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9%
Synopsis: Twenty-four patients with hamstring shortness were randomized to receive either a self-myofascial release program with a foam roller (n=12) or no intervention (control) (n=12).The primary outcome of this trial was to determine the effect of using a foam roller on the isokinetic hamstring-to-quadriceps strength ratio and range of motion after 8 weeks.The results of this trial showed significant improvements in the range of motion in the foam roller group at 8 weeks when compared to the control group. No significant differences... Read More »
Level 1 RCT
6%
Synopsis: Sixty-one patients with knee osteoarthritis were randomized to receive an open-label placebo with verbal suggestions indicating pain relief (n=21) or mood improvement (n=21), or no treatment (n=19).The primary outcomes of interest included knee pain and function (Numeric Rating Scale [NRS]; Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC]).Secondary outcomes of interest included course of pain and mood ratings, need for analgesics, global clinical improvement, quality of life, perceived stress, salivary cortisol, and heart rate variation.Outcomes were assessed after 21 days of intervention.Results revealed patients who received an open-label placebo had significantly lower NRS and WOMAC pain scores, as well as a greater perceived clinical improvement vs. Read More »
Author verified Level 1 RCT
5%
Synopsis: Fifty female recreational runners with medial tibial stress syndrome (shin splints) were randomized to receive an 18-week multimodal intervention program (icing, ankle stretching and strengthening, extracorporeal shockwave therapy) plus the use of arch support foot orthoses (n=25) or a sham orthoses (n=25).Outcomes of interest included pain intensity, condition severity, perceived treatment effect, and the Short-Form 36 (SF-36) quality of life questionnaire.Results revealed significantly greater improvement in pain intensity, condition severity, perceived treatment effect, and SF-36 physical function and bodily harm sub-scores in the foot orthoses group vs. Read More »
Level 1 RCT
3%
Synopsis: One hundred and twenty patients with lumbar facet joint syndrome due to osteoarthritis were randomized to receive an ultrasound-guided intra-articular injection of methylene blue (n=60) or diprospan (n=60).The primary outcome of interest was pain on a Numeric Rating Scale (NRS), measured up to 6 months post-operation.Secondary outcomes of interest included lumbar function, sleep quality, depression severity, treatment efficacy, post-operative analgesic consumption, and the incidence of complications.Results revealed significantly lower pain scores, better lumbar function and sleep quality, lower depression severity, and a lower incidence of hyperglycemia with methylene blue injection vs. Read More »
Level 1 RCT
3%
Synopsis: Sixty patients with myofascial pain syndrome were randomized to receive repeated trapezius muscle injections (TMI, n=30) or a TMI followed by an erector spinae plane block (ESPB).The primary outcome of interest was pain measured with a visual analogue scale.In both groups, the VAS scores decreased significantly from baseline. The combined TMI... Read More »
Level 1 RCT
3%
Synopsis: One hundred and thirty patients with plantar fasciitis were randomized to receive ultrasound-guided interventional therapy with the use of artificial intelligence (AI) for image processing (n=65) or without AI.The outcomes of interest included pain on a Visual Analog Scale (VAS), plantar fascia thickness, elasticity, and blood flow index, AOFAS ankle function scores, and nursing satisfaction. Results revealed all... Read More »
Level 1 RCT
3%
Synopsis: One hundred and seven patients with medial compartment osteoarthritis were randomized to receive unicompartmental knee arthroplasty (UKA; n=57) or total knee arthroplasty (TKA; n=50).The primary outcomes of this trial were to assess patient-reported outcomes such as Knee Injury and Osteoarthritis Outcome Score, Joint Replacement (KOOS, JR), Knee Society Score (KSS), Forgotten Joint Score (FJS), range of motion (ROM), and VR-12 global health scores at 6 weeks and 6 months follow-up.Radiographic and surgical complications were also recorded.The results of this trial showed no significant differences in KOOS, JR, KSS, and FJS at 6 weeks and 6 months follow-up. Significant differences were... Read More »
Level 1 RCT
3%
Synopsis: Ninety-nine patients with at least 1 previous hip arthroplasty dislocation were randomized to receive standard care plus 12 weeks of hip bandaging to reduce hip range of motion (n=50) or standard care alone (n=49).The primary outcome of interest was the rate of redislocation after treatment.Secondary outcomes of interest included the Oxford Hip Score, Short Form 36 (SF-36) physical and mental component scores, and patient satisfaction.Intention-to-treat analysis results revealed no significant differences between the two groups in all outcomes. However, in the... Read More »
Level 1 RCT
3%
Synopsis: Two hundred patients with symptomatic osteoarthritis of the knee were randomized to receive either Thai medicinal plant-4 (TMP-4) cream (n=100) or diclofenac gel (n=99).Outcomes that were assessed in this trial were Visual Analog Scale (VAS) scores for knee pain and stiffness, 10-step stair climb test, timed up and go, and Knee Injury and Osteoarthritis Outcome Score (KOOS) at 2 and 4 weeks. The results of... Read More »
Level 1 RCT
2%
Synopsis: Eighty-five patients with symptomatic knee osteoarthritis (OA) were randomized to receive 2 injections consisting of a single intra-articular injection of hyaluronic acid (HA) followed by platelet-rich plasma (PRP; n=43) or the single injection group consisting of PRP alone (n=42).The primary outcome of interest was pain evaluated using the Visual Analogue Scale (VAS) at 1,3, and 6-months follow-up.Secondary outcomes of interest included the following: the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and its associated subscales (pain, stiffness, and function), Lequesne index, single leg stance test (SLS), patient satisfaction, and usage of acetaminophen which all secondary outcomes were evaluated at 1, 3, and 6-months follow-up.Results of this study demonstrated that VAS was statistically significantly improved at 6-months follow-up in the combined injection group vs PRP alone (p=0.020).For secondary outcomes, WOMAC function and total scores, Lequesne Index, SLS, and patient satisfaction scores were not statistically significantly different between 2 groups at all timepoints (p>0.05).However, WOMAC pain and stiffness were both statistically significantly higher in the combined injection group vs PRP alone at 1-month follow-up (p=0.025, p=0.011; respectively). Furthermore, the consumption... Read More »
Level 1 RCT