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You are viewing the most viewed ACE Reports by Orthopaedic Surgeons over the last 30 days in all specialties.
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Platelet-Rich Plasma Injections Are Inferior to Corticosteroid Injections for Short-Term Pain Relief
①
Synopsis:
Fifty-two patients with symptomatic KL II–III knee osteoarthritis (OA) were randomized to receive platelet-rich plasma (PRP) (n=26) or corticosteroid (CS) (n=26).The primary outcome was change in VAS pain.Secondary outcomes were NPRS pain, KOOS JR, and WOMAC.Outcomes were assessed at baseline, 6 weeks, and 3 months.Overall, the results of the study revealed that CS produced significantly larger pain reductions than PRP at 6 weeks and met MCIDs for both VAS and NPRS, whereas groups were similar by 3 months and showed comparable functional gains at both time points. These findings suggest...
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Level 1 RCT
7%
①
Synopsis:
Five hundred thirty-five patients undergoing elective primary Total Hip Arthroplasty (THA) were randomized to cutaneous closure with staples (n=268) or sutures (n=267).The primary outcome was SSI (<6 weeks).Secondary outcomes included prosthetic joint infection (PJI, <1 year), other wound complications (prolonged discharge, dehiscence, necrosis; <6 weeks), and length of stay.Outcomes were assessed during admission, at discharge, then at 2 weeks (removal), 6 weeks, 3 months, and 1 year.Overall, the results of the study revealed a higher—nearly significant—SSI rate with staples and a clearly higher rate of early wound complications, driven by prolonged discharge; PJI did not differ. These findings suggest...
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Level 1 RCT
5%
①
Synopsis:
One hundred and twenty-one patients undergoing a hip arthroscopy procedure were randomized to receive 90 days of automated text messages on post-operative instructions and general health guidance (n=57) or no added intervention (n=64).Outcomes of interest included pain and physical function on the Hip Disability Osteoarthritis Outcome Score (HOOS), patient compliance, and patient satisfaction with the intervention.Results revealed no significant differences between the two groups in pain, physical function, or compliance at 90 days. Patients who received...
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Level 1 RCT
5%
①
Synopsis:
Nine hundred fourty one patients with carpal tunnel syndrome (CTS) were randomized to receive initial surgical decompression (n=470) or initial corticosteroid injection (n=471); further interventions were allowed in both arms as needed.The primary outcome was recovery at 18 months (CTS-6 <8).Secondary outcomes included time to recovery, serial CTS-6, upper-limb function (QuickDASH), palmar pain and pain-related limitation, global perception of recovery, satisfaction, additional treatments, and adverse events.Outcomes were assessed through 18 months at prespecified intervals.Overall, the results of the study revealed that 61% in the surgery group versus 45% in the injection group recovered, and median time to recovery was shorter with surgery (9.0 vs 18.0 months).Patients starting with surgery also had better 18-month QuickDASH, global recovery, and satisfaction, while palmar pain was more frequent early after surgery but comparable by later follow-up. These findings suggest...
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Level 1 RCT
4%
①
Synopsis:
Seventy patients with isolated, closed humeral shaft fractures (HSF) were randomized to operative fixation (n=36) or functional bracing (n=34).The primary outcome was the DASH score at 3 months.Secondary outcomes included EQ-5D/EQ-VAS, SF-12 PCS/MCS, pain, shoulder/elbow ROM, complications, radiographic alignment, and return to work/sport.Outcomes were assessed at 2 and 6 weeks and at 3, 6, and 12 months.Overall, the results revealed better DASH scores with surgery at 6 weeks and 3 months (p=.01 for both), but no differences at 6 or 12 months; surgery also improved early HRQoL and SF-12 MCS to 6 months, with higher return-to-sport rates.Brace-related dermatitis was more common with nonoperative care, and nonunion was numerically higher with bracing. These findings suggest...
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Level 1 RCT
3%
①
Synopsis:
Sixty patients with primary varus gonarthrosis were randomized to receive partial Preservation of the infrapatellar fat pad (IPFP) excision (n=30) or complete IPFP preservation (n=30) during unilateral computer-assisted cruciate-retaining TKA, with identical implants, patellar resurfacing, perioperative care, and blinded outcome assessment.The primary outcome was Anterior Knee Pain (AKP) incidence and severity (VAS≥3).Secondary outcomes were modified WOMAC, ROM, mechanical alignment, and Insall–Salvati ratio.Outcomes were assessed at 1, 3, 6, and 12 months.Overall, the results revealed lower AKP incidence and lower VAS pain at 1 month with preservation, with no between-group differences at later time points.WOMAC was transiently better at 6 months in the preservation group but below MCID; ROM and radiographs were comparable. These findings suggest...
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Level 1 RCT
3%
①
Synopsis:
Sixty patients with primary knee osteoarthritis were randomized to receive intra-articular ozone therapy at 40 µg/mL (n=20), 20 µg/mL (n=20), or oxygen as control (n=20).The primary outcome was pain reduction, measured by the Visual Analog Scale (VAS) and WOMAC pain subscale.Secondary outcomes included functional mobility (WOMAC function, FROM, TUG, and 6MWT).Outcomes were evaluated at baseline, two weeks, one month, and two months post-intervention.Overall, both ozone groups showed significantly greater reductions in pain and improvements in function compared to the control, with no significant differences between the two ozone concentrations. The findings suggest...
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Level 1 RCT
3%
①
Synopsis:
Seventy-five patients with isolated ACL rupture were randomized to bone–patellar tendon–bone (BPTB), single-bundle quadrupled hamstring tendon (HT), or over-the-top HT plus lateral extra-articular tenodesis (HT+LET) (n=25 per arm initially).At final assessment (mean 23.0±1.1 years), 61 completed PROMs, 37 underwent clinical testing, and 35 had radiographs.The primary outcomes were clinical failure/revision and long-term knee function; secondary outcomes included instrumented laxity (KT-1000; pivot-shift), and tibiofemoral/patellofemoral Osteoarthritis (OA) on standardized radiographs.Overall, the results of the study revealed no between-group differences for most PROMs; Tegner activity was slightly higher with HT+LET vs BPTB, AP laxity was lower with BPTB vs HT, and patellofemoral OA was more frequent after BPTB vs HT+LET.There were no differences in tibiofemoral OA or objective IKDC grades. In sum, all...
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Level 1 RCT
2%
①
Synopsis:
Fifty-six patients with lateral malleolar (rotational ankle) fractures were randomized to receive 2-octyl cyanoacrylate (n=27) or n-butyl (90% n-butyl/10% 2-octyl) cyanoacrylate (n=28) for skin closure after standardized plate fixation; fifty-five completed follow-up.The primary outcome was cosmetic appearance by HWES at three and six months.Secondary outcomes included patient satisfaction with cosmesis by VAS (0–100) and 5-point Likert scales at three and six months, and ankle function by OMAS at six months.Overall, the results of the study revealed no statistically significant differences between groups for HWES, VAS, Likert satisfaction, or OMAS at six months. In short, 2-octyl...
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Level 1 RCT
2%
①
Synopsis:
Thirty two patients with full-thickness posterosuperior rotator cuff tears were randomized to immobilization with an abduction neutral-rotation brace (n=16 analyzed) or a conventional arm sling (n=16).The primary outcomes were passive shoulder ROM (forward flexion, external rotation, internal rotation) measured serially; secondary outcomes were pain (VAS) and Constant–Murley Score (CMS).Outcomes were assessed preoperatively and at 6 weeks, 3, 6, and 12 months.Overall, the results revealed better early ROM (e.g., forward flexion and external rotation at 3 months) and lower pain at 6 weeks with the brace, while 12-month ROM converged and CMS was only modestly higher in the brace group at 12 months. These findings suggest...
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Level 1 RCT