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Synopsis: 58 adult patients with isolated Weber Type B ankle fractures were randomized to receive either open reduction and internal fixation (ORIF; n=29) or casting (n=29).Outcomes of interest included the American Orthopaedic Foot and Ankle Society (AOFAS) score and radiographic assessment for fracture union.No significant differences were reported in AOFAS scores between the two groups. Fracture union was... Read More »
Conference Report
6%
Synopsis: Thirteen randomized controlled trials comparing the efficacy of platelet-rich plasma (PRP) against a control group in patients with Achilles tendinopathy (AT) or Achilles tendon rupture (ATR) were included in this meta-analysis.Outcomes of interest included the Victorian Institute of Sport Assessment (VISA-A) score, Achilles tendon thickness, pain on a Visual Analog Scale (VAS), and patient satisfaction.Subgroup analyses were also performed to assess heel raise height, calf circumference, range of motion, return to sport, and incidence of adverse events in patients with ATR. All outcomes at... Read More »
Level 1 Meta Analysis
3%
Synopsis: 29 studies were included in this meta-analysis comparing operative and non-operative treatment for acute Achilles tendon ruptures.The primary outcome of interest was the rate of re-rupture.Secondary outcomes included the rate of complications, functional outcomes, time to return to sports and time to return to work.The results revealed a significantly lower rate of re-rupture, but a higher rate of complications, in the operative group compared to the non-operative group.Similar findings to the primary analyses were observed in the sensitivity analyses based on early and late weight bearing status, high quality studies and studies conducted after the year 2000.There were no significant differences in re-rupture rate in studies utilizing accelerated functional rehabilitation. There was no... Read More »
Level 1 Meta Analysis
3%
Synopsis: One hundred and forty-six patients 35–65 years of age with knee symptoms consistent with a degenerative medial meniscus tear were randomized into receiving arthroscopic partial meniscectomy (APM) or a sham surgery (diagnostic knee arthroscopy).Primary outcomes of interest included radiographic knee osteoarthritis through using the Kellgren and Lawrence knee osteoarthritis grading and the Osteoarthritis Research Society International (OARSI) instrument, as well as patient-related outcomes via the Western Ontario Meniscal Evaluation Tool (WOMET), the Lysholm knee score, and knee pain after exercise.Outcomes of interest were assessed 5 years post-operation.No significant differences between the APM and placebo groups were observed in all three patient-relevant outcomes, 5 years post-operation.A slight increase in the risk of radiographic knee osteoarthritis progression was observed in the APM group, however this was not significantly different.A significantly higher risk of mechanical symptoms was observed in the APM group. Otherwise, outcome comparisons... Read More »
Author verified Level 1 RCT
3%
Synopsis: Four hundred and thirty-nine patients with bicortical scaphoid waist fracture were randomized to receive an open or percutaneous surgical fixation, or cast immobilization for 6-10 weeks.The primary outcome of interest was the Patient Rated Wrist Evaluation (PRWE) total score at 52 weeks post-treatment.Secondary outcomes of interest included PRWE pain and function sub-scale scores, Short Form 12 (SF-12) mental and physical component scores, degree of bone union, range of motion, grip strength, and the incidence of adverse events.Whilst significantly favourable PRWE total scores at 12 weeks, PRWE function scores at 6 and 12 weeks, and grip strength at 6 weeks were significantly in favour of the surgery group (during the period when the cast was still being worn), no significant differences were observed between the groups in all outcomes at 52 weeks. The exception included... Read More »
Level 1 RCT
3%
Synopsis: A meta-analysis of seven studies, including 5 randomized controlled trials, evaluated the impact of using peroxide containing antiseptic solutions compared to control solutions on the burden of Cutibacterium acnes around the shoulder.When evaluating studies using peroxide products in addition to standard preparation, the addition of peroxide significantly diminished the rate of C acnes culture positivity.Subgroup analysis demonstrated that when applied at the time of surgery, peroxide solutions reduced C acnes burden compared to standard preparations. When given in... Read More »
Level 2 Meta Analysis
3%
Synopsis: 5 randomized controlled trials (n=226) were included in this systematic review and meta-analysis comparing the use of adhesive drapes to control in orthopaedic surgery.The main objectives of this meta-analysis was to determine whether the use of adhesive drapes will decrease the risk of wound contamination; whether intraoperative drape peeling increases the risk of wound contamination; and if the use of an adhesive drape will decrease the risk of infection at the surgical site.Five eligible RCTs (n=2266) were identified for analysis.The results of this meta-analysis found that adhesive drapes are effective in decreasing the risk of contamination. The available evidence... Read More »
Conference Report
3%
Synopsis: Eight randomized trials containing a total of 2096 patients with osteoarthritis were included in this systematic review and meta-analysis comparing topical and oral non-steroidal anti-inflammatory drugs (NSAIDs).Pooled outcomes of interest included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and stiffness sub-scores, pain on a Visual Analog Scale (VAS), and the odds of skin adverse reactions, gastrointestinal adverse reactions, and any adverse event.The results of the meta-analysis found no differences in pooled WOMAC pain, WOMAC stiffness, VAS pain scores, and odds of any adverse event between the two formulations. The pooled odds... Read More »
Level 1 Meta Analysis
3%
Synopsis: 182/230 patients from the PATH-2 trial responded to this 2-year follow-up study of the PATH-2 trial comparing platelet-rich plasma (PRP; n=88/114) and placebo (92/116).The outcomes of interest included the Achilles Tendon Rupture Score (ATRS), the Patient-Specific Functional Scale (PSFS), and the Short-Form 12 (SF-12) mental and physical component quality of life scores. The results of... Read More »
Level 1 RCT
3%
Synopsis: Thirty-four males with Achilles tendon ruptures were randomized to receive photobiomodulation during the 8-week cast immobilization (n=17) or sham photobiomodulation (n=17).The primary outcome of interest was the Achilles tendon rupture score (ATRS).Secondary outcomes of interest included pain at rest and during effort on a Numeric Pain Rating Scale (NPRS), ankle range of motion, and plantar flexor muscle strength.Outcomes were assessed at 8, 12 and 16 weeks post-rupture.The results found no difference in function (ATRS scores) with photobiomodulation vs.control.Moreover, no differences in range of motion, pain at rest, or plantar flexor muscle strength were observed between the two groups. Pain during walking... Read More »
Level 1 RCT