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You are viewing the most viewed ACE Reports by Primary Care Physicians over the last 30 days in all specialties.
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5%
①
Synopsis:
One hundred five patients with clinically diagnosed knee osteoarthritis were randomized to receive a 6-week internet-based exercise and education program (n=48) or routine self-management care (n=57).The primary outcome of interest was change in self-reported knee pain using a numerical rating scale at 6 weeks.Secondary outcomes included physical function tests (30-second sit-to-stand, Timed Up-and-Go), WOMAC subscales (pain, stiffness, physical function), muscle strength, and quantitative sensory testing.Outcomes were assessed at baseline and 6 weeks.Overall, the results of the study revealed a significantly greater improvement in pain, function, and hamstring strength in the internet-based intervention group compared to usual care. These findings suggest...
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Level 1 RCT
5%
①
Synopsis:
Five randomized controlled trials (189 patients) comparing platelet-rich plasma (PRP) against conservative treatment for chronic Achilles tendinopathy were included in this systematic review and meta-analysis.Outcomes of interest included the Victorian Insitute of Sport Assessment (VISA-A) score, pain during activity on a Visual Analog Scale (VAS), and Achilles tendon thickness.VISA-A scores at 6 weeks favored the PRP group.Tendon thickness also favored the PRP group. All other outcomes...
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Level 1 Meta Analysis
5%
①
Synopsis:
Fifty-one college students with chronic patellar tendinopathy were randomized to receive either combined heavy slow resistance (HSR) training and high-dose therapeutic ultrasound (TUS) (n=17), HSR alone (n=17), or TUS alone (n=17).The primary outcome of interest was the VISA-P score.Secondary outcomes included VAS pain scores, Y-Balance Test, Modified Thomas Test, maximum isometric muscle strength, horizontal jump distance, and musculoskeletal ultrasound measures.Outcomes were assessed at baseline, post-intervention (8 weeks), and at 16 weeks for VISA-P.Overall, the results of the study revealed that the combined group demonstrated the greatest improvement in VISA-P scores, pain reduction, quadriceps flexibility, and muscle strength. The findings suggest...
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Level 1 RCT
3%
②
Synopsis:
106 patients with adhesive capsulitis were randomized to one of three groups to determine which mode of conservative therapy - corticosteroid injections with distension, corticosteroid injections only, or treatment-as-usual (verbal education, use of other conservative therapy) - was associated with the greatest improvement in shoulder pain, function, and range of motion on the short-term (4 and 8 weeks) and long-term (12 months).Results demonstrated that patients in both corticosteroid injection intervention groups had significant improvements in pain, function, abduction, internal rotation, and external rotation when compared to the usual treatment group when assessed at 4 and 8 weeks. Long-term improvements in...
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Level 2 RCT
3%
Synopsis:
Fifty-seven patients with symptomatic radiographically confirmed knee osteoarthritis were randomized to receive either intra-articular PRP (n=29) or CS (n=28).The primary outcomes of interest were functional outcomes measured by the WOMAC and KOOS scores.Secondary outcomes included pain measured by the VAS and the achievement of minimally clinically important differences (MCID) in WOMAC and KOOS.Outcomes were assessed at baseline, 6 weeks, and 3 months.Overall, the results revealed that CS demonstrated superior functional outcomes, with lower WOMAC scores (p=0.02) and higher KOOS scores (p=0.01) at 3 months compared to PRP.The VAS scores were similar between groups (p=0.73). These findings suggest...
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Conference Report
1%
①
Synopsis:
Four randomized controlled trials were selected for inclusion in this meta-analysis which compared results in hip osteoarthritis treatment between platelet-rich plasma injections and hyaluronic acid injections.Data on patient-reported pain and function scores were pooled at 2, 6 and 12 months post-injection. The only significant...
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Level 1 Meta Analysis
1%
②
Synopsis:
41 patients including 48 knees with Kellgren-Lawrence grade II-III osteoarthritis were randomized to intraarticular injection therapy with either platelet-rich plasma or corticosteroid (methylprednisolone acetate 40mg).Patients were assessed for outcome on the Knee Injury and Osteoarthritis Outcome Score (KOOS), pain on a visual analog scale, performance on a 20-metre walk test, knee range of motion in flexion, and flexion contracture after 2 and 6 months following injection.Findings demonstrated significantly favourable results in the PRP group compared to the CS group for changes in four out of five KOOS scales, VAS pain scores, and 20-metre walk test times. Knee range of...
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Level 2 RCT
1%
①
Synopsis:
192 patients with knee osteoarthritis were randomized to three weekly intraarticular injections with either platelet-rich plasma or hyaluronic acid.The focuse of the current study was outcome after 2 and 5 years following treatment.Results for clinical outcome on the International Knee Documentation Committee (IKDC) subjective score, the EuroQoL 5-dimensions (EQ-5D) and the Tegner activity scale demonstrated no significant differences between the PRP group and HA group at 2 or 5 years.Within the first 2 years of treatment, rate of reintervention, including either repeat injection therapy or surgery, was significantly lower in the PRP group compared to the HA group. However, at 5...
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Level 1 RCT
1%
Synopsis:
99 patients with a partial-thickness rotator cuff tear or rotator cuff tendinopathy were randomized to injection therapy with either a platelet rich plasma injection or corticosteroid injection.Patients were assessed for outcome on a visual analog scale for pain, the Western Ontario Rotator Cuff Index, the American Shoulder and Elbow Surgeons (ASES) score, and incidence of patients who progressed to operative treatment. Results demonstrated significantly...
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Conference Report
1%
①
Synopsis:
Patients with mild to moderate knee osteoarthritis face a range of treatment options, without any clear evidence on which options are most effective.Among injectable therapies, platelet-rich plasma is a relatively new option which has had mixed evidence to date.Some previous studies have compared PRP to hyaluronic acid (HA), but with differing numbers of injections in each group.In this study, the authors performed a meta-analysis of studies which provided PRP and HA injections in a 1:1 ratio. They found that...
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Level 1 Meta Analysis