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Synopsis: Thirty-three randomized controlled trials including 1154 patients with chronic ankle instability were included in this systematic review and meta-analysis comparing strength training, balance training, and a combination of both.Pooled outcomes of interest included self-reported function scores and dynamic balance measures.The combination of strength and balance training showed greater improvements in patient-reported outcomes compared to either intervention alone, with significant improvements in dynamic balance observed only in the balance training group. The findings suggest... Read More »
Level 1 Meta Analysis
10%
Synopsis: Thirty patients who underwent anterior cruciate ligament reconstruction were randomized to receive either an 8-week contralateral neuromuscular knee exercise program (n=15) or routine physiotherapy (n=15).The primary outcomes of interest included the Star Excursion Balance Test (SEBT), Balance Error Scoring System (BESS), Stork Balance Stand Test, and the Lysholm questionnaire.The secondary outcome was pain on a Visual Analog Scale (VAS). The neuromuscular knee... Read More »
Author verified Level 1 RCT
10%
Synopsis: A total of 40 patients with Colles fracture were enrolled in a randomized controlled trial to compare the clinical efficacy of instant 3D printed casts versus polymer orthosis.The participants were randomly assigned to an observation group (treated with instant 3D printed cast; n=20) and a control group (treated with polymer orthosis; n=20).Both groups underwent manual reduction and external fixation.Outcome measures, including visual analogue scale (VAS), immobilization effectiveness and satisfaction scores, Disability of the Arm, Shoulder, and Hand (DASH) scores, complications, and imaging data, were assessed at various time points (before immobilization, 2, 6, and 12 weeks after the fracture).The results revealed that the VAS at 2 weeks, immobilization effectiveness and satisfaction scores at 6 weeks, and DASH scores at 2 and 6 weeks were significantly favorable in the observation group compared to the control group. The study concludes... Read More »
Level 1 RCT
10%
Synopsis: Twenty-one randomized controlled trials including 2004 patients with intertrochanteric femoral fractures were included in this systematic review and meta-analysis comparing rapid rehabilitation care vs.routine care.Pooled outcomes of interest included postoperative complications, wound infections, wound pain, and length of hospital stay.Pooled results indicated that rapid rehabilitation care significantly reduced postoperative complications, wound infections, and wound pain, and shortened the length of hospital stay compared to routine care. The findings suggest... Read More »
Level 1 Meta Analysis
10%
Synopsis: Five randomized controlled trials including 275 patients with 283 trigger digits were included in this systematic review and meta-analysis comparing ultrasound-guided tendon release vs.open surgical release.Pooled outcomes of interest included Quick Disability of Arm, Shoulder, and Hand (QDASH) scores, grip strength, Visual Analogue Scale (VAS) scores, days to return to normal activities, and days to stopping analgesia.The pooled results showed that ultrasound-guided release significantly improved QDASH scores within the first month and reduced the days required to return to normal activities.There were no significant differences in grip strength, VAS scores, full-digit flexion, and extension between the two groups. The findings suggest... Read More »
Level 1 Meta Analysis
3%
Synopsis: Two hundred and twenty-eight patients with primary total hip arthroplasty were randomized to receive either oral tranexamic acid (oral TXA; n=114) or 1 g of intravenous TXA (IV TXA; n=114).The primary outcome of interest was total blood loss (TBL) intra-operatively and up to 48 hours postoperatively.Secondary outcomes included a hemoglobin concentration decrease, D-Dimer levels on days 1 and 3, and transfusion rates.Outcomes were assessed up to 48 hours post-surgery.Overall, the study revealed that oral TXA is non-inferior to intravenous TXA regarding TBL, with the median difference between groups being within the noninferiority margin. The findings suggest... Read More »
Level 1 RCT
3%
Synopsis: One hundred (100) amateur male athletes with anterior cruciate ligament reconstruction (ACLR) were randomized to receive either an accelerated rehabilitation protocol (n=50) or a conventional rehabilitation protocol (n=50).The primary outcome of interest was knee pain, measured using a visual analog scale (VAS).Secondary outcomes included hop test performance, Knee Injury and Osteoarthritis Outcome Score (KOOS), and knee effusion.Outcomes were assessed at baseline and after 22 weeks.Overall, the results of the study revealed that the accelerated rehabilitation protocol significantly improved functional outcomes compared to the conventional protocol, with better scores in hop tests and KOOS subscales, although both protocols were equally effective in reducing knee pain. These findings suggest... Read More »
Level 1 RCT
2%
Synopsis: Thirteen randomized controlled trials including 540 patients with knee osteoarthritis were included in this systematic review and meta-analysis comparing transcranial direct current stimulation (tDCS) vs.sham tDCS.Pooled outcomes of interest included pain, physical function, stiffness, mobility performance, quality of life, pressure pain tolerance, and plasma levels of brain-derived neurotrophic factor (BDNF).Pooled results indicated a significant decrease in pain with tDCS, but no significant improvements in physical function, stiffness, mobility performance, quality of life, or pressure pain tolerance.There was a significant reduction in plasma levels of BDNF. The main findings... Read More »
Level 1 Meta Analysis
2%
Synopsis: Twenty-five randomized controlled trials including 2,170 patients with anterior cruciate ligament (ACL) injuries were included in this systematic review and meta-analysis comparing bone-patellar tendon-bone (BPTB) autograft versus hamstring tendon (HT) autograft, single-bundle versus double-bundle HT autograft, and metal screws versus bioabsorbable screws.Pooled outcomes of interest included revision rates, graft failure, infection, Lysholm scores, and IKDC scores.The results indicated no significant differences between BPTB and HT autografts overall.However, double-bundle HT autograft showed superior outcomes compared to single-bundle in several parameters, and bioabsorbable screws performed better than metal screws in functionality and failure rates. These findings suggest... Read More »
Level 1 Meta Analysis
2%
Synopsis: Five randomized controlled trials including 555 patients with degenerative lumbar spinal stenosis were included in this systematic review and meta-analysis comparing interspinous process device (IPD) vs.decompression surgery.Pooled outcomes of interest included Visual Analogue Scale (VAS) leg and back pain, Oswestry Disability Index (ODI), Zurich Claudication Questionnaire (ZCQ) physical function and symptom severity, complication rate, and reoperation rate.The pooled results showed no significant differences in VAS leg pain, VAS back pain, ODI scores, and ZCQ physical function between IPD and decompression surgery groups.However, decompression surgery was superior in ZCQ symptom severity, and the IPD group had a significantly higher reoperation rate. This study suggests... Read More »
Level 1 Meta Analysis