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You are viewing the most viewed ACE Reports by Sports Medicine Specialists over the last 30 days in all specialties.
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100%
7%
①
Synopsis:
One hundred twenty-eight patients with knee osteoarthritis were randomized to receive prolotherapy with 5% dextrose (n=30), 10% dextrose (n=30), 20% dextrose (n=30), or exercise plus hotpack only (n=30).All prolotherapy groups received three injection sessions at weeks 0, 3, and 6, combined with a home exercise program and hotpack therapy.The primary outcome was pain assessed by VAS.Secondary outcomes included WOMAC scores, knee range of motion, timed up and go (TUG) test, and SF-36 quality of life scores.Outcomes were measured at baseline, 6 weeks, and 12 weeks.Overall, results showed that 10% and 20% dextrose groups had significantly greater pain reduction and functional improvements compared with exercise alone, while 20% dextrose also improved knee flexion. The findings suggest...
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Level 1 RCT
5%
①
Synopsis:
Ninety patients with painful trapeziometacarpal osteoarthritis were randomized to receive a single intra-articular injection of platelet-rich plasma (n=45) or saline placebo (n=45).The primary outcome was change in pain on load (NRS 0–100) from baseline to 6 months.Secondary outcomes included change in pain on load at 3 months, pain at rest, Patient-Rated Wrist and Hand Evaluation (PRWHE) score, Disability of the Arm, Shoulder, and Hand (DASH) score, thumb range of motion, and pinch strength at 3 and 6 months.Overall, the results showed no significant difference in pain on load at 6 months between PRP and placebo, and no clinically relevant differences in secondary outcomes. The study concludes...
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Level 1 RCT
4%
②
Synopsis:
144 patients with primary complete Achilles tendon rupture were randomized to be treated with either a surgical repair and accelerated functional rehabilitation or with only the accelerated functional rehabilitation. Over the course of a two year follow up, it was observed that Achilles tendon rupture led to clinically similar results between the two treatment groups.
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Level 2 RCT
4%
Perioperative Blood Flow Restriction Therapy Program After Anterior Cruciate Ligament Reconstruction
①
Synopsis:
Forty-six patients who sustained an anterior cruciate ligament (ACL) tear and were scheduled for reconstruction were randomized into a group receiving either a blood flow restriction (BFR) therapy program (n=22) or a control group without BFR (n=24).The primary outcome of interest was isometric quadriceps strength at 3 months postoperatively, measured as peak and mean torques during seated leg extension exercises and presented as a ratio of the healthy limb.Secondary outcomes included patient-reported outcomes such as pain, knee function, and physical function, knee range of motion, quadriceps circumference and adverse effects.Outcomes were assessed up to 6 months postoperatively. Overall, the study...
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Level 1 RCT
4%
①
Synopsis:
Ninety-three patients with severe knee or hip osteoarthritis were randomized to receive either high-intensity interval training (HIIT; n=30), passive heat therapy (Heat; n=30), or home-based exercise (Home; n=33) as prehabilitation before total hip or knee arthroplasty.The primary outcome of interest was peak oxygen consumption (peak 𝑉𝑂2).Secondary outcomes included the anaerobic threshold, physical function measures, and subjective health assessments.Outcomes were assessed over a 12-week period.Overall, the results revealed that HIIT significantly improved peak 𝑉𝑂2V and the anaerobic threshold compared to the other groups.Heat therapy also increased the anaerobic threshold but not peak 𝑉𝑂2. These findings suggest...
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Level 1 RCT
4%
①
Synopsis:
Sixty patients with rotator cuff tears undergoing open repair were randomized to receive either gabapentin 600 mg daily in two divided doses starting 3 days before surgery and continuing for 1 week postoperatively (n = 30) or placebo (n = 30).The primary outcome was postoperative pain intensity (NRS) over the first postoperative week.Secondary outcomes included opioid (morphine, oxycodone) consumption, sleep quality and duration, side effects, and patient satisfaction.Outcomes were assessed repeatedly during hospitalization and daily until postoperative day 7.Overall, the gabapentin group had significantly lower pain scores from the first 24 hours to day 4, reduced morphine use in the first 6 hours and oxycodone use over 1 week, longer and better-quality sleep until day 5, and higher satisfaction, without increased adverse effects. These findings suggest...
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Level 1 RCT
3%
②
Synopsis:
101 patients with an acute grade 1 or 2 ankle sprain were randomized to be managed with an early therapeutic exercise program or a conventional PRICE (protection, rest, ice, compression and elevation) protocol.It was observed that after early incorporating therapeutic exercises during the first week after an ankle sprain brings about significant improvements in physical activity and improved functional status compared to the standard treatment at weeks 1 and 2. At 16-week follow-up,...
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Author verified Level 2 RCT
3%
Synopsis:
30 blinded randomized controlled trials evaluating the use of hyaluronic acid injections in comparison to a placebo injection in patients with knee osteoarthritis were included in this systematic review and meta-analysis.The objective of this systematic review and meta-analysis was to compare the efficacy and safety of hyaluronic acid injections across different dosing regimens.At 3 months, data were available for 2-4 injection and 5+ injection groups.The 2-4 injection groups demonstrated significantly lower pain scores compared placebo (SMD -0.76 p<0.00001), while the 5+ injection groups did not demonstrate significantly lower pain compared to placebo (SMD -0.20; p=0.09).At 6 months, both the 2-4 injection group (SMD -0.36; p=0.008) and 5+ injection group demonstrated significantly lower pain compared to placebo (SMD -0.18; p=0.04).The single injection groups did not significantly reduce pain compared to placebo at 6 months (SMD -0.04; p=0.67).When looking at the incidence of adverse events, only the 5+ injection group demonstrated a significantly greater incidence compared to placebo (RR 1.67; p=0.02).
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Meta Analysis
2%
②
Synopsis:
109 patients with degenerative knee cartilage were randomized to determine the efficacy of platelet-rich plasma (PRP) compared to viscosupplementation via hyaluronic acid (HA) as a treatment method.Patients were allocated to three injections of either solution, and were followed up for 12 months.Results revealed that there were no differences between groups in clinical outcome for the duration of the study. Interestingly, a sub-group...
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Level 2 RCT
2%
②
Synopsis:
186 patients with a severe lateral ankle sprain (type III) were randomized to treatment to 3 weeks of rigid immobilization with a walking boot followed by 3 weeks of immobilization with a functional brace, or to a functional brace for 6 weeks.The purpose was to compare these two conservative treatment methods for outcomes in pain, function, and ankle stability up to 12 weeks after the injury.AOFAS scores were better for the first 6 weeks in patients receiving the functional brace, and pain and comfort outcomes also benefited within the first few weeks from using a functional brace. By 12 weeks,...
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Author verified Level 2 RCT