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3%
Synopsis: Three randomized controlled trials were included in this meta-analysis comparing pain and functional improvement between operative and nonoperative treatment for full-thickness rotator cuff tears.Follow-up was 12 months in each study. Results demonstrated that... Read More »
Author verified Level 1 Meta Analysis
3%
Synopsis: 3424 patients scheduled for or who had undergone either total knee or hip arthroplasty with a 5-day course of rivaroxaban 10mg postoperatively were randomized to extended thromboprophylaxis with either aspirin 81mg daily or continued rivaroxaban 10mg daily.Patients were assessed for the incidence of venous thromboembolism and bleeding events over the first 90 days after surgery, Noninferiority analysis for efficacy demonstrated that extended aspirin was noninferior to extended rivaroxaban. Groups also demonstrated... Read More »
Conference Report
3%
Synopsis: 150 patients with an acute displaced midshaft clavicle fracture were randomized to treatment through either open reduction and internal fixation with a plate or nonoperative management with sling immobilization.Patients were followed-up at 6 weeks, 3 months, 6 months, and 12 months for outcome related to the Disabilities of the Arm, Shoulder, and Hand score, the Constant score, and the incidence of nonunion.Outcome on both the DASH score and the Constant score significantly favoured the plate group compared to the sling group at 6-week and 3-month follow-up, but no significant between-group differences were observed in the measures at 6 months or 12 months. The incidence of... Read More »
Level 2 RCT
2%
Synopsis: 9 studies (8 RCTs, 1 controlled clinical trial) were selected for a systematic review of elderly patients with a proximal humerus fracture.The goal of this study was to determine whether surgical or nonoperative treatment is the optimal intervention in patients over the age of 60.Operative treatments identified in the included trials were the tension band technique, locking plates, pinning and hemiarthroplasty.The results of this review indicated that many studies did not find a significant difference in functional outcomes when comparing locking plates or tension bands to nonoperative treatment at 1 year.There was a significantly better health-related quality of life and Euroqol-5D in patients that received a hemiarthroplasty compared to the nonoperative group for patients with 4-part fractures.Complications were common in the operative treatment groups. This study highlights... Read More »
Level 2 Meta Analysis
2%
Synopsis: Five randomized controlled trials were included in this meta-analysis comparing the outcomes of surgical repair and either subacromial decompression or conservative treatment. Meta-analysis of functional outcome scores demonstrated significantly favourable results of repair compared to both subacromial decompression alone or conservative treatment. Read More »
Conference Report
2%
Synopsis: Seven randomized controlled trials were included in this meta-analysis evaluating the efficacy of corticosteroid injections in the treatment of enthesopathy of the extensor carpi radialis brevis origin.Included RCTs featured local anesthetic or placebo saline injections as a control.Results demonstrated significantly lower pain at 1 month with corticosteroid versus control injections, but no significant difference at 3 and 6 months. Functional scores and... Read More »
Author verified Level 1 Meta Analysis
2%
Synopsis: 18 patients with a displaced (>2mm) base of the 5th metatarsal fracture were randomized to be treated with either open reduction and internal fixation (ORIF) or nonoperative management with a short leg cast.The purpose of this study was to compare clinical measures of pain and function, time to union, and restoration of injured metatarsal length between groups.Follow-up was performed for an average of 8.5 weeks.Results demonstrated no significant differences in pain or functional scores, despite a significantly shorter time to union in the operative group. Read More »
Level 2 RCT
2%
Synopsis: 1583 patients with symptomatic knee osteoarthritis were randomized to either glucosamine monotherapy, chondroitin monotherapy, combined glucosamine and chondroitin therapy, celecoxib 200mg daily, or placebo.Patients were assessed over 24 weeks of treatment.In the primary analysis, only the celecoxib group demonstrated a significantly higher rate of patients attaining the primary efficacy endpoint - a reduction of WOMAC pain by a minimum of 20% relative to baseline - compared to placebo. However, when only... Read More »
RCT
2%
Synopsis: 182 patients scheduled for total knee arthroplasty were randomized to either perioperative intravenous dexamethasone administration, including one dose preoperative and subsequent doses at 24 and 48 hours afterward, to a single preoperative intravenous dexamethasone infusion, or to no dexamethasone administration.Patients were assessed for pain scores, analgesic consumption, incidence of postoperative nausea and vomiting, antiemetic use, and the incidence of complications. Results demonstrated that... Read More »
Level 2 RCT
2%
Synopsis: 60 patients with bilateral secondary knee osteoarthritis to corticosteroid-induced osteonecrosis were randomized to have one knee treated with subchondral injection of mesenchymal stem cells, and one knee treated with total knee arthroplasty.Patients were assessed over a minimum of 8 years after treatment.Results demonstrated no significant difference between groups in outcome on the Knee Society Score at final follow-up. Rate of secondary... Read More »
Level 2 RCT