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You are viewing the most viewed ACE Reports by Sports Medicine Specialists over the last 30 days in all specialties.
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Micro-fragmented Adipose Tissue Versus Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis
①
Synopsis:
One hundred and eighteen patients with symptomatic knee osteoarthritis were randomized to receive either intra-articular micro-fragmented adipose tissue injections (MF-AT; n=59) or platelet-rich plasma injections (PRP; n=59).The primary outcome of this trial was the change in International Knee Documentation Committee (IKDC) scores and pain subscale of the Knee Osteoarthritis Outcome Score (KOOS) from baseline to 6 months.Other outcomes such as KOOS subscales for functional improvement, EuroQol visual analog scale (EQ-VAS), EuroQol 5 Dimensions (EQ-5D), and Visual Analog Scale (VAS) for pain at 3, 6, 12, and 24 months.MRI findings using the Whole-Organ Magnetic Resonance Imaging (WORMS) score was also assessed.Statistically significant improvements in all clinical scores were apparent in the MF-AT group, except for EQ-VAS scores. IKDC and KOOS...
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Level 1 RCT
4%
①
Synopsis:
192 patients with unilateral, symptomatic knee osteoarthritis were randomized to receive 3 weekly intra-articular injections of leukocyte-rich platelet-rich plasma (n=96) or leukocyte-poor platelet-rich plasma (n=96).The primary outcome of interest was the International Knee Documentation Committee (IKDC) score at 12 months.Secondary outcomes of interest included the Knee Injury and Osteoarthritis Outcomes Score (KOOS) sub-scales, the Tegner scale for activity/sporting level, and Euro-QoL Visual Analog Scale (EQ-VAS) for quality of life. No significant differences...
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Level 1 RCT
4%
①
Synopsis:
Five randomized controlled trials (189 patients) comparing platelet-rich plasma (PRP) against conservative treatment for chronic Achilles tendinopathy were included in this systematic review and meta-analysis.Outcomes of interest included the Victorian Insitute of Sport Assessment (VISA-A) score, pain during activity on a Visual Analog Scale (VAS), and Achilles tendon thickness.VISA-A scores at 6 weeks favored the PRP group.Tendon thickness also favored the PRP group. All other outcomes...
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Level 1 Meta Analysis
3%
①
Synopsis:
492 patients with chronic, disabling low back pain were randomized to receive cognitive functional therapy (CFT) with the use of biofeedback sensors (n=163) or without biofeedback sensors (n=164), or usual care (n=165).The primary outcome of interest was pain-related physical activity limitation.Secondary outcomes of interest included pain outcomes, functional limitation, global improvement, patient satisfaction, adverse events, and cost-utility.Follow-up was conducted over a 52 week period.Both CFT groups significantly outperformed the usual care group in all outcomes, resulting in greater improvements in physical function, pain relief, improvement in outcomes, and fear avoidance, up to 52 weeks.Moreover, the CFT groups were significantly more cost-effective than the usual care group, resulting in a greater gain in quality adjusted life-years and a larger reduction in productivity loss.However, the use of CFT with biofeedback sensors did not result in any meaningful difference over CFT only.The results of this trial suggest that CFT could provide lasting, effective relief of chronic, disabling low back pain in a cost-effective manner vs.
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Level 1 RCT
3%
①
Synopsis:
This systematic review and meta-analysis included eight studies with 768 patients diagnosed with refractory frozen shoulder, comparing arthroscopic capsular release (ACR) versus manipulation under anesthesia (MUA).The pooled outcomes examined changes in pain (VAS), functional scores (ASES, CMS), range of motion, complication rates, and need for additional interventions.ACR provided statistically better pain relief after 12 months (p = 0.001) but did not meet the minimal clinically important difference. Rates of mild...
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Level 1 Meta Analysis
3%
②
Synopsis:
101 patients with an acute Achilles tendon rupture were randomized to one of two groups: a surgical group, wherein surgical repair was performed and early weight-bearing was encouraged, or a non-surgical group, wherein patients were treated conservatively and early weight-bearing was also encouraged.The purpose of this study was to evaluate these two treatment methods with respect to functional outcomes. Results indicated that...
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Level 2 RCT
3%
①
Synopsis:
141 patients undergoing total knee arthroplasty were randomized to receive either a cementless implant (n=76) or a cemented implant (n=65).Outcomes of interest included Oxford Knee Score (OKS), Knee Society Function Score, Forgotten Joint Score (FJS), percentage of normal knee, patient satisfaction, incidence of revision, and the incidence of reoperation.Outcomes were assessed at 2 and 6 years post-operation.There were no differences in all outcomes at 2 and 6 years except for patient satisfaction which was significantly better in the cementless group. The rate of...
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Level 1 RCT
2%
②
Synopsis:
22 young athletes with grade I or II unilateral inversion ankle sprain within 3 weeks of injury were randomized to plyometric training or resistive training for 6 week duration. At 6 week follow up, the plyometric rehabilitation following an acute ankle sprain resulted in significantly better functional performance than using resistive training alone.
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Author verified Level 2 RCT
2%
①
Synopsis:
One hundred twenty patients with anterior cruciate ligament (ACL) injuries were randomized to receive either postoperative intra-articular PRP injection (n=60) or no injection (control group; n=60) following ACL reconstruction.The primary outcome was the mean Knee Injury and Osteoarthritis Outcome Score (KOOS4) at 12 months postoperatively.Secondary outcomes included patient-reported outcomes, graft maturity (via MRI), and physical examinations conducted at 3, 6, and 12 months.Overall, the results indicated no statistically significant improvement in knee function or symptoms in the PRP group at 12 months. At 6 months,...
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Level 1 RCT
2%
Effect of Physical Exercise on Knee Muscle Function in Postmenopausal Women with Knee Osteoarthritis
①
Synopsis:
Five randomized controlled trials with 286 postmenopausal women with knee osteoarthritis were included in this systematic review and meta-analysis comparing physical exercise interventions, including aquatic and aerobic exercise, to control groups.Pooled outcomes included physical function, pain, stiffness, knee muscle function, and quality of life.The meta-analysis found significant improvements in physical function for the exercise group, with moderate effect sizes, though no significant differences were observed in pain or stiffness outcomes. Overall, the findings...
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Level 1 Meta Analysis