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Synopsis: Two hundred and seven studies with 32959 participants were analyzed in this network meta-analysis.The aim of this study was to compare outpatient treatments for managing acute pain from non-low back musculoskeletal injuries.Results revealed that the treatment with the greatest benefit was using topical nonsteroidal anti-inflammatory agents (NSAIDs).Afterwards, oral NSAIDs were beneficial which was followed by acetiminophen with or without diclofenac.The benefits included relieving pain 1-7 days, as well physical functioning , and symptom relief. Moreover, topical NSAIDs demonstrated increase in treatment satisfaction. Fentanyl and acetaminophen... Read More »
Meta Analysis
8%
Synopsis: Patients were randomized to investigate the most suitable treatment for lateral epicondylitis; patients received physiotherapy, Extracorpeal Shockwave Therapy (ESWT), prolotherapy, or Platelet-Rich-Plasma (PRP) treatment. The results of the treatments at the mean 22 month follow-up indicated that prolotherapy and PRP produced better clinical outcomes than the other two groups, where PRP displayed significantly better DASH scores than the prolotherapy treatment. Read More »
Conference Report
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Synopsis: Findings of two randomized controlled trials were pooled in order to investigate if method of corticosteroid injection - either image-guided or anatomical landmark guided (blind) - impacted clinical outcome in patients suffering from shoulder pain.Clinical outcomes of pain and function were reported at 6 weeks, and the incidences of adverse events were recorded.Pooled effects illustrated that pain and function at 6 weeks were significantly improved with image-guided injections compared to blind injections. Incidence of adverse... Read More »
Level 1 Meta Analysis
8%
Synopsis: 54 patients with chronic midportion Achilles tendinopathy undergoing an eccentric exercise programme were randomized to receive either a platelet-rich plasma (PRP) injection or a saline injection (placebo), in order to determine whether PRP injections would result in enhanced tendon structure and neovascularisation that could be observed through ultrasonographic methods. Following evaluations over a 24 week period, the results indicated that no significant differences existed in neovascularisation scores between groups and that PRP injections did not contribute to improved tendon structure. Read More »
Author verified Level 1 RCT
8%
Synopsis: Data from 8 articles (9 studies; 3 RCTs) was included in this systematic review to ascertain the effectiveness of platelet-rich plasma (PRP) for the treatment of lateral epicondylitis.The systematic review demonstrated that the combined effect size resulted in significant improvements in pain and function with PRP: of the 9 included studies (5 RCTs), 2 cohort studies indicated that PRP improved clinical satisfaction scores,1 case-control study suggested that PRP induced a significantly superior improvement in symptoms compared with bupivacaine. Two smaller trials... Read More »
Level 2 Meta Analysis
8%
Synopsis: Data from 6 randomized controlled trials (RCTs) was systematically reviewed to investigate the efficacy of platelet-rich plasma (PRP) for the management of chronic lateral epicondylar tendinopathy, compared to placebo or other treatments.The search identified six randomized controlled trials of variable methodological quality (PEDro). The evidence presented... Read More »
Author verified Level 2 Meta Analysis
8%
Synopsis: 54 patients undergoing anatomic triple-bundle anterior cruciate ligament reconstruction (ACLR) were randomized to receive either the TightRope (Arthrex) fixation device or the EndoButton-CL (Smith & Nephew) fixation device.The purpose of this study was to determine the difference between groups in the frequency of failing to fix the device on the femoral cortex on either the first attempt, or an additional two more trials at turning the button. Results demonstrated a... Read More »
Conference Report
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Synopsis: 8 randomized controlled trials (1100 patients/fractures) comparing bipolar and unipolar hemiarthroplasty in elderly patients with femoral neck fractures were included in this study.The purpose of this meta-analysis was to compare the two surgical treatments in terms of clinical and functional outcomes. The results displayed... Read More »
Level 1 Meta Analysis
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Synopsis: Five randomized controlled trials were included in this meta-analysis which sought to investigate the efficacy of mesenchymal stem cell injections in patients with knee osteoarthritis.Included studies featured various control groups, including placebo injection, hyaluronic acid injection, and no injection, as well as various concomitant treatments, including high tibial osteotomy, microfracture, platelet rich plasma injection and hyaluronic acid injection.Accordingly, clinical heterogeneity was assumed.Data was pooled from 12-24 month time points. Analyses on visual... Read More »
Level 2 Meta Analysis
8%
Synopsis: 32 patients were included in this study comparing ultrasound-guided corticosteroid injection to ozone injection for the treatment of shoulder impingement syndrome.The primary outcomes of interest were pain on a Visual Analog Scale (VAS), the Constant score, and the Shoulder Pain and Disability Index (SPADI) score.Secondary outcomes of interest included range of motion, subacromial bursa thickness, supraspinatus tendon thickness and acromiohumeral thickness.Follow up was performed at 2 weeks and 2 months post-injection.Results revealed significantly greater improvement in all primary outcomes in the corticosteroid group compared to the ozone group. No significant differences... Read More »
Level 2 RCT
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