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You are viewing the most viewed ACE Reports by Primary Care Physicians over the last 30 days in all specialties.
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①
Synopsis:
Seventy-nine patients with greater trochanteric pain syndrome unresponsive to conservative treatment were randomized to receive a single ultrasound-guided injection of leukocyte-rich platelet-rich plasma (n=39) or saline placebo (n=40).The primary outcome of interest was the iHOT-12 score.Secondary outcomes included VAS for pain, EQ-5D index, EQ-5D VAS, and mHHS scores.Outcomes were assessed at 3, 6, and 12 months.Overall, the results of the study revealed no significant differences in any outcome measures between the PRP and placebo groups at any follow-up point. This suggests that...
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Level 1 RCT
1%
①
Synopsis:
One hundred five patients with clinically diagnosed knee osteoarthritis were randomized to receive a 6-week internet-based exercise and education program (n=48) or routine self-management care (n=57).The primary outcome of interest was change in self-reported knee pain using a numerical rating scale at 6 weeks.Secondary outcomes included physical function tests (30-second sit-to-stand, Timed Up-and-Go), WOMAC subscales (pain, stiffness, physical function), muscle strength, and quantitative sensory testing.Outcomes were assessed at baseline and 6 weeks.Overall, the results of the study revealed a significantly greater improvement in pain, function, and hamstring strength in the internet-based intervention group compared to usual care. These findings suggest...
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Level 1 RCT
1%
①
Synopsis:
One hundred patients with chronic midportion Achilles tendinopathy were randomized to receive either exercise therapy combined with ultrasonography-guided corticosteroid injection (n=48) or exercise therapy with placebo injection (n=52).The primary outcome was improvement in the Victorian Institute of Sport Assessment–Achilles (VISA-A) score at 6 months.Secondary outcomes included tendon thickness, pain during activity and in the morning (measured by VAS), and global assessment of treatment response.Outcomes were assessed at baseline and 1, 2, 3, 6, 12, and 24 months.Overall, the results revealed that the corticosteroid group showed a significantly greater improvement in VISA-A scores at 6 months, accompanied by improved tendon morphology and early symptom relief, with no increase in adverse events. These findings suggest...
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Level 1 RCT
1%
①
Synopsis:
Three hundred twenty-one patients with degenerative meniscal tears were randomized to receive arthroscopic partial meniscectomy (n=159) or exercise-based physical therapy (n=162).The primary outcome of interest was patient-reported knee function assessed by the International Knee Documentation Committee (IKDC) questionnaire.Secondary outcomes included radiographic progression of knee osteoarthritis, symptomatic OA, pain during activities, physical functioning (KOOS-PS), and quality of life.Outcomes were assessed at multiple time points up to 5 years.Overall, the results of the study revealed that physical therapy was noninferior to surgery for knee function, with no clinically meaningful differences in OA progression or other secondary outcomes. These findings suggest...
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Level 1 RCT
1%
①
Synopsis:
Five randomized controlled trials (189 patients) comparing platelet-rich plasma (PRP) against conservative treatment for chronic Achilles tendinopathy were included in this systematic review and meta-analysis.Outcomes of interest included the Victorian Insitute of Sport Assessment (VISA-A) score, pain during activity on a Visual Analog Scale (VAS), and Achilles tendon thickness.VISA-A scores at 6 weeks favored the PRP group.Tendon thickness also favored the PRP group. All other outcomes...
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Level 1 Meta Analysis
1%
②
Synopsis:
106 patients with adhesive capsulitis were randomized to one of three groups to determine which mode of conservative therapy - corticosteroid injections with distension, corticosteroid injections only, or treatment-as-usual (verbal education, use of other conservative therapy) - was associated with the greatest improvement in shoulder pain, function, and range of motion on the short-term (4 and 8 weeks) and long-term (12 months).Results demonstrated that patients in both corticosteroid injection intervention groups had significant improvements in pain, function, abduction, internal rotation, and external rotation when compared to the usual treatment group when assessed at 4 and 8 weeks. Long-term improvements in...
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Level 2 RCT
1%
①
Synopsis:
One hundred twenty-eight patients with sciatica lasting 4 to 12 months due to lumbar disc herniation were randomized to receive either microdiscectomy (n=64) or 6 months of standardized nonoperative care (n=64).The primary outcome was leg pain intensity at 6 months.Secondary outcomes included back pain, Oswestry Disability Index (ODI), SF-36 quality-of-life scores, employment status, and treatment satisfaction, assessed at multiple time points up to 12 months.Overall, the results of the study revealed that microdiscectomy led to a significantly greater reduction in leg pain at 6 months and consistent improvements in secondary outcomes. These findings suggest...
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Level 1 RCT
1%
①
Synopsis:
Two hundred forty patients with chronic midportion Achilles tendinopathy were randomized to receive either a single platelet-rich plasma (PRP) injection (n=121) or a sham subcutaneous dry needle injection (n=119).The primary outcome was the VISA-A score at 6 months, which assesses pain, function, and activity limitations related to Achilles tendinopathy.Secondary outcomes included the VISA-A score at 3 months, pain via visual analog scale (VAS), and health-related quality of life using EQ-5D-5L at multiple follow-up points (2 weeks, 3 months, and 6 months).Overall, the results of the study revealed no significant difference between the PRP and sham groups in any of the measured outcomes, including the primary VISA-A score at 6 months. These findings suggest...
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Level 1 RCT
1%
①
Synopsis:
Fifty-one college students with chronic patellar tendinopathy were randomized to receive either combined heavy slow resistance (HSR) training and high-dose therapeutic ultrasound (TUS) (n=17), HSR alone (n=17), or TUS alone (n=17).The primary outcome of interest was the VISA-P score.Secondary outcomes included VAS pain scores, Y-Balance Test, Modified Thomas Test, maximum isometric muscle strength, horizontal jump distance, and musculoskeletal ultrasound measures.Outcomes were assessed at baseline, post-intervention (8 weeks), and at 16 weeks for VISA-P.Overall, the results of the study revealed that the combined group demonstrated the greatest improvement in VISA-P scores, pain reduction, quadriceps flexibility, and muscle strength. The findings suggest...
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Level 1 RCT
<1%
①
Synopsis:
Three hundred sixty-three patients with recent unilateral total knee arthroplasty were randomized to receive outpatient rehabilitation with a recumbent bike (control, n=92), a body weight–adjustable treadmill (n=91), a PENS device (n=90), or a combination of both modalities (n=90).The primary outcomes were the AM-PAC basic mobility score and the 6-minute walk test.Secondary outcomes included use of assistive devices, pain medication, and weight-bearing status.Outcomes were assessed at baseline, monthly, and on discharge, approximately 60 days after therapy initiation.Overall, the results of the study revealed no statistically significant differences in functional mobility or walking distance across all groups at discharge (AM-PAC scores: P = .99; walk distance: P = .60). These findings suggest...
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Level 1 RCT