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You are viewing the most viewed ACE Reports by Sports Medicine Specialists over the last 30 days in all specialties.
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①
Synopsis:
Sixty athletes with MRI-confirmed grade 2 hamstring injuries were randomized to receive ultrasound-guided Platelet-Rich Plasma (PRP) injections plus standard therapy (n=30) or standard therapy alone (n=30).The primary outcome of interest was time to return to play.Secondary outcomes included MRI healing at 21 days, re-injury rates, and adverse events, with follow-up extending to 24 months.Overall, the results of the study revealed that PRP significantly accelerated return to play, improved MRI healing at 21 days, and trended toward lower re-injury rates.No adverse events occurred. These findings suggest...
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Level 1 RCT
9%
①
Synopsis:
One hundred thirty-two patients with Kellgren-Lawrence grade 1-3 knee osteoarthritis were randomized to receive three weekly intra-articular injections of either LR-PRP (n=66) or LP-PRP (n=66).The primary outcome was the change in the International Knee Documentation Committee (IKDC) subjective score at 12 months.Secondary outcomes included pain, function, and quality of life assessed through various scales (KOOS, WOMAC, VAS, EQ-5D, Tegner activity scale), as well as objective measures such as range of motion and quadriceps circumference.Outcomes were evaluated at baseline and at 2, 6, and 12 months.Overall, both groups showed significant improvement in subjective and objective outcomes, with no significant differences except for a transient greater improvement in IKDC at 2 months in the LR-PRP group, and minor differences in ROM and quadriceps circumference at specific time points.No severe adverse events were reported, and the rate of treatment failure was similar. The study concluded...
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Level 1 RCT
8%
②
Synopsis:
Nine studies (6 randomized controlled trials and 3 prospective comparative studies) were selected to examine the effects of leukocyte-poor platelet rich plasma and leukocyte-rich platelet rich plasma in knee osteoarthritis treatment.Due to the presence of only one direct comparison between LP-PRP and LR-PRP at the time of the study, studies which compared either to hyaluronic or placebo were included, and network meta-analysis was undertaken.Primary outcome was the incidence of local adverse events, while secondary efficacy outcomes included the change in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores and International Knee Documentation Committee (IKDC) scores.Incidence of local adverse events was higher with LP-PRP or LR-PRP compared to HA or placebo, and both were ranked at approximately 20% of being the best treatment for the outcome.Nevertheless, the difference between LP-PRP and LR-PRP for incidence of local adverse events was not significant. LP-PRP was ranked...
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Author verified Level 2 Meta Analysis
8%
①
Synopsis:
Ninety patients with intra-articular hip disorders, mainly osteoarthritis, were randomized to receive fluoroscopy-guided intra-articular steroid injection via the anterior approach (n=30), the anterolateral approach (n=30), or the proximal anterolateral approach (n=30).The primary outcome was successful injection in a single attempt.Secondary outcomes included pain during injection (VAS), radiation exposure, complications, and short-term functional improvement measured by the modified Harris hip score (mHHS).Outcomes were assessed at baseline and 2 weeks post-injection.Overall, the results revealed no significant differences between approaches in single-attempt success, VAS pain, radiation exposure, or mHHS improvement. The study concludes...
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Level 1 RCT
6%
②
Synopsis:
1184 Computer workers from 7 Dutch organizations partook a health questionnaire were randomized to two groups, one receiving the feedback on their scores and a preventive advice and the other group continuing with the usual care. The effectiveness of the RSI QuickScan intervention program was found to be small and limited to a decrease in some risk factors exposures only, with no difference in the prevalence of symptoms or sick leave between the groups.
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Author verified Level 2 RCT
4%
Synopsis:
Seventy patients with rotator cuff tears were randomized to receive either hyaluronic acid injection (n=35) or placebo (n=35) after arthroscopic rotator cuff repair.The primary outcome of interest was tendon integrity assessed by MRI using the Sugaya classification.Secondary outcomes included VAS pain scores, ASES, CONSTANT scores, range of motion, and strength.Outcomes were assessed at 2 weeks, 3 months, 6 months, and 12 months.Overall, the results of the study revealed that hyaluronic acid did not improve pain or functional scores compared with placebo but was associated with greater recovery of abduction, internal rotation, and external rotation at 6 and 12 months, and a lower re-tear rate on MRI (14.4% vs 26.7%). The findings suggest...
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Conference Report
3%
Synopsis:
Ninety patients with large (3–5 cm) and massive (>5 cm) rotator cuff tears were randomized to undergo arthroscopic repair with SLRS (n=26), KD (n=26), or KL (n=24).The primary outcome was retear rate at one year, assessed by 3T MRI.Secondary outcomes included range of motion (ROM), ASES, Constant, UCLA, and VAS scores, measured up to a mean of 20–21 months.Overall, all three groups experienced significant postoperative improvement in functional scores and ROM, with no significant differences between groups.However, retear rates were significantly higher with SLRS (38%) compared with KD (9.5%) and KL (11.7%) (p=0.04). These findings suggest...
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Conference Report
3%
①
Synopsis:
One hundred fifty-two patients with non-specific chronic low back pain (CLBP) were randomized to receive individualized cognitive functional therapy (CFT)(n=76) or a sham intervention (neutral talking plus detuned low-level laser; n=76).The primary outcomes were pain intensity (0–10) and Oswestry Disability Index (0–100) at 6 weeks.Secondary outcomes included pain and disability at 3 and 6 months, functioning, pain self-efficacy, global perceived effect, and analgesic use.Outcomes were assessed pre-treatment, post-treatment (6 weeks), and at 3 and 6 months.Overall, the results revealed clinically meaningful, statistically significant advantages for CFT over sham at 6 weeks that persisted through 6 months. In short, CFT...
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Level 1 RCT
2%
②
Synopsis:
109 patients with degenerative knee cartilage were randomized to determine the efficacy of platelet-rich plasma (PRP) compared to viscosupplementation via hyaluronic acid (HA) as a treatment method.Patients were allocated to three injections of either solution, and were followed up for 12 months.Results revealed that there were no differences between groups in clinical outcome for the duration of the study. Interestingly, a sub-group...
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Level 2 RCT
2%
Five-Year Stability of Cementless 3D-Printed vs Cemented Tibial Components - Total Knee Arthroplasty
①
Synopsis:
Seventy-two patients with knee osteoarthritis were randomized to receive a cementless 3D-printed cruciate-retaining tibial component (n=36) or a cemented cruciate-retaining tibial component (n=36).The primary outcome was maximum total point motion (MTPM) of the tibial component at 5 years.Secondary outcomes included progression of migration between 2 and 5 years, the proportion of continuously migrating implants, and patient-reported outcomes (KSS, KOOS, FJS).Follow-up assessments were performed at baseline, 3 months, 1, 2, and 5 years.Overall, the results revealed no significant difference in mean MTPM between cementless and cemented groups at 5 years.Progression of migration occurred in the cemented group beyond 2 years, whereas the cementless implants stabilized after early migration.Clinical outcomes were comparable between groups. These findings suggest...
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Level 1 RCT