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Synopsis:
Fifty-seven patients with displaced type II distal clavicle fractures were randomized to receive either operative treatment (n=27) or non-operative treatment (n=30).The primary outcome of interest was the Disabilities of the Arm, Shoulder, and Hand (DASH) score at two years.Secondary outcomes included union rates, re-operation rates, satisfaction with shoulder appearance, and return to activities.Outcomes were assessed at one and two years.Overall, the results revealed no significant difference in DASH scores between the two groups at two years, indicating excellent function in both groups.However, 48% of the operative group required hardware removal, while 20% of the non-operative group required surgical intervention due to non-union.Union rates were comparable at two years. These findings suggest...
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Conference Report
①
Synopsis:
Three hundred seventy-seven adults with knee osteoarthritis were randomized to receive high-intensity strength training (n=127), low-intensity strength training (n=126), or attention control (n=124).The primary outcomes were knee pain measured by the WOMAC scale and knee joint compressive force during walking.Secondary outcomes included physical function, 6-minute walk distance, joint space width, thigh muscle and fat volume, inflammatory markers, and muscle strength.Outcomes were assessed at 6 and 18 months.Overall, the results of the study revealed no statistically significant differences in primary outcomes between high-intensity training and either low-intensity or control groups. The findings suggest...
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Level 1 RCT
Synopsis:
Nine randomized controlled trials (RCTs) including 1,104 patients undergoing fracture fixation were analyzed in this meta-analysis comparing NSAIDs to a control group for pain management.The primary outcome was radiographic nonunion.The pooled results showed that 8.9% of patients receiving NSAIDs experienced nonunion, compared to 3.9% in the control group.A subgroup analysis indicated that short-term NSAID use (<2 weeks) was still associated with an increased risk of nonunion.No cases of nonunion were observed in pediatric patients (p > 0.99). These findings suggest...
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Conference Report
①
Synopsis:
This systematic review and meta-analysis included 32 studies with a total of 1,753 patients undergoing total hip arthroplasty, comparing land-based preoperative and postoperative exercise interventions to usual care or minimal intervention.Pooled outcomes of interest included self-reported physical function, pain intensity, quality of life, gait speed, lower body muscle strength, lower body flexibility, anxiety, hospital length of stay, and adverse events.The results showed that neither preoperative nor postoperative exercise interventions significantly improved self-reported physical function, with low to moderate certainty.There was no meaningful association with hospital length of stay or postoperative hip muscle strength. The findings suggest...
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Level 1 Meta Analysis
Synopsis:
Seventy patients with isolated, closed humeral shaft fractures were randomized to receive either open reduction and plate fixation (n=36) or functional bracing (n=34).The primary outcome of interest was the DASH score at three months.Secondary outcomes included health-related quality of life (HRQoL), pain scores, shoulder/elbow range of motion, complications, and return to activity over one year.Overall, the results revealed that surgery led to superior functional outcomes at three months (mean DASH 24.5 vs.39.4; MD 15.0, p=0.006) and improved HRQoL and pain scores over the first six months.Surgery also resulted in better shoulder and elbow mobility and a higher rate of return to sport.However, by one year, there were no significant differences between groups. These findings suggest...
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Conference Report
①
Synopsis:
One hundred twenty-four patients with postoperative stiffness after primary TKA due to osteoarthritis were randomized to receive either MUA with PT alone (n=58) or MUA with PT plus one dose of pre-MUA intravenous dexamethasone (8 mg) and 14 days of oral celecoxib (200 mg) (n=66).The primary outcome of interest was knee ROM at 6 weeks after MUA.Secondary outcomes included knee ROM at 1 year and clinical outcome measures at both time points.Outcomes were assessed immediately after MUA, at 6 weeks, and at 1 year.Overall, the results revealed that while MUA significantly improved ROM immediately by 46°, there was no statistically significant difference between the treatment and control groups at 6 weeks or at 1 year.Clinical outcomes were also similar between groups. These findings suggest...
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Level 1 RCT
①
Synopsis:
One hundred sixty-four patients with moderate to severe symptomatic medial knee osteoarthritis were randomized to receive flat flexible shoes (n=82) or stable supportive shoes (n=82) for at least six hours daily over six months.The primary outcomes were changes in walking pain (measured on an 11-point numerical rating scale) and physical function (assessed by the Western Ontario and McMaster Universities Osteoarthritis Index).Secondary outcomes included additional pain measures, physical activity, and quality of life.At six months, 161 participants (98%) completed primary outcome assessments.The results showed that stable supportive shoes led to significantly greater reductions in walking pain than flat flexible shoes (mean difference, 1.1 units; 95% CI, 0.5 to 1.8; P=0.001), but there was no significant difference in function improvement between groups (mean difference, 2.3 units; 95% CI, −0.9 to 5.5; P=0.167).Quality of life and ipsilateral hip pain also favored stable supportive shoes.More adverse events were reported with flat flexible shoes. These findings suggest...
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Level 1 RCT
①
Synopsis:
Six studies involving 517 patients with neck pain were included in this systematic review and meta-analysis, comparing cervical manipulations to thoracic or cervicothoracic manipulations.Pooled outcomes of interest included pain intensity, neck disability, and cervical range of motion.The analysis revealed no significant differences in pain reduction, disability improvement, or cervical range of motion between the intervention groups. Moderate to very...
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Level 1 Meta Analysis
①
Synopsis:
Six hundred sixty-nine patients with acute ankle fractures were randomized to receive either a plaster cast (n=334) or a fixed-angle removable brace (n=335) following operative or nonoperative initial management.The primary outcome of interest was ankle function, measured using the Olerud-Molander Ankle Score (OMAS).Secondary outcomes included quality of life (EuroQol five-dimension five-level questionnaire), disability (Disability Rating Index), and complications.Outcomes were assessed at 16 weeks, 24 weeks, and two years.Overall, the study found no significant differences in ankle function between the two groups at two years.Quality of life and disability outcomes were also similar. These findings suggest...
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Level 1 RCT
①
Synopsis:
Five randomized controlled trials (189 patients) comparing platelet-rich plasma (PRP) against conservative treatment for chronic Achilles tendinopathy were included in this systematic review and meta-analysis.Outcomes of interest included the Victorian Insitute of Sport Assessment (VISA-A) score, pain during activity on a Visual Analog Scale (VAS), and Achilles tendon thickness.VISA-A scores at 6 weeks favored the PRP group.Tendon thickness also favored the PRP group. All other outcomes...
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Level 1 Meta Analysis