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Synopsis: This meta-analysis aimed to determine the efficacy of using in-office nerve conduction studies (NCS) for identifying median neuropathy (MN), specifically carpal tunnel syndrome.Traditional electrodiagnostic tests were used as the reference standard.MEDLINE was searched for studies that evaluated the aforementioned relationship.Five studies, with a total of 448 symptomatic hands, were included in the meta-analysis. Results illustrated that... Read More »
Level 1 Meta Analysis
14%
Synopsis: 26 patients with chronic lateral epicondylitis were randomized to either surgical intervention with the Nirschl technique, or to a sham procedure involving only incision and exposure of the extensor carpi radialis brevis.Patients were followed up postoperatively for 1 year.Results demonstrated no significant differences between groups in outcome measures of pain frequency or severity, function, range of motion, and grip strength. A major limitation... Read More »
Conference Report
9%
Synopsis: 60 patients with a rotator cuff tear confirmed on MRI were randomized to analgesia through either a suprascapular nerve block (SSNB) or subacromial injection (SA injection) prior to nonoperative management using a standardized physiotherapy protocol.Patients were assessed for shoulder function using the Constant Murley score over a 12-week follow-up. By 12-week follow-up,... Read More »
Conference Report
4%
Synopsis: 121 patients (125 hands; 166 rays) with Dupuytren's disease were randomised to undergo either percutaneous needle fasciotomy (PNF) or limited fasciotomy (LF) treatment.The primary outcome was total passive extension deficit (TPED).Results at the 6-week follow-up indicated that the PNF procedure was less effective as a treatment overall, producing a smaller reduction in TPED when compared to LF. However, PNF provided... Read More »
Level 2 RCT
4%
Synopsis: 230 patients presented with chronic tennis elbow were enrolled and randomized into either a leukocyte enriched platelet-rich plasma treatment group (L-PRP) or an active control group.This study was followed-up at 12 and 24 weeks to evaluate clinical efficacy based on pain and local elbow tenderness.At the 12-week follow-up, no significant differences were observed between the two groups.However, at the 24-week follow-up, clinically significant differences were found, favouring L-PRP-treated patients for outcome measures in pain and local tenderness. Rate of adverse... Read More »
Author verified Level 1 RCT
4%
Synopsis: 67 patients with de Quervain tenosynovitis were randomized to receive treatment with a corticosteroid injection (CSI) alone or in combination with thumb spica casting (TSC).The effectiveness of each treatment was examined and compared in terms of success rate, pain intensity, and functional outcomes.Within 3 weeks, both groups experienced significant improvements in success rates compared to their respective baseline outcomes, but with CSI + TSC achieving significantly better results when compared to CSI alone over the 6 month follow-up. The same trend... Read More »
Level 2 RCT
4%
Synopsis: 126 patients with patellofemoral joint (PFJ) osteoarthritis (OA) were randomized to either a knee support brace, or a control group without brace support for 6 weeks.The purpose of this study was to determine the effects of a flexible knee brace on quadriceps maximum voluntary contraction (MVC) and athrogenous muscle inhibition (AMI) in PFJ OA patients.Patients in the control group were subjected to knee brace wearing after the initial 6 weeks.Knee brace wearing in all participants of the trial lasted for a duration of 12 weeks in the open-label phase of this trial.Findings indicated a significant decrease in AMI after 6 weeks in the brace wearing group compared to the control group, but no significant differences in MVC. All patients demonstrated... Read More »
Level 2 RCT
4%
Synopsis: 10 randomized or quasi-randomized controlled trials were included in this direct meta-analysis and indirect network meta-analysis comparing the results of corticosteroid injection, autologous whole blood injection (AB), and platelet-rich plasma injection (PRP) in the treatment of patients with lateral epicondylitis.The results fo this study indicated that by final follow-up, which ranged from 2-12 months post-injection, both direct and indirect analyses favoured pain and disability results with platelet-rich plasma versus corticosteroid, while only indirect analyses favoured autologous whole blood over corticosteroid. No significant differences... Read More »
Level 2 Meta Analysis
4%
Synopsis: 643 postmenopausal women with osteoporosis who had used oral bisphosphonate for a minimum of 2 years were randomized to either subcutaneous injections of denosumab 60mg - one at baseline and another at 6 months - or intravenous injection of zoledronic acid 5mg.The purpose of this study was to evaluate if denosumab offered noninferior or superior efficacy and safety to zoledronic acid for increasing bone mineral density in this patient population.The increase in the lumbar spine, total hip, femoral neck, and distal one-third radius bone mineral density were superior in the denosumab group compared to the zoledronic acid group. The incidence of... Read More »
Author verified Level 1 RCT
4%
Synopsis: 27 randomized controlled trials (RCT) were included in this bayesian network meta-analysis to provide a comprehensive comparison of injection therapies for lateral epicondylitis.A total of 13 therapies were identified from the literature.The results from this study indicated that for pain reduction, hyaluronic acid and prolotherapy injections were ranked one and two, respectively.However, the fact hyaluronic acid and prolotherapy were each only evaluated in one study highlights the need for additional research.While corticosteroid injections are the most frequently used injection therapy, this analysis indicates it provides suboptimal results, ranking 11th out of 13 treatments.The collection of data at 26 weeks may have led to corticosteroid injections to rank lower due to the transient benefit typically observed for this treatment. Read More »
Level 1 Meta Analysis