Leukocyte-Poor Platelet-Rich Plasma For Arthroscopic Rotator Cuff Repair .
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Leukocyte-Poor Platelet-Rich Plasma as an Adjuvant to Arthroscopic Rotator Cuff Repair Reduces the Retear Rate But Does Not Improve Functional Outcomes: A Double-Blind Randomized Controlled Trial.
Am J Sports Med . 2024 May;52(6):1403-1410.Ninety-six patients with rotator cuff tears smaller than 3 cm were randomized to receive either arthroscopic rotator cuff repair (ARCR) with leukocyte-poor platelet-rich plasma (LP-PRP) injection (n=48) or ARCR without PRP (n=48). The primary outcome was the retear rate, assessed via MRI at six months. Secondary outcomes included pain (VAS), functional scores (ASES, SANE), and sleep quality (PSQI), evaluated at six and twelve months postoperatively. Overall, the study found that the retear rate in the PRP group was significantly lower than in the control group (15.2% vs. 34.1%, p = 0.037). However, there were no significant differences in functional outcomes between groups. The findings suggest that while LP-PRP reduces the retear rate, it does not provide clinically significant improvements in pain or function.
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