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5%
Synopsis: One hundred and nineteen patients with insertional Achilles tendinopathy were randomized to received extracorporeal shockwave therapy with eccentric exercise (ESWT +EE) (n=58) or eccentric exercise (EE) and sham therapy (n=61).The primary outcome was function measured by the Victorian Institute of Sports Assessment-Achilles questionnaire (VISA-A).Secondary outcomes of interest included pain scores, the Foot and Ankle Outcome Score (FAOS), the Short Form Health Survey (SF-12), recurrence and failure of treatment.Both groups demonstrated significant improvements from baseline.No differences in the VISA-A, FAOS or SF-12 were found at any time point between groups. The EWST+EE group... Read More »
Level 1 RCT
5%
Synopsis: 192 patients with unilateral, symptomatic knee osteoarthritis were randomized to receive 3 weekly intra-articular injections of leukocyte-rich platelet-rich plasma (n=96) or leukocyte-poor platelet-rich plasma (n=96).The primary outcome of interest was the International Knee Documentation Committee (IKDC) score at 12 months.Secondary outcomes of interest included the Knee Injury and Osteoarthritis Outcomes Score (KOOS) sub-scales, the Tegner scale for activity/sporting level, and Euro-QoL Visual Analog Scale (EQ-VAS) for quality of life. No significant differences... Read More »
Level 1 RCT
3%
Synopsis: One hundred five patients with clinically diagnosed knee osteoarthritis were randomized to receive a 6-week internet-based exercise and education program (n=48) or routine self-management care (n=57).The primary outcome of interest was change in self-reported knee pain using a numerical rating scale at 6 weeks.Secondary outcomes included physical function tests (30-second sit-to-stand, Timed Up-and-Go), WOMAC subscales (pain, stiffness, physical function), muscle strength, and quantitative sensory testing.Outcomes were assessed at baseline and 6 weeks.Overall, the results of the study revealed a significantly greater improvement in pain, function, and hamstring strength in the internet-based intervention group compared to usual care. These findings suggest... Read More »
Level 1 RCT
3%
Synopsis: Five randomized controlled trials (189 patients) comparing platelet-rich plasma (PRP) against conservative treatment for chronic Achilles tendinopathy were included in this systematic review and meta-analysis.Outcomes of interest included the Victorian Insitute of Sport Assessment (VISA-A) score, pain during activity on a Visual Analog Scale (VAS), and Achilles tendon thickness.VISA-A scores at 6 weeks favored the PRP group.Tendon thickness also favored the PRP group. All other outcomes... Read More »
Level 1 Meta Analysis
2%
Synopsis: 84 patients over 18 years of age with isolated rib fractures were included in this single center, prospective, placebo controlled, double blind trial.Patients were randomly allocated to receive either 10% lidocaine spray (LS; n=29), etofenamate spray (ES; n=28) or placebo spray (PS; n=27).The primary outcome of interest was pain intensity measured using a numerical rating scale (NRS) at baseline, and 15, 30, 60 and 120 minutes.Other outcomes of interest included rescue medication requirements and adverse events.Study findings suggest that all three groups demonstrated similar NRS scores, with no significant difference in pain reduction found at any timepoint.The maximum reduction was seen in the LS group between baseline and 120 minutes, however this difference was not statistically significant.It was also seen that the need for rescue medication was lowest in the LS group; a difference that was found to be clinically significant but not statistically significant. Importantly, only one... Read More »
Author verified Level 1 RCT
2%
Synopsis: 80 patients with distal radius fractures were randomized to receive either a 4-week (n=40) or a 6-week immobilization program.The primary outcome of interest was Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) scores at one year.Secondary outcomes of interest included QuickDASH scores at 3 and 6 months, incidence of adverse events, and range of motion in radial and ulnar deviation, dorsiflexion, and palmar flexion.All outcomes were comparable between the two groups at all time points. Therefore, a shorter... Read More »
Level 1 RCT
2%
Synopsis: 106 patients with adhesive capsulitis were randomized to one of three groups to determine which mode of conservative therapy - corticosteroid injections with distension, corticosteroid injections only, or treatment-as-usual (verbal education, use of other conservative therapy) - was associated with the greatest improvement in shoulder pain, function, and range of motion on the short-term (4 and 8 weeks) and long-term (12 months).Results demonstrated that patients in both corticosteroid injection intervention groups had significant improvements in pain, function, abduction, internal rotation, and external rotation when compared to the usual treatment group when assessed at 4 and 8 weeks. Long-term improvements in... Read More »
Level 2 RCT
2%
Synopsis: 12,211 patients from 21 trauma centers in the United States and Canada were included in this non-inferiority randomized trial comparing aspirin (n=6,101) and low molecular-weight heparin (n=6110).The primary outcome of interest was death by any cause at 90 days.Secondary outcomes of interest included the risk of thromboembolic events (pulmonary embolism; deep-vein thrombosis), cause-specific death, bleeding & wound complications, and the rate of infection.Aspirin was found to be non-inferior to low molecular-weight heparin with respect to the primary outcome of death by any cause. No differences in... Read More »
Level 1 RCT
2%
Synopsis: One hundred patients with isolated traumatic meniscal tears were randomized to receive either arthroscopic partial meniscectomy (n=49) or standardized physical therapy (n=51), with the option for delayed arthroscopic partial meniscectomy after three months.The primary outcome was the IKDC score at 24 months, which assesses knee symptoms, function, and ability to participate in sports.Secondary outcomes included KOOS, NRS pain, Lysholm, WOMET, Tegner activity level, and satisfaction with knee function.Follow-up assessments were conducted at multiple time points up to 24 months.Overall, both groups demonstrated clinically relevant improvements in IKDC scores, but there was no significant difference between the groups at 24 months. The study suggests... Read More »
Level 1 RCT
1%
Synopsis: Sixty-four patients suffering from adhesive capsulitis (AC) were randomized to receive a single ultrasound-guided platelet-rich plasma (PRP) injection (n=32) or conventional physiotherapy (CP) consisting of shortwave diathermy treatment and exercise (n=32).Outcomes of interest included pain on a Visual Analogue Scale (VAS), function using the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire, and range of motion (i.e.flexion, abduction, external rotation), which were all evaluated at 1, 3 and 6 weeks post-treatment.Furthermore, the consumption of acetaminophen was recorded at 0-1 week, 1-3 weeks, and 3-6 weeks follow-up.Results revealed no statistical significant differences in all outcomes between the PRP and CP groups (p>0.05 for all).Yet, all outcomes did statistically significantly improve with time in both groups(p<0.001 for all).The consumption of acetaminophen was statistically significantly reduced in the PRP group vs CP group at 0-1 weeks (p=0.005), 1-3 weeks (p=0.005), and 3-6 weeks (p=0.002) follow-up. Read More »
Level 1 RCT