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You are viewing the most viewed ACE Reports by Primary Care Physicians over the last 30 days in all specialties.
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Micro-fragmented Adipose Tissue Versus Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis
①
Synopsis:
One hundred and eighteen patients with symptomatic knee osteoarthritis were randomized to receive either intra-articular micro-fragmented adipose tissue injections (MF-AT; n=59) or platelet-rich plasma injections (PRP; n=59).The primary outcome of this trial was the change in International Knee Documentation Committee (IKDC) scores and pain subscale of the Knee Osteoarthritis Outcome Score (KOOS) from baseline to 6 months.Other outcomes such as KOOS subscales for functional improvement, EuroQol visual analog scale (EQ-VAS), EuroQol 5 Dimensions (EQ-5D), and Visual Analog Scale (VAS) for pain at 3, 6, 12, and 24 months.MRI findings using the Whole-Organ Magnetic Resonance Imaging (WORMS) score was also assessed.Statistically significant improvements in all clinical scores were apparent in the MF-AT group, except for EQ-VAS scores. IKDC and KOOS...
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Level 1 RCT
7%
①
Synopsis:
Five randomized controlled trials (189 patients) comparing platelet-rich plasma (PRP) against conservative treatment for chronic Achilles tendinopathy were included in this systematic review and meta-analysis.Outcomes of interest included the Victorian Insitute of Sport Assessment (VISA-A) score, pain during activity on a Visual Analog Scale (VAS), and Achilles tendon thickness.VISA-A scores at 6 weeks favored the PRP group.Tendon thickness also favored the PRP group. All other outcomes...
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Level 1 Meta Analysis
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Effect of Physical Exercise on Knee Muscle Function in Postmenopausal Women with Knee Osteoarthritis
①
Synopsis:
Five randomized controlled trials with 286 postmenopausal women with knee osteoarthritis were included in this systematic review and meta-analysis comparing physical exercise interventions, including aquatic and aerobic exercise, to control groups.Pooled outcomes included physical function, pain, stiffness, knee muscle function, and quality of life.The meta-analysis found significant improvements in physical function for the exercise group, with moderate effect sizes, though no significant differences were observed in pain or stiffness outcomes. Overall, the findings...
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Level 1 Meta Analysis
4%
①
Synopsis:
192 patients with unilateral, symptomatic knee osteoarthritis were randomized to receive 3 weekly intra-articular injections of leukocyte-rich platelet-rich plasma (n=96) or leukocyte-poor platelet-rich plasma (n=96).The primary outcome of interest was the International Knee Documentation Committee (IKDC) score at 12 months.Secondary outcomes of interest included the Knee Injury and Osteoarthritis Outcomes Score (KOOS) sub-scales, the Tegner scale for activity/sporting level, and Euro-QoL Visual Analog Scale (EQ-VAS) for quality of life. No significant differences...
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Level 1 RCT
4%
①
Synopsis:
3 studies with 322 patients undergoing hip arthroscopy without dysplasia or generalized ligamentous laxity were included in this systematic review and meta-analysis comparing capsular repair to no repair.Pooled outcomes of interest included patient-reported outcome measures (PROMs) at 6 months and 2 years, including the modified Harris Hip Score (mHHS), Hip Outcome Score–Activities of Daily Living (HOS-ADL), and Hip Outcome Score–Sport-Specific Subscale (HOS-SSS). Pooled results indicated...
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Level 1 Meta Analysis
2%
②
Synopsis:
351 patients with a meniscus tear and knee osteoarthritis (OA) were randomized to either undergo arthroscopic partial meniscectomy (APM) followed by a physical therapy program or physical therapy alone, in order to compare clinical and functional outcomes. Following treatment over a 12 month period, all patients improved similarly in WOMAC physical-function score, KOOS pain score, and SF-36 physical-activity score.
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Author verified Level 2 RCT
2%
②
Synopsis:
52 family doctors were randomized to provide their female patients (272 female patients in total), who screened positive for intimate partner violence (IPV), with either counselling sessions or give them resource cards and provide usual care, in order to compare the quality of life, safety planning and behaviours, and mental health status between the women).Following 12 months, results indicated that counselling from a family doctor did not improve the quality of life, safety planning and behaviours, mental health, anxiety symptoms, or comfort to discuss fears in women. Patients, who received...
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Author verified Level 2 RCT
2%
Similar Outcomes with Volar-Plate Fixation vs Cast Immobilization in Elderly Wrist Fracture Patients
①
Synopsis:
One hundred and sixty-six patients who sustained displaced distal radius fractures were randomized to undergo an open reduction and internal fixation procedure using a volar-locking plate (VLP; n=81) or conservative management through closed reduction and cast immobilization (n=85).The primary outcome of interest was pain and function measured using the Patient-Rated Wrist Evaluation (PRWE) at 12 months post-treatment. Results revealed that...
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Level 1 RCT
2%
①
Synopsis:
Sixty patients undergoing unilateral primary TKA were randomized to receive surgery with a handheld semi-active robot (n=32) or a control group without robotic assistance (n=28).The primary outcomes of interest were postoperative mechanical alignment, joint line deviation and prosthesis rotation.The robotic group demonstrated improved overall mechanical alignment and reduced joint line deviation compared to the control group. No differences in...
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Level 1 RCT
2%
①
Synopsis:
141 patients undergoing total knee arthroplasty were randomized to receive either a cementless implant (n=76) or a cemented implant (n=65).Outcomes of interest included Oxford Knee Score (OKS), Knee Society Function Score, Forgotten Joint Score (FJS), percentage of normal knee, patient satisfaction, incidence of revision, and the incidence of reoperation.Outcomes were assessed at 2 and 6 years post-operation.There were no differences in all outcomes at 2 and 6 years except for patient satisfaction which was significantly better in the cementless group. The rate of...
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Level 1 RCT