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22%
19%
14%
11%
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8%
8%
6%
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100%
13%
Synopsis: One hundred patients with chronic midportion Achilles tendinopathy were randomized to receive either exercise therapy combined with ultrasonography-guided corticosteroid injection (n=48) or exercise therapy with placebo injection (n=52).The primary outcome was improvement in the Victorian Institute of Sport Assessment–Achilles (VISA-A) score at 6 months.Secondary outcomes included tendon thickness, pain during activity and in the morning (measured by VAS), and global assessment of treatment response.Outcomes were assessed at baseline and 1, 2, 3, 6, 12, and 24 months.Overall, the results revealed that the corticosteroid group showed a significantly greater improvement in VISA-A scores at 6 months, accompanied by improved tendon morphology and early symptom relief, with no increase in adverse events. These findings suggest... Read More »
Level 1 RCT
8%
Synopsis: 76 patients with Dupuytren's contracture and a palpable nodule were randomized to one of four groups; 0.25mg collagenase clostridium histolyticum (CCH) injection, 0.40mg CCH injection, 0.60mg CCH injection, or placebo injection.Patients were assessed over 8-week follow-up nodule size and hardness, pain, patient satisfaction, and investigator-rated improvement.After 8 weeks, reduction in nodule size was significantly greater in the 0.40mg and 0.60mg CCH groups compared to placebo, and reduction in nodule hardness was significantly greater in the 0.25mg, 0.40mg, and 0.60mg CCH groups compared to placebo. Composite responder rate... Read More »
Level 2 RCT
8%
Synopsis: 12,211 patients from 21 trauma centers in the United States and Canada were included in this non-inferiority randomized trial comparing aspirin (n=6,101) and low molecular-weight heparin (n=6110).The primary outcome of interest was death by any cause at 90 days.Secondary outcomes of interest included the risk of thromboembolic events (pulmonary embolism; deep-vein thrombosis), cause-specific death, bleeding & wound complications, and the rate of infection.Aspirin was found to be non-inferior to low molecular-weight heparin with respect to the primary outcome of death by any cause. No differences in... Read More »
Level 1 RCT
5%
Synopsis: Three hundred twenty-one patients with degenerative meniscal tears were randomized to receive arthroscopic partial meniscectomy (n=159) or exercise-based physical therapy (n=162).The primary outcome of interest was patient-reported knee function assessed by the International Knee Documentation Committee (IKDC) questionnaire.Secondary outcomes included radiographic progression of knee osteoarthritis, symptomatic OA, pain during activities, physical functioning (KOOS-PS), and quality of life.Outcomes were assessed at multiple time points up to 5 years.Overall, the results of the study revealed that physical therapy was noninferior to surgery for knee function, with no clinically meaningful differences in OA progression or other secondary outcomes. These findings suggest... Read More »
Level 1 RCT
2%
Synopsis: 63 patients, over the age of 50, suffering from both rotator cuff injuries and type II SLAP lesions were randomized to undergo repair of both injuries or only the rotator cuff repair. Results, following a minimum follow-up of 2.9 years, indicated that patients who underwent repair of only the rotator cuff had significantly better UCLA scores and ROM. Read More »
Author verified Level 2 RCT
2%
Synopsis: This systematic review identified 5 studies (four RCTs and one cohort study: total of 365 patients for all studies) that assessed which treatment modality - surgical or conservative - was the optimal treatment for acute, displaced midshaft clavicle fractures.Results indicated that the surgical treatment led to a better functional outcome (measured with the Constant score) and lower mal- and non-union rates compared to conservative treatment. However, clinical relevance... Read More »
Author verified Meta Analysis
2%
Synopsis: 30 patients with carpal tunnel syndrome were randomized to undergo single- or two-incision carpal tunnel release to compare clinical and functional outcomes between surgical techniques.Upon analysis, results revealed no significant difference between groups with respect to the Disabilities of the Arm, Shoulder, and Hand (DASH) Questionnaire, Brigham and Womens Carpal Tunnel Questionnaire (BWCTQ) for symptom severity and functional status, grip strength, pinch strength, scar tenderness, or radial and ulnar pillar pain. The single-incision group... Read More »
Author verified Level 2 RCT
2%
Synopsis: 59 patients (>18 years of age) who were diagnosed with mallet finger (with or without fracture) and who had undergone continuous splint/cast immobilization and hyper-extension intervention (6-8 weeks), were randomly assigned into 1 of 2 treatment groups to determine the effect of an additional one month of night splinting on extensor lag.Participants either received an additional one month intervention with a night splint following their continuous splinting period or received no additional intervention (control). Results from the... Read More »
Author verified Level 2 RCT
2%
Synopsis: 79 women aged 40 years and older diagnosed with severe stage IV osteoarthritis (OA) were randomly assigned to undergo ligament reconstruction and tendon interposition (LRTI) of the basal thumb joint using either the Burton-Pellegrini (BP) or the Weilby technique.The BP technique uses a bone tunnel at the base of the thumb, while the Weilby technique does not.The purpose of this study was to compare the short- and long-term pain and physical function outcomes of both techniques.Findings suggested the BP technique prompted faster recovery than the Weilby technique, with better clinical outcome at 3 months. Outcome at 12... Read More »
Author verified Level 2 RCT
2%
Synopsis: 27 randomized and quasi-randomized trials that investigated safety outcomes in patients undergoing either endoscopic or open carpal tunnel release for carpal tunnel syndrome were included in this meta-analysis.The study was conducted to determine whether earlier concerns regarding the safety of endoscopic release in comparison to an open approach were still applicable presently.The study found that previous drawbacks of an endoscopic release such as high reoccurrence and reoperation rates have been gradually lessened to where they are now comparable with rates in an open approach.Total and major complications are also comparable between groups, whereas minor occurrences were significantly less frequent following endoscopic release. Return to activity... Read More »
Author verified Level 1 Meta Analysis