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27%
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17%
Synopsis: One hundred and forty hips scheduled for a total hip arthroplasty were randomized to receive a metal-on-polyethylene bearing (n=69 hips) or a ceramic-on-ceramic bearing (n=71 hips).Outcomes of interest included aseptic revision rate, rate of component loosening, rate of periarticular osteolysis, the Western Ontario and McMaster University (WOMAC) osteoarthritis scores, the incidence of ceramic fracture, and implant survivorship.The minimum follow-up time was 20 years.Results revealed significantly greater survivorship, lower aseptic revision rate, lower rate of periarticular osteolysis, and greater functional scores in the ceramic-on-ceramic group compared to the metal-on-polyethylene group (p<0.05 for all). No cases of... Read More »
Conference Report
4%
Synopsis: 107 patients (age range 50 to 90 years), scheduled to undergo primary total knee arthroplasty, were randomized to have a cemented or uncemented femoral component. At the 5th post-operative day, the peri-operative blood losses were found to be similar with the use of a cemented or uncemented femoral component in the total knee arthroplasty procedure. Read More »
Level 2 RCT
4%
Synopsis: 42 patients with osteoarthritis undergoing total hip arthroplasty (THA) involving a cementless system (CLS) stem were randomized postoperatively to one of two groups.The first group participated in early unrestricted weight bearing (UWB) in addition to intensive physiotherapy, while the second group underwent partial weight-bearing (PWB) in addition to self-training.The primary outcome was migration of the uncemented CLS stem. Results indicated that... Read More »
Level 2 RCT
4%
Synopsis: 100 female osteoarthritis patients (200 knees) undergoing total knee arthroplasty (TKA) were randomized to receive a gender specific prosthesis or a standard prosthesis.Over 24 months, the gender specific group demonstrated a significantly greater improvement in range of motion than the standard group. There was no... Read More »
Author verified Level 2 RCT
4%
Synopsis: Patients were randomized to investigate the most suitable treatment for lateral epicondylitis; patients received physiotherapy, Extracorpeal Shockwave Therapy (ESWT), prolotherapy, or Platelet-Rich-Plasma (PRP) treatment. The results of the treatments at the mean 22 month follow-up indicated that prolotherapy and PRP produced better clinical outcomes than the other two groups, where PRP displayed significantly better DASH scores than the prolotherapy treatment. Read More »
Conference Report
4%
Synopsis: 17 randomized controlled trials (RCTs) consisting of 1381 patients with tennis elbow were evaluated to compare 8 types of injection therapies with the goal of determining the efficacy and safety of each.Results indicated that patients treated with autologous blood, platelet-rich plasma, prolotherapy, hyaluronic acid, and botulinum toxin injections experienced significant improvements in pain intensity compared to placebo.There were no significant differences between any of the glucocorticoid, polidocanol, or glycosaminoglycan polysulfate injection therapy groups against a respective placebo, where changes in pain intensity were concerned.Additionally, no serious adverse events were reported in any of the patients, but the most common minor adverse event observed was temporary pain following administration of injections. This meta-analysis strongly... Read More »
Author verified Level 1 Meta Analysis
4%
Synopsis: Fifteen studies (7 randomized controlled trials, 8 observational studies) were included in this systematic review to determine the efficacy and safety of raloxifene in treatment of postmenopausal Japanese women suffering from osteoporosis or osteopenia.Qualitatively, majority of studies reporting on pertinent outcomes of interest demonstrated significant increase lumbar spine bone mineral density from baseline, low overall vertebral and non-vertebral fracture incidence, and significant changes from baseline in bone-specific alkaline phosphatase and type 1 collagen N-telopeptide levels during treatment with raloxifene. The quality of... Read More »
Level 3 Meta Analysis
4%
Synopsis: 73 patients with rotator cuff tendinopathy were randomized to one of three study treatment groups: (1) hypertonic dextrose prolotherapy injection directly to affected entheses, (2) saline injection directly to affected entheses, or (3) saline injection superficial to affected entheses.The purpose of this study was to investigate the clinical benefits of dextrose prolotherapy when compared to control groups by observing improved patient-reported pain scores, patient satisfaction scores, and ultrasound grading of regenerative effect. Results demonstrated that... Read More »
Author verified Level 2 RCT
4%
Synopsis: 27 randomized controlled trials (RCT) were included in this bayesian network meta-analysis to provide a comprehensive comparison of injection therapies for lateral epicondylitis.A total of 13 therapies were identified from the literature.The results from this study indicated that for pain reduction, hyaluronic acid and prolotherapy injections were ranked one and two, respectively.However, the fact hyaluronic acid and prolotherapy were each only evaluated in one study highlights the need for additional research.While corticosteroid injections are the most frequently used injection therapy, this analysis indicates it provides suboptimal results, ranking 11th out of 13 treatments.The collection of data at 26 weeks may have led to corticosteroid injections to rank lower due to the transient benefit typically observed for this treatment. Read More »
Level 1 Meta Analysis
4%
Synopsis: 32 patients who suffered an anterior cruciate ligament tear were included in this trial and randomized to arthroscopic reconstruction or non-operative care.The objective of this study was to compare functional outcome and the effect of these treatment methods on the incidence and progression of knee osteoarthritis over a 10-year follow-up.The results of this trial indicated that functional outcome and knee laxity measures were significantly better in patients who underwent arthroscopic reconstruction compared to non-operative management. There was no... Read More »
Level 2 RCT