Loading...
Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
To focus on specific sub specialties check/uncheck boxes on left
22%
19%
19%
11%
9%
6%
5%
4%
3%
2%
Displaying
100%
7%
Synopsis: Six ACE Reports were identified from the OrthoEvidence database which compared intra-articular injection(s) of hyaluronic acid to corticosteroid in the treatment of osteoarthritis of the knee.All of the included studies were randomized controlled trials which reported pain and/or functional outcomes within 6 months of intervention.Pooled analysis of pain on a visual analog scale indicated that pain relief was significantly better with hyaluronic acid injections at both 3 and 6 months follow-up; however, this finding was strongly influenced by two studies of lower methodological quality. No significant differences between hyaluronic acid and corticosteroid injections were observed in any functional outcome measurement.Due to incomplete or lack of reporting adverse events, an assessment of safety could not be performed along with this review. Furthermore, these findings... Read More »
ACE Review
7%
Synopsis: One hundred and forty hips scheduled for a total hip arthroplasty were randomized to receive a metal-on-polyethylene bearing (n=69 hips) or a ceramic-on-ceramic bearing (n=71 hips).Outcomes of interest included aseptic revision rate, rate of component loosening, rate of periarticular osteolysis, the Western Ontario and McMaster University (WOMAC) osteoarthritis scores, the incidence of ceramic fracture, and implant survivorship.The minimum follow-up time was 20 years.Results revealed significantly greater survivorship, lower aseptic revision rate, lower rate of periarticular osteolysis, and greater functional scores in the ceramic-on-ceramic group compared to the metal-on-polyethylene group (p<0.05 for all). No cases of... Read More »
Conference Report
3%
Synopsis: 72 patients were randomized to compare the efficacy of Platelet Rich Plasma (PRP) or hyaluronic acid (HA) for the treatment of chondropathy or early knee osteoarthritis (OA).Results at the 6-month follow-up revealed that both groups displayed a significant improvement in regards to function and quality of life. However, there were... Read More »
Conference Report
3%
Synopsis: Six ACE Reports (5 randomized controlled trials and 1 systematic review/meta-analysis) were identified from the OrthoEvidence database which evaluated the efficacy of platelet-rich plasma in the treatment of knee osteoarthritis.All included studies were randomized controlled trials, and reported clinical and functional assessment at various time points between 1 and 6 months following treatment.Pooled analysis of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Total scores suggested a possible beneficial effect with PRP injection in comparison to saline and a lower effect versus hyaluronic acid.Beneficial effects were also noted for individual subscales of the WOMAC assessment (pain, stiffness, and physical function).However, pooling of OMERACT-OARSI responders and a review of the literature indicated that there was no significant difference between PRP and comparison groups in other functional outcome measures, such as the International Knee Documentation Committee (IKDC) assessment and Knee Injury and Osteoarthritis Outcome Score (KOOS).Furthermore, contrasting results were obtained between two studies reporting function on the Lequesne Index. The discrepancy in... Read More »
ACE Review
3%
Synopsis: 192 patients, older than 18 years, with chronic pain or swelling of knee and degeneration of the joint were randomized to be treated either with platelet rich plasma (PRP) or viscosupplementation (Hyaluronic Acid-HA) injections.To compare both treatment modalities for knee chondropathy or early osteoarthritis (OA), a year of clinical evaluation demonstrated that both groups had significant improvements in function and quality of life. No major adverse... Read More »
Conference Report
3%
Synopsis: 176 patients were randomized to determine the efficacy of three intra-articular injections of plasma rich in growth factors (PRGF) versus hyaluronic acid (HA) injections in the treatment of symptomatic knee osteoarthritis.Clinical outcome using the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) was measured over 6 months. The results indicated... Read More »
Conference Report
3%
Synopsis: This 16 study meta-analysis/systematic review evaluated the ability of platelet-rich plasma (PRP) to improve functional outcomes of patients suffering from knee cartilage degeneration.The aim of the study was to determine the best course of care and treatment for patients with chondral degenerative knee lesions by comparing functional outcomes before and after the use of PRP injections, HA injections, and placebo controls.Results revealed that the injection of PRP improved function and was more effective compared to HA administration. Additionally, patients with... Read More »
Author verified Level 3 Meta Analysis
3%
Synopsis: Twenty-two patients with chronic patellar tendinopathy were randomized to receive either an autologous blood injection (ABI) or saline injection to the patellar tendon.Participants were followed-up for 12 months thereafter using the McGill Pain Questionnaire and Victorian Institute of Sport Assessment (VISA) scale. Both the ABI... Read More »
Conference Report
3%
Synopsis: 200 patients with inflammatory soft tissue tendonitis, Achilles tendonitis, or plantar fasciitis were randomized to evaluate the efficacy of the Orthobiologics Platelet Rich Plasma (PRP) intralesional injection as compared to that of steroid injections.Patients were monitored over 2 years based on the Roles-Maudsley score (RM Score), a visual analog scale, and the American Orthopaedic Foot and Ankle Society (AOFAS) score. While results at... Read More »
Conference Report
3%
Synopsis: Data from 6 randomized controlled trials (RCTs) was systematically reviewed to investigate the efficacy of platelet-rich plasma (PRP) for the management of chronic lateral epicondylar tendinopathy, compared to placebo or other treatments.The search identified six randomized controlled trials of variable methodological quality (PEDro). The evidence presented... Read More »
Author verified Level 2 Meta Analysis