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Does Melatonin Improve Subjective Sleep Quality After Total Knee Arthroplasty?
November 2024
Does Melatonin Improve Subjective Sleep Quality After Total Knee Arthroplasty?
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The John N. Insall Award: Does Melatonin Improve Subjective Sleep Quality After Total Knee Arthroplasty? A Randomized, Placebo-Controlled Trial.
J Arthroplasty. 2024 01-Aug;():. 10.1016/j.arth.2024.01.018Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred seventy-two patients undergoing total knee arthroplasty for osteoarthritis were randomized to receive either 5 mg melatonin (n=86) or 125 mg vitamin C placebo (n=86). The primary outcome was the Pittsburgh Sleep Quality Index (PSQI). Secondary outcomes included patient-reported measures of pain and physical function, opioid prescriptions, medication compliance, and adverse events. Outc...
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