up.There was no difference in the proportion of patients who achieved treatment success in the LP-PRP group compared to the control group. However, patients who... Read More »
Level 1 Meta Analysis
7%
Synopsis: One hundred and seventeen patients with knee osteoarthritis were randomized to receive either a cold rub gel (n=39), heat therapy (n=40), or no intervention (n=38).Outcomes that were assessed in this trial were pain, function in daily living, sport and recreation, and knee-related quality of life using the Knee Injury and Osteoarthritis Outcome Score (KOOS) at 1, 2, 3, and 4 weeks. Both cold rub... Read More »
Level 1 RCT
6%
Synopsis: Eighty-eight patients with first metatarsophalangeal (MTP) joint osteoarthritis were randomized to receive contoured foot orthoses (n=47) or sham insoles (n=41).The primary outcomes of this trial were pain scores in the first MTP during the last week of follow-up using a numerical rating scale (NRS).Secondary outcomes such as pain and function were assessed using the Foot Health Status Questionnaire (FSHQ) and overall average pain using the Numeric Rating Scale (NRS), and quality of life using the Assessment of Quality of Life instrument.Physical activity was also assessed at 12 weeks using the Physical Activity Scale for the Elderly. No significant differences... Read More »
Level 1 RCT
5%
Synopsis: 50 patients with de Quervain disease were randomized to receive a steroid injection into the extensor pollicis brevis subcompartment only (n=25) or into both the abductor pollicis longus and extensor pollicis brevis subcompartments (n=25).The outcomes of interest included pain on a Visual Analog Scale (VAS) and the incidence of injection-related complications.Results revealed no significant differences in VAS pain scores between the two groups up to 12 weeks follow up.The incidence of skin hypopigmentation was significantly lower in the single-compartment injection group vs. the dual-compartment injection... Read More »
Level 1 RCT
5%
Synopsis: Twenty-six patients with sacroiliac joint pain were randomized to either the corticosteroid injection group (n=11) or the intra-articular platelet-rich plasma injection (PRP; n=15) group.The two primary outcomes of this trial were pain on the numeric pain rating scale (NPRS) and functional disability using the Oswestry Low Back Pain Disability Questionnaire (ODI), measured at 1, 3, and 6 months. Significant differences were... Read More »
Level 1 RCT
4%
Synopsis: Sixty-four patients with carpal tunnel syndrome were randomized to receive a single ultrasound-guided corticosteroid hydrodissection (n=32) or a corticosteroid perineural injection (n=32).The primary outcome measure was the symptom severity subscale on the Boston Carpal Tunnel Questionnaire (BCTQ).Secondary outcomes of interest included the functional status subscale of BCTQ, distal motor latency, and sensory nerve conduction velocity of the median nerve.Follow up was performed at 6 and 12 weeks post-injection. No significant differences... Read More »
Level 1 RCT
4%
Synopsis: Eighty-nine female patients were randomized to receive either Biodex balance training (n=29), classical training (n=30), or control (n=30). The primary outcome of this trial was to assess dynamic balance after 10 weeks using the Clinical Test of Sensory Interaction and Balance (mCTSIB).Additional outcomes of interest included pain scores at rest, with movement, and at night measured using the Visual Analogue Scale (VAS), physical function determined by the 30-second chair stand test and 40-meter fast-paced walk test, and quality of life measured by the Knee Injury and Osteoarthritis Outcome Score (KOOS).Significantly better overall stability index scores and sway index scores with eyes open were observed in the Biodex balance group vs.the classical and control groups after 10 weeks. All other outcomes... Read More »
Level 1 RCT
4%
Synopsis: Sixty-two patients with early-stage knee osteoarthritis were randomized to receive either auricular acupressure (n=31) or a sham-acupuncture procedure (n=31).The following outcome measures were assessed: Visual Analogue Scale (VAS) for pain scores, Western Ontario and McMaster Universities Index (WOMAC) for knee symptom scores, and non-steroidal anti-inflammatory drug (NSAID) consumption.Significant differences in VAS and WOMAC scores were apparent at 3 and 7 days post-intervention with better scores in the auricular acupressure group. Significant differences were... Read More »
Level 1 RCT
3%
Synopsis: One hundred and seven patients with medial compartment osteoarthritis were randomized to receive unicompartmental knee arthroplasty (UKA; n=57) or total knee arthroplasty (TKA; n=50).The primary outcomes of this trial were to assess patient-reported outcomes such as Knee Injury and Osteoarthritis Outcome Score, Joint Replacement (KOOS, JR), Knee Society Score (KSS), Forgotten Joint Score (FJS), range of motion (ROM), and VR-12 global health scores at 6 weeks and 6 months follow-up.Radiographic and surgical complications were also recorded.The results of this trial showed no significant differences in KOOS, JR, KSS, and FJS at 6 weeks and 6 months follow-up. Significant differences were... Read More »
Level 1 RCT
3%
Synopsis: Forty patients with chronic knee osteoarthritis were randomized to either the home-exercise smartphone application program (n=20) or the paper-based home exercise program (n=20).The primary outcome of this trial was to determine the adherence rate to the exercise program at 3 and 6 weeks.Secondary outcomes such as pain intensity (Arabic Numeric Pain Rating Scale (ANPRS)), knee function (Arabic version of Western Ontario and McMaster Universities Index (ArWOMAC)), and Five-Times Sit-to-Stand Test (FTSST) were measured. The results of... Read More »
Author verified Level 1 RCT