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6%
Synopsis: Sixty patients with plantar fasciitis were randomized to receive an ultrasound-guided injection of platelet-rich plasma (n=30) or autologous blood product.The outcomes of interest included pain on a Visual Analog Scale (VAS) and the Foot and Ankle Disability Index (FADI), measured at 1, 3 and 6 months. Results revealed no... Read More »
Level 1 RCT
6%
Synopsis: One hundred and twenty patients with adhesive capsulitis were randomized to receive up to 3 weekly corticosteroid injections into the coracohumeral ligament and inferior glenohumeral capsule (CHL + IGHC; n=60) or via the posterior glenohumeral recess (PGHR; n=60).The outcomes of interest included pain intensity on a Visual Analog Scale (VAS) and passive shoulder range of motion in abduction; external rotation; and internal rotation, assessed 2 and 4 months after the first injection.Results showed improvements in both groups over time, however, the improvement in pain scores and all range of motion outcomes were significantly better in the CHL+IGHC group vs. Read More »
Level 1 RCT
5%
Synopsis: Eight randomized trials containing a total of 2096 patients with osteoarthritis were included in this systematic review and meta-analysis comparing topical and oral non-steroidal anti-inflammatory drugs (NSAIDs).Pooled outcomes of interest included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and stiffness sub-scores, pain on a Visual Analog Scale (VAS), and the odds of skin adverse reactions, gastrointestinal adverse reactions, and any adverse event.The results of the meta-analysis found no differences in pooled WOMAC pain, WOMAC stiffness, VAS pain scores, and odds of any adverse event between the two formulations. The pooled odds... Read More »
Level 1 Meta Analysis
4%
Synopsis: Sixty-four patients with de Quervain's tenosynovitis were randomized to receive a local injection of ketorolac (n=31) or triamcinolone acetonide (n=33).Outcomes of interest included pain scores on a Visual Numeric Rating Scale (VNRS), the Disabilities of the Arm, Shoulder and Hand (DASH) score, grip strength and pinch strength, and the need for additional injection, assessed at 6 weeks follow up.The results revealed superior pain scores, DASH scores, and grip strength outcomes in the triamcinolone group vs.the ketorolac group. The need for... Read More »
Level 1 RCT
3%
Synopsis: One hundred knee osteoarthritis patients were randomized to receive 3 intra-articular injections of highly-purified polynucleotides plus hyaluronic acid (n=50) or hyaluronic acid alone (n=50).This study was a 2 year follow up to a previously published 1 year follow up interim analysis.The primary outcome of interest was Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain sub-score.Secondary outcomes of interest included WOMAC stiffness, function, "walking on flat surface", and total scores, and Knee Society Score (KSS) total and pain scores scores.Results revealed no significant difference in WOMAC pain, stiffness, "walking on a flat surface", or function scores at 24 months.WOMAC total scores were significantly in favour of the combination group at 24 months. No significant difference... Read More »
Level 1 RCT
3%
Synopsis: 111 patients with idiopathic carpal tunnel syndrome were randomized to receive an 80mg local steroid injection (methylprednisolone), 40mg local steroid injection, or placebo injection.Outcomes of interest included time to and rate of subsequent surgical intervention, Short-Form 36 (SF-36) bodily pain scores, treatment satisfaction, symptom severity score, and Quick Disability of the Arm, Shoulder and Hand (QuickDASH) scores.Outcomes were assessed at 5 years follow up.Local steroid injection was found to significantly reduce the rate of surgical intervention and delay time to surgery compared to placebo. No significant differences... Read More »
Level 1 RCT
3%
Synopsis: Fifty female recreational runners with medial tibial stress syndrome (shin splints) were randomized to receive an 18-week multimodal intervention program (icing, ankle stretching and strengthening, extracorporeal shockwave therapy) plus the use of arch support foot orthoses (n=25) or a sham orthoses (n=25).Outcomes of interest included pain intensity, condition severity, perceived treatment effect, and the Short-Form 36 (SF-36) quality of life questionnaire.Results revealed significantly greater improvement in pain intensity, condition severity, perceived treatment effect, and SF-36 physical function and bodily harm sub-scores in the foot orthoses group vs. Read More »
Level 1 RCT
2%
Synopsis: Twenty-eight patients who were diagnosed with chronic neck pain with a depressed scapula were randomized to either the active scapular correction group (n=14) or control (n=14).The outcomes of this trial were to assess cervical range of motion, neck pain with cervical rotation, and pressure pain threshold (PPT) over the upper trapezius muscle between the two study arms. The results of... Read More »
Level 1 RCT
2%
Synopsis: 316 patients with non-acute anterior cruciate ligament (ACL) injuries and persistent instability were randomized to receive immediate surgery (n=156) or rehabilitation (n=160).The primary outcome of interest was the Knee Injury and Osteoarthritis Outcome Score - 4 domain (KOOS4).Secondary outcomes of interest included quality of life measures, the Tegner activity score, resource use, complications and patient satisfaction.Primary follow-up occurred at 18 months.The results of this study found that, whilst both groups showed improvement, patients who received immediate surgery had significantly better knee function, pain, patient satisfaction, and Tegner activity scores compared to the rehabilitation group.Surgery was found to have a 72% chance of being cost-effective vs. Read More »
Author verified Level 1 RCT
2%
Synopsis: Thirty-three patients with low back pain or sacroiliac joint pain were included in this crossover randomized trial assessing the effect of a Serola Sacroiliac belt on pain and functional impairment after 5 days of strenuous repeated manual labour.Patients either performed 5 days of manual labour tasks with the belt followed by 5 days of manual labour tasks without, or vice-versa.Outcomes of interest included Numeric Rating Scale (NRS) pain scores, spine and thigh discomfort on a Nordic Musculoskeletal Questionnaire (NMQ), and flexion relaxation phenomenon testing, measured after the completion of each intervention period.Whilst both groups demonstrated progression in symptoms, the results found that Serola belt usage resulted in less progression of NRS back pain compared to the control group. No other differences... Read More »
Level 1 RCT