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Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.

OE COVID-19 EXCLUSIVE Resource Centre A Message from the Editor-in-Chief


The COVID-19 Pandemic requires the rapid identification and implementation of large-scale action. OE Best Practices will help guide MSK care in the weeks and months to come.

Best Practices

OE Best Practices for Surgeons V3.0

COVID-19 Evidence-Based Scoping Review A Unifying Report of Global Recommendations

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Best Practices

OE Best Practice for Virtual Meetings

Recommendations for transitioning to Virtual Meetings amid the COVID-19 Pandemic

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Endorsed by International Associations Worldwide

Full Report of ICM “Protocols for Resuming Elective Surgery” Available Exclusively on OrthoEvidence.


Summary of ICM “Protocols for Resuming Elective Surgery” Published on JBJS.


AIOT Releases Recommendations for 150K + Surgeons Worldwide Listing OE Best Practices as Key Resource.


Italian Orthopaedics and Traumatology Society Translates OE Best Practices Document for Members.


Canadian Orthopaedic Association Released Position Statement Referencing OE Best Practices Document.


September 10, 2022

In It for The Long Haul: Surgical Considerations for Patients with Post-COVID Conditions (Updated)

April 22, 2022

Rebuilding Better: 12 Trends for Health Care System Change Post-Covid 19

September 4, 2021

The “Long Haulers”: Long Lasting Impacts of COVID-19 on Brain Health

July 23, 2021

Vaccine Nationalism to Vaccine Equity: Global Solidarity to Eradicate COVID-19

June 11, 2021

Early Discharge: The Rise in Return to the Emergency Department after Surgery

May 21, 2021

Surgery Backlogs One Year Later: Beyond The Tipping Point

May 7, 2021

Airborne Transmission of COVID-19: New Insights

May 1, 2021

COVID-19 Crisis in India: Lessons for the World

April 23, 2021

Evaluation of COVID-19 Vaccines: Is Hesitancy for Some Vaccines Evidence-Based?

April 16, 2021

The Return of Big Stadium Events: Is the Reward Worth the Risk?

April 9, 2021

The Third Wave of COVID-19: Impact and Outcomes

April 3, 2021

Waiting for Surgery: Opioids at the Forefront, Again!

February 27, 2021

Towards Herd Immunity: Valuation of COVID-19 Vaccines

January 16, 2021

Vaccine Hesitancy: A Top 10 Threat to Global Health

November 14, 2020

(Mis)leading During a Crisis: Social Media and the Weaponisation of Dis-Information

November 7, 2020

The Promise of Big Data: Conquering COVID-19 with Data and Intelligence

October 24, 2020

Battling the Second Wave of COVID-19: How Invincible Are Young People?

October 24, 2020

Impact of COVID-19 Lockdowns in the Developing World: A Humanitarian Crisis Like No Other

October 17, 2020

Lessons Learnt from Reopening Strategies

October 10, 2020

"Randomized Trials" During the SARS-CoV2 Pandemic: What Went Wrong?

September 26, 2020

Leading Change

September 11, 2020

Novel Approaches to Acknowledge Research Contributions? “Writing” the Wrongs

September 5, 2020

Equity in Surgery: Being Diverse and Inclusive, Isn’t Enough

August 28, 2020

COVID-19 and Surgery: Are We Trading One Problem for Another?

August 14, 2020

The Rush to Find a Cure: Are We Sacrificing Quality For Speed?

August 8, 2020

Burning Out: Resilience Isn't Enough

August 1, 2020

A Vexing Virus and The Valuation of Vaccines

July 25, 2020

Health Care Heroes: Are We Asking Too Much?

July 16, 2020

Harnessing the Power of a Crisis: Will We Repeat History or Learn From It

July 2, 2020

Reaching Zero: New Zealand's Strategy in the Fight Against COVID-19

June 13, 2020

The Trouble with Testing: Navigating Uncertainty on the Road to Resuming Elective Surgeries

June 1, 2020

A Surgical Deep Freeze: Backlogs, Burden and New Beginnings

May 23, 2020

Welcome To The Jungle! Surviving Misinformation In A Crisis

May 14, 2020

The Case For, and Against “Corticosteroid Distancing” in the Management of Knee Osteoarthritis

May 6, 2020

Has the Pandemic Worsened the Epidemic? Opioid Use Disorder in Orthopaedic Patients

April 27, 2020

The Productivity Paradox - Keeping Busy During Shutdown May Be The Wrong Strategy

April 17, 2020

Rise of a New Virtual “Reality” for Orthopaedic Surgeons: Boom or Bubble?

April 7, 2020

Masks in the Fight Against COVID-19: An 'Inconvenient' Truth

View All Covid-19 Podcasts
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OrthoEvidence Partners with JBJS for a Rapid Evidence-Based Review:

Novel Coronavirus COVID-19: Current Evidence and Evolving Strategies

COVID-19 Related OE Originals

Our Covid-19 OE Originals' leverage the expertise of our in house data scientists who provide new data analyses and results to inform critical questions.


SARS-CoV-2 Omicron: What’s New in Evidence?


Omicron Updated: Key Questions Answered


The Rise of the Omicron SARS-CoV-2 Variant of Concern: Uncertainties Remain, But Readiness Is All


What Are the Long-term Outcomes for COVID-19 Survivors? A Review of Evidence


Mix-and-Match Vaccination Against COVID-19: Review of Latest Evidence


Overestimating the Treatment Effects of Molnupiravir Against COVID-19: A Deep Look from the Perspective of Stopping-Trial-Early-For-Benefits


COVID-19 Vaccine: What Do We Know About Its Efficacy and Safety in Children?


Meta-analyses Are Only As Good As The Studies They Combine: A Lesson Learned From Meta-analyses On Ivermectin Against COVID-19


COVID-19 Vaccines: Evidence-Based Answers to the 5 Most Commonly Asked Questions


OrthoEvidence. Strategies to Increase COVID-19 Vaccinations: Review of Current Evidence


The Ongoing Delta Variant Disaster: Stop the Misinformation and Follow the Evidence


Delta and Lambda SARS-CoV-2 Variants: Current Evidence


Treatment Options for COVID-19: Evidence Review for Promising Candidates


A Single-Dose of COVID-19 Vaccine May Not Protect Us from the SARS-CoV-2 Delta Variant: An Evidence Review


COVID-19 Vaccinations: Evidence for Delaying-Second-Dose and Mix-and-Match Strategies?


Treatment Options for COVID-19: Lots Have Been Tested, But Only a Few Have Evidence


COVID-19 Variants of Concern and Variants of Interest: What’s the Evidence?


AstraZeneca COVID-19 Vaccine Efficacy and Blood Clots: Let’s Talk Data


Resuming Elective Surgeries During COVID-19: Déjà vu 1 Year Later


Obesity, Diabetes Mellitus, and COVID-19: A Review of Evidence


COVID-19 Vaccines: Failure Is Not An Option


COVID-19: Vaccine Effectiveness in the Real World


COVID-19 Variants of Concern: Will There Be A Third Wave?


COVID-19: Long-Lasting Health Effects Among Survivors


COVID-19 Vaccines: What Does the Evidence Say about Delaying the Second Dose?


Mask Wearing Policy Did Not Prevent SARS-CoV-2 Infection in Community Setting Randomized Trial


Vaccines for COVID-19: Pfizer, Moderna, and AstraZeneca Race to Finish Line


Monoclonal Antibodies: Does Regeneron Have A Cure?


Remdesivir As the First FDA-approved COVID-19 Treatment: An Updated Review and Meta-analysis


Evidence For Outpatient Hip and Knee Arthroplasty: A Strategy During COVID-19


COVID-19 Vaccines: The Current Candidates in Phase III Trials


Weak Evidence for Convalescent Plasma in the Treatment of COVID-19


Corticosteroid-related Osteonecrosis: The Downstream Consequences of COVID Treatments


The Sobering Story of SARS-CoV-2 Seroprevalence: What You May Have Heard About Herd Immunity


Why Bill Gates is “Most Excited” About The Promise of Monoclonal antibodies for COVID-19: Evidence Deep Dive


Don't Believe the Hype; Remdesivir in the Treatment of COVID-19


Delivering Bad News: The Emergence of “Protector” As a New Health Care Provider Role


UPDATE 2.0: Emerging Treatments in Fight Against COVID-19


COVID-19 Delays: Patient Perspectives on Orthopaedic Surgery Postponements and Post-operative Care Limitations


Dexamethasone: New Study Shows Promising Results for COVID-19 Patients


Facts Don’t Have Feelings: Prophylaxis, treatment, and safety of hydroxychloroquine / chloroquine against COVID-19


Tele-Rehabilitation: Will it Move Us, or Just Move Away?


Vitamin D and COVID-19: Taking It Won’t Hurt, But Probably Doesn’t Help!


Caught in the COVID-19 Crossfire: Supporting Patients Facing Surgical Uncertainty


Tips for Navigating the Information Epidemic During a Crisis


UPDATE: Emerging Treatments in Fight Against COVID-19


The (R)evolution of Virtual Communication You may not love it, But Some of Your Patients Do!


Life-threatening Clots in COVID-19 Patients: Digging Deeper


Anxiety and Depression in the COVID-19 Pandemic: Are We Doing Enough?


Tumor Surgery and Research Goes On Amid O.R. Shutdowns: A Double-Edged Sword for Patients in the COVID-19 Era


Trapped at Home: The Rise in Domestic Violence During COVID-19


Emerging Treatments in Fight Against COVID-19




Cloth Masks for protection against COVID-19: MythBuster


COVID-19 Pandemic: A Global Perspective


COVID-19: Guiding surgeons through this pandemic


If we have ever needed quality and timely data to help us make critical decisions---decisions that will ultimately save lives and restore health—we need it now. The COVID-19 pandemic has generated millions of data points. We have the answers, we simply need the tools to extract the signal

Mohit Bhandari MD, PhD, FRCSC

Professor and University Scholar, McMaster University

Hamilton, Ontario, Canada

All elective surgeries (such as total knee replacement) have been postponed indefinitely, while surgeons using full protective gear will perform high-risk aerosol-generating procedures (such as extensive burring/drilling). A geriatric hip fracture case was actually confirmed to be COVID positive after her hemiarthroplasty, fortunately, none of the medical staff was infected.

Samuel Ling, MD

Assistant Professor of Orthopaedics & Traumatology

The Chinese University of Hong Kong

Hong Kong, China

Currently, as on 17/03/2020, there have been 4 deaths reported in India, and the number of infected cases in India have reached 149. Pune has reported 16 cases already. In my opinion, we are in the 2nd phase of this pandemic and there is a possibility that further spread may occur and the scenario may worsen if we enter the 3rd phase wherein communities may get infected.

Parag Sancheti, MD, FRCS (Ed), MS, DNB, MCh ,Ph.D

Professor & Chairman Sancheti Institute

For Orthopaedics & Rehabilitation

Pune, India

It is crucial to enhance international communication and collaboration to fight the disease. The key message is to alert the mass of common people, globally, to do their best to prevent infection. I estimate that the pandemic of COVID-19 might end in June this year. However, if not all the countries take this seriously and put in action interventions, the anticipated turning point of its pandemic will postpone.

Nanshan Zhong, MD

Professor, Chinese epidemiologist and

pulmonologist who discovered

the SARS coronavirus in 2003

The steady declination of cases in recent two weeks in China has been credited to the effective national interventions. We need to keep the data open and transparent, enhance sensitivity of early nucleic acid testing is important. Any intervention strategies should be evidence-based. Policy-makers should take actions based on the local public health experts’ opinion. Community isolation is probably inevitable. Every area should try efforts to find the best model fitting to local condition. Lastly, it is valuable to enhance international communication of researches and experiences on the pandemic control.

Guang Zeng, MD

Professor, Chinese Epidemiologist

Chief Scientist from the Chinese Center for Disease

Control and Prevention (Chinese CDC)

In Mexico, COVID -19 cases are just starting to climb, with around 120 cases reported so far. Streets are empty and misinformation is climbing. Our politicians are not doing their part- only thinking about re-election maneuvers. The healthcare system is preparing for the worst-case scenarios and are trying to learn from other countries experience. Young doctors are ready to fight, while older doctors try to dig into there experience to fight against this virus. We as a society have to be brave and strong to be able to get a victory around this scary situation

Edmundo Berumen, MD, FRCSC

Orthopaedic Surgeon

University of Mexico

...the Division of Trauma at R Adams Cowley Shock Trauma Center are into our second week of significant changes to mitigate the impact of COVID-19...we conduct our daily Morning Report virtually—each member of the team in a different office. Clinically, we have split our service into three teams working 3 days at a time. We are making all these changes to prevent the spread of the novel coronavirus within the team, and most importantly, to ensure we have sufficient personnel once members get infected. Will this work? The uncertainty is quite unnerving.

Gerard Slobogean, MD, MPH, FRCSC

Associate Professor, Department of Orthopaedics

University of Maryland

With time and implementation of a lot of drastic policies & stringent measures, Hong Kong has been able to prevent major outbreak in the community....gradual resumption of elective surgeries, increasing outpatient attendance, more interactive educational activities, and progressive normalisation of all the research works have been coming back gradually since early March 2020. Having said that, because of the outbreak in America & Europe in the recent few weeks, Hong Kong is again at threat of another wave because of infected cases from overseas...

Professor YUNG Shu Hang Patrick JP

Chairman, Department of Orthopaedics & Traumatology, Faculty of Medicine, The Chinese University of Hong Kong

President, Asian Federation of Sports Medicine

In consequence of COVID-19, the orthopaedic community has come to a standstill in Canada, with most centres acting responsibly by cancelling all elective surgery and nonessential clinical visits to limit interactions…. Throughout Canada, responsible orthopaedic surgeons are exclusively treating urgent cases and adopting strict safety protocols to avoid further spread of COVID-19 while delivering emergency care… we commend your efforts and are grateful for your contributions.

Mark Glazebrook, MD, FRCSC, PhD


Canadian Orthopaedics Association

The COVID-19 is also increasing in Germany with a current number of infected cases around 58.000. Fortunately, the mortality rate in Germany is with 0.77% signifcantly lower compared to other countries. One reason for the lower mortality might be the fact, that the German government started early with preventive policies to avoid the corona virus spread. In Germany, the vast majority of hospitals have postponed elective surgeries, interventions and admissions in order to have free capacity for COVID-19 patients. In our arthroplasty center, we only perform cases such as periprosthetic fractures, dislocations of the hip prosthesis, periprosthetic joint infections or acute spinal disorders.

Mustafa Citak MD, PhD, CPT

Hamburg, Germany

As of March 28, there are 1909 COVID cases in Chile with 6 deceased people. The highest percentage of cases (56.8%) is concentrated in the Metropolitan Region… In conversation with some orthopedic colleagues, only emergency surgeries are being performed at various healthcare centers. All elective surgeries have been postponed until further notice.... Also, in the centers where I work, the teams have been divided so that one group is active and the other group is in preventive quarantine for 2 weeks. At the end of this period we will make the respective change.

Fernando Vargas, MD

Foot and Ankle Surgeon

Clinica Santa Maria

Hospital Mutual de Seguridad

In Amsterdam the COVID19 situation is still under control. The hospitals are preparing for a worst case scenario. All elective cases are postponed. OR staff is trained to use ventilators in ICU setting. The OLVG hospital launched a smartphone app to monitor inhabitants of Amsterdam who have minor symptoms. In this way the hospital is able to gauge the situation and is prepared to scale up. All residents - including ortho - are taking shifts to answers questions from app users and give advise. Never waste a good crisis. This gives us opportunities to speed up digital consultations with patients. We hope to find smart solutions working towards a digital hospital.

Rudolf W. Poolman MD PhD

Orthopedic Surgeon-Scientist

Leiden University Medical Centre

Leiden, Netherlands

SARS-CoV-2 coronavirus has crossed all borders. In Spain, the coronavirus is growing exponentially. Radical measures that the situation demanded have been taken late. Data from 7 April report more than 140,511 confirmed Covid-19 cases and more than 13,897 deaths. Tests are not done on all symptomatic patients, so it is considered that only 20% of cases are being diagnosed. Around 12% of Health personnel has been infected. Since March 14 the radical measures were taken and confinement is rigorously controlled, probably this is the reason why new infected cases and new deaths are decreasing. Data that should be taken with caution.

Ernesto Guerra

Vall d´Hebron University Hospital

Barcelona, Spain

  • Coronavirus originating from Wuhan, China in December, 2019
  • Can be transmitted directly or indirectly by asymptomatic and presymptomatic persons
  • As of March 26, 2020: 462,684 infected; 20,834 deaths
  • Most common symptoms are fever and cough. Presenting on avg 5.1 days after infection, with 97.5% presenting by 11.5 days
  • Hygiene, social distancing, and isolation are most recommended mitigation measures. Public and private closures are recommended in specific cases
  • 88.2% have abnormalities on chest x-ray
  • Mortality rate estimates are approximately 3.9% in confirmed cases. Comorbidities most likely linked to mortality are cardiovascular disease and diabetes
  • 20% of cases are severe or critical
  • Social distancing seems effective in flattening the curve from evidence of the 1918 influenza pandemic
  • A second wave was seen in both SARS and the 1918 influenza epidemics following relaxation of containment methods