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Synopsis: This systematic review and meta-analysis included 21 studies comprising 1,356 patients diagnosed with plantar fasciitis comparing platelet-rich plasma (PRP) therapy versus other conservative treatments.Pooled outcomes of interest were pain (visual analog scale, VAS), plantar fascia thickness (PFT), foot function (Foot Function Index, FFI), and functional scores (American Orthopaedic Foot and Ankle Society, AOFAS).PRP showed significantly greater reductions in pain scores compared to ESWT, CSI, and placebo, and it improved AOFAS scores more than CSI and placebo.However, no consistent superiority was observed in PFT and FFI outcomes. These findings suggest... Read More »
Level 1 Meta Analysis
3%
Synopsis: One hundred patients with ankle osteoarthritis were randomly assigned to receive either intra-articular platelet-rich plasma injections (PRP; n=48) or intra-articular placebo injections (n=52).The primary outcome was the patient-reported American Orthopaedic Foot & Ankle Society (AOFAS) score over 52 weeks.Secondary outcomes included various patient-reported measures assessing pain, function, quality of life, and indirect costs over the same period.The adjusted between-group difference for the patient-reported AOFAS score at 52 weeks favored the placebo group by 2 points (95% CI, 25 to 2; P = .31).With regards to secondary outcomes, there were no statistically significant between-group differences observed as was measured at 52 weeks post procedure. Overall, this indicates... Read More »
Level 1 RCT
3%
Synopsis: Forty-three patients with displaced Lisfranc injuries were randomized to receive open reduction and internal fixation (ORIF, n=22) or primary arthrodesis (PA, n=21).The primary outcome was the Visual Analogue Scale Foot and Ankle (VAS-FA) score at 24 months.Secondary outcomes included subscales of the VAS-FA (pain, function, and complaints) and the American Orthopaedic Foot & Ankle Society (AOFAS) Midfoot Scale, assessed at 6, 12, and 24 months.Overall, the results revealed no significant differences in VAS-FA or AOFAS scores between the two groups across all follow-up points.Both ORIF and PA appear to be viable initial surgical methods for displaced Lisfranc injuries. However, the study... Read More »
Level 1 RCT
3%
Synopsis: Ten randomized clinical trials, including 497 patients with rotator cuff disorders, were included in this systematic review and meta-analysis, which compared telemedicine-based rehabilitation with conventional rehabilitation.Outcomes of interest included the Constant-Murley Score (CMS), Quick Disabilities of the Arm, Shoulder, and Hand (Quick DASH) score, range of motion (ROM), and pain levels assessed by the visual analog scale (VAS).The pooled results demonstrated that telemedicine significantly improved shoulder function and pain relief compared to traditional rehabilitation. This suggests that... Read More »
Level 1 Meta Analysis
3%
Synopsis: One hundred and one patients undergoing primary total hip arthroplasty were randomized to receive either the direct anterior approach (DAA, n=52) or the mini-posterior approach (MPA, n=49).The primary outcome assessed was the Harris Hip Score (HHS).Secondary outcomes included the 12-Item Short Form Health Survey (SF-12) physical and mental scores, Hip Disability and Osteoarthritis Outcome Score (HOOS) subscores, complication rates, reoperations, and revisions.Outcomes were evaluated over a mean follow-up period of 7.5 years.Overall, results demonstrated no clinically meaningful differences in primary or secondary outcomes, including complication rates and revisions, between the two approaches. Read More »
Level 1 RCT
3%
Synopsis: Eight studies including 548 patients with trigger finger were included in this systematic review and meta-analysis comparing percutaneous A1 pulley release versus open A1 pulley release.Pooled outcomes of interest included revision rates, complication rates, postoperative pain, patient satisfaction, and return to normal activity.The meta-analysis found no statistically significant differences between the two techniques in the need for revision (p = 0.27), complication rates (p = 0.84), or postoperative pain (p = 0.54). The main findings... Read More »
Level 1 Meta Analysis
3%
Synopsis: 16 studies including 1402 patients with osteoarthritis were included in this systematic review and meta-analysis comparing the effectiveness of yoga interventions versus pharmacological and non-pharmacological treatments.Pooled outcomes of interest included pain and function.Pooled results demonstrated that yoga interventions significantly reduced pain and improved function.Most effective yoga interventions included supervised sessions supplemented with home-based practices. The study suggests... Read More »
Level 1 Meta Analysis
2%
Synopsis: One hundred and eighteen patients with symptomatic knee osteoarthritis were randomized to receive either intra-articular micro-fragmented adipose tissue injections (MF-AT; n=59) or platelet-rich plasma injections (PRP; n=59).The primary outcome of this trial was the change in International Knee Documentation Committee (IKDC) scores and pain subscale of the Knee Osteoarthritis Outcome Score (KOOS) from baseline to 6 months.Other outcomes such as KOOS subscales for functional improvement, EuroQol visual analog scale (EQ-VAS), EuroQol 5 Dimensions (EQ-5D), and Visual Analog Scale (VAS) for pain at 3, 6, 12, and 24 months.MRI findings using the Whole-Organ Magnetic Resonance Imaging (WORMS) score was also assessed.Statistically significant improvements in all clinical scores were apparent in the MF-AT group, except for EQ-VAS scores. IKDC and KOOS... Read More »
Level 1 RCT
2%
Synopsis: 482 patients with a first-time traumatic anterior shoulder dislocation were randomized to receive either one session of advice + supporting materials + the option to self-refer to physiotherapy (n=240) or the same advice + supporting materials plus an additional program of physiotherapy (n=242).The primary outcome of interest was the Oxford shoulder instability score (OSIS) at 6 months.Secondary outcomes of interest included the Disablities of the Arm, Shoulder, and Hand (QuickDASH) score, EuroQol-5 Dimensions (EQ-5D-5L) score, and the incidence of complications.Outcomes were assessed at 6 weeks, 3, 6, and 12 months.Overall, the results of the study revealed no significant differences in OSIS scores between the two groups at six months.All secondary outcomes were similar between the two groups at all time points. The additional program... Read More »
Author verified Level 1 RCT
2%
Synopsis: One hundred twenty patients with anterior cruciate ligament (ACL) injuries were randomized to receive either postoperative intra-articular PRP injection (n=60) or no injection (control group; n=60) following ACL reconstruction.The primary outcome was the mean Knee Injury and Osteoarthritis Outcome Score (KOOS4) at 12 months postoperatively.Secondary outcomes included patient-reported outcomes, graft maturity (via MRI), and physical examinations conducted at 3, 6, and 12 months.Overall, the results indicated no statistically significant improvement in knee function or symptoms in the PRP group at 12 months. At 6 months,... Read More »
Level 1 RCT