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You are viewing the most viewed ACE Reports by Orthopaedic Surgeons over the last 30 days in all specialties.
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Synopsis:
Fifty-seven patients with displaced type II distal clavicle fractures were randomized to receive either operative treatment (n=27) or non-operative treatment (n=30).The primary outcome of interest was the Disabilities of the Arm, Shoulder, and Hand (DASH) score at two years.Secondary outcomes included union rates, re-operation rates, satisfaction with shoulder appearance, and return to activities.Outcomes were assessed at one and two years.Overall, the results revealed no significant difference in DASH scores between the two groups at two years, indicating excellent function in both groups.However, 48% of the operative group required hardware removal, while 20% of the non-operative group required surgical intervention due to non-union.Union rates were comparable at two years. These findings suggest...
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Conference Report
Synopsis:
Seventy patients with isolated, closed humeral shaft fractures were randomized to receive either open reduction and plate fixation (n=36) or functional bracing (n=34).The primary outcome of interest was the DASH score at three months.Secondary outcomes included health-related quality of life (HRQoL), pain scores, shoulder/elbow range of motion, complications, and return to activity over one year.Overall, the results revealed that surgery led to superior functional outcomes at three months (mean DASH 24.5 vs.39.4; MD 15.0, p=0.006) and improved HRQoL and pain scores over the first six months.Surgery also resulted in better shoulder and elbow mobility and a higher rate of return to sport.However, by one year, there were no significant differences between groups. These findings suggest...
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Conference Report
①
Synopsis:
One hundred twenty-four patients with postoperative stiffness after primary TKA due to osteoarthritis were randomized to receive either MUA with PT alone (n=58) or MUA with PT plus one dose of pre-MUA intravenous dexamethasone (8 mg) and 14 days of oral celecoxib (200 mg) (n=66).The primary outcome of interest was knee ROM at 6 weeks after MUA.Secondary outcomes included knee ROM at 1 year and clinical outcome measures at both time points.Outcomes were assessed immediately after MUA, at 6 weeks, and at 1 year.Overall, the results revealed that while MUA significantly improved ROM immediately by 46°, there was no statistically significant difference between the treatment and control groups at 6 weeks or at 1 year.Clinical outcomes were also similar between groups. These findings suggest...
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Level 1 RCT
①
Synopsis:
This systematic review and meta-analysis included 24 randomized controlled trials with 1711 participants diagnosed with sciatica due to lumbar disc herniation.It compared surgical treatment, primarily discectomy, to non-surgical treatments and epidural steroid injections.The primary outcomes assessed were leg pain and disability, while secondary outcomes included adverse events, back pain, quality of life, and treatment satisfaction.The pooled results indicated that discectomy provided moderate reductions in leg pain in the short term, with diminishing benefits over time.Effects on disability were smaller, showing only minor improvements.The long-term outcomes revealed no significant differences between surgical and non-surgical treatments. These findings suggest...
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Level 1 Meta Analysis
Synopsis:
Ninety-four patients with periprosthetic distal femur fractures (PPDFs) were randomized to receive locked plating (LP; n=53) or retrograde intramedullary nailing (RIMN; n=41).The primary outcome of interest was the Timed Up and Go (TUG) test at 3 months.Secondary outcomes included the Knee Society Score (KSS), rates of nonunion, malunion, reoperation, and mortality.Outcomes were assessed at 2 weeks, 6 weeks, 3 months, 6 months, 12 months, and 24 months.Overall, the results of the study revealed no significant differences between the two fixation strategies in terms of functional outcomes, including TUG and KSS scores, at any time point.However, malunion was significantly more common in the RIMN group (36.1%) compared to the LP group (9.3%) (p=0.003).Although nonunion and reoperation occurred more frequently in the LP group, these differences were not statistically significant. The findings suggest...
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Conference Report
①
Synopsis:
Two hundred ten patients with shoulder impingement syndrome were randomized to receive either arthroscopic subacromial decompression (ASD) (n=59), diagnostic arthroscopy (n=63), or exercise therapy (n=71).The primary outcomes of interest were shoulder pain at rest and on arm activity, measured using a Visual Analogue Scale (VAS).Secondary outcomes included Constant-Murley score, Simple Shoulder Test score, SF-36, and 15D health-related quality of life measures.Outcomes were assessed over five years.Overall, the results of the study revealed no clinically significant differences between ASD and diagnostic arthroscopy, nor between ASD and exercise therapy, in reducing shoulder pain or improving function. The study suggests...
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Level 1 RCT
Synopsis:
Three hundred ninety-four patients with orthopedic trauma were randomized to receive either CEAA supplementation (n=XX) or a standard diet (n=XX).The primary outcome of interest was changes in fat-free mass (FFM).Secondary outcomes included complication rates, surgical site infections, unplanned reoperations, and mortality.Outcomes were assessed at baseline, 2, 6, and 12 weeks postoperatively, with complications monitored up to one year.Overall, the results revealed that patients with open fractures/polytrauma (OF/PT) experienced significant muscle loss at six weeks, while fragility fracture (FFx) patients lost muscle mass at 12 weeks.Patients with isolated fractures (IFx) gained muscle mass at 12 weeks.CEAA supplementation appeared to mitigate muscle loss in the OF/PT and FFx groups and was associated with a reduced risk of non-union, mortality, and total complications. These findings suggest...
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Conference Report
①
Synopsis:
Seventeen thousand eight hundred two patients with no history of cardiovascular disease or diabetes but with elevated hs-CRP were randomized to receive rosuvastatin 20 mg daily (n=8,901) or placebo (n=8,901).The primary outcome of interest was incident fracture.Secondary outcomes included subgroup effects by sex and hs-CRP tertiles, as well as site-specific fracture rates.Outcomes were assessed for a median follow-up of 1.9 years.Overall, the results of the study revealed no significant difference in fracture rates between the rosuvastatin and placebo groups (adjusted HR 1.06, 95% CI 0.88–1.28; p=0.53). The study concludes...
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Level 1 RCT
①
Synopsis:
100 patients with musculoskeletal trauma were randomized to receive either a conservative transfusion strategy (transfusion at hemoglobin <5.5 g/dL; n=50) or a liberal transfusion strategy (transfusion at hemoglobin <7.0 g/dL; n=49).The primary outcome was the rate of infections, while secondary outcomes included deep vein thrombosis, renal insufficiency, and cardiac events.Outcomes were assessed at 30 days.Overall, the results revealed that the conservative group had no infections, while the liberal group had a 14% infection rate, with statistically significant differences noted. The study suggests...
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Level 1 RCT
①
Synopsis:
Five hundred seventy-six patients with rotator cuff tears were randomized to receive arthroscopic rotator cuff repair with bone marrow stimulation (n=284) or without bone marrow stimulation (control, n=292).The primary outcome of interest was the retear rate.Secondary outcomes included the Constant score, the American Shoulder and Elbow Surgeons (ASES) score, and the visual analog scale (VAS) score.Outcomes were assessed up to 24 months.Overall, the results revealed no statistically significant differences between groups in retear rates or in functional scores (e.g., Constant score, ASES score, or VAS). The study concluded...
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Level 1 Meta Analysis