To unlock this feature and to subscribe to our weekly evidence emails, please create a FREE orthoEvidence account.

SIGNUP

Already Have an Account?

Loading...
Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
To focus on specific sub specialties check/uncheck boxes on left
29%
24%
10%
8%
5%
5%
5%
5%
4%
3%
2%
1%
Displaying
100%
8%
Synopsis: One hundred patients with chronic midportion Achilles tendinopathy were randomized to receive either exercise therapy combined with ultrasonography-guided corticosteroid injection (n=48) or exercise therapy with placebo injection (n=52).The primary outcome was improvement in the Victorian Institute of Sport Assessment–Achilles (VISA-A) score at 6 months.Secondary outcomes included tendon thickness, pain during activity and in the morning (measured by VAS), and global assessment of treatment response.Outcomes were assessed at baseline and 1, 2, 3, 6, 12, and 24 months.Overall, the results revealed that the corticosteroid group showed a significantly greater improvement in VISA-A scores at 6 months, accompanied by improved tendon morphology and early symptom relief, with no increase in adverse events. These findings suggest... Read More »
Level 1 RCT
6%
Synopsis: One hundred and nineteen patients with insertional Achilles tendinopathy were randomized to received extracorporeal shockwave therapy with eccentric exercise (ESWT +EE) (n=58) or eccentric exercise (EE) and sham therapy (n=61).The primary outcome was function measured by the Victorian Institute of Sports Assessment-Achilles questionnaire (VISA-A).Secondary outcomes of interest included pain scores, the Foot and Ankle Outcome Score (FAOS), the Short Form Health Survey (SF-12), recurrence and failure of treatment.Both groups demonstrated significant improvements from baseline.No differences in the VISA-A, FAOS or SF-12 were found at any time point between groups. The EWST+EE group... Read More »
Level 1 RCT
5%
Synopsis: 192 patients with unilateral, symptomatic knee osteoarthritis were randomized to receive 3 weekly intra-articular injections of leukocyte-rich platelet-rich plasma (n=96) or leukocyte-poor platelet-rich plasma (n=96).The primary outcome of interest was the International Knee Documentation Committee (IKDC) score at 12 months.Secondary outcomes of interest included the Knee Injury and Osteoarthritis Outcomes Score (KOOS) sub-scales, the Tegner scale for activity/sporting level, and Euro-QoL Visual Analog Scale (EQ-VAS) for quality of life. No significant differences... Read More »
Level 1 RCT
5%
Synopsis: Three hundred twenty-one patients with degenerative meniscal tears were randomized to receive arthroscopic partial meniscectomy (n=159) or exercise-based physical therapy (n=162).The primary outcome of interest was patient-reported knee function assessed by the International Knee Documentation Committee (IKDC) questionnaire.Secondary outcomes included radiographic progression of knee osteoarthritis, symptomatic OA, pain during activities, physical functioning (KOOS-PS), and quality of life.Outcomes were assessed at multiple time points up to 5 years.Overall, the results of the study revealed that physical therapy was noninferior to surgery for knee function, with no clinically meaningful differences in OA progression or other secondary outcomes. These findings suggest... Read More »
Level 1 RCT
4%
Synopsis: One hundred five patients with clinically diagnosed knee osteoarthritis were randomized to receive a 6-week internet-based exercise and education program (n=48) or routine self-management care (n=57).The primary outcome of interest was change in self-reported knee pain using a numerical rating scale at 6 weeks.Secondary outcomes included physical function tests (30-second sit-to-stand, Timed Up-and-Go), WOMAC subscales (pain, stiffness, physical function), muscle strength, and quantitative sensory testing.Outcomes were assessed at baseline and 6 weeks.Overall, the results of the study revealed a significantly greater improvement in pain, function, and hamstring strength in the internet-based intervention group compared to usual care. These findings suggest... Read More »
Level 1 RCT
4%
Synopsis: Seventy-nine patients with greater trochanteric pain syndrome unresponsive to conservative treatment were randomized to receive a single ultrasound-guided injection of leukocyte-rich platelet-rich plasma (n=39) or saline placebo (n=40).The primary outcome of interest was the iHOT-12 score.Secondary outcomes included VAS for pain, EQ-5D index, EQ-5D VAS, and mHHS scores.Outcomes were assessed at 3, 6, and 12 months.Overall, the results of the study revealed no significant differences in any outcome measures between the PRP and placebo groups at any follow-up point. This suggests that... Read More »
Level 1 RCT
3%
Synopsis: One hundred patients with isolated traumatic meniscal tears were randomized to receive either arthroscopic partial meniscectomy (n=49) or standardized physical therapy (n=51), with the option for delayed arthroscopic partial meniscectomy after three months.The primary outcome was the IKDC score at 24 months, which assesses knee symptoms, function, and ability to participate in sports.Secondary outcomes included KOOS, NRS pain, Lysholm, WOMET, Tegner activity level, and satisfaction with knee function.Follow-up assessments were conducted at multiple time points up to 24 months.Overall, both groups demonstrated clinically relevant improvements in IKDC scores, but there was no significant difference between the groups at 24 months. The study suggests... Read More »
Level 1 RCT
2%
Synopsis: One hundred twenty-eight patients with sciatica lasting 4 to 12 months due to lumbar disc herniation were randomized to receive either microdiscectomy (n=64) or 6 months of standardized nonoperative care (n=64).The primary outcome was leg pain intensity at 6 months.Secondary outcomes included back pain, Oswestry Disability Index (ODI), SF-36 quality-of-life scores, employment status, and treatment satisfaction, assessed at multiple time points up to 12 months.Overall, the results of the study revealed that microdiscectomy led to a significantly greater reduction in leg pain at 6 months and consistent improvements in secondary outcomes. These findings suggest... Read More »
Level 1 RCT
2%
Synopsis: Five randomized controlled trials (189 patients) comparing platelet-rich plasma (PRP) against conservative treatment for chronic Achilles tendinopathy were included in this systematic review and meta-analysis.Outcomes of interest included the Victorian Insitute of Sport Assessment (VISA-A) score, pain during activity on a Visual Analog Scale (VAS), and Achilles tendon thickness.VISA-A scores at 6 weeks favored the PRP group.Tendon thickness also favored the PRP group. All other outcomes... Read More »
Level 1 Meta Analysis
2%
Synopsis: 106 patients with adhesive capsulitis were randomized to one of three groups to determine which mode of conservative therapy - corticosteroid injections with distension, corticosteroid injections only, or treatment-as-usual (verbal education, use of other conservative therapy) - was associated with the greatest improvement in shoulder pain, function, and range of motion on the short-term (4 and 8 weeks) and long-term (12 months).Results demonstrated that patients in both corticosteroid injection intervention groups had significant improvements in pain, function, abduction, internal rotation, and external rotation when compared to the usual treatment group when assessed at 4 and 8 weeks. Long-term improvements in... Read More »
Level 2 RCT