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You are viewing the most viewed ACE Reports by Physiotherapists over the last 30 days in all specialties.
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Micro-fragmented Adipose Tissue Versus Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis
①
Synopsis:
One hundred and eighteen patients with symptomatic knee osteoarthritis were randomized to receive either intra-articular micro-fragmented adipose tissue injections (MF-AT; n=59) or platelet-rich plasma injections (PRP; n=59).The primary outcome of this trial was the change in International Knee Documentation Committee (IKDC) scores and pain subscale of the Knee Osteoarthritis Outcome Score (KOOS) from baseline to 6 months.Other outcomes such as KOOS subscales for functional improvement, EuroQol visual analog scale (EQ-VAS), EuroQol 5 Dimensions (EQ-5D), and Visual Analog Scale (VAS) for pain at 3, 6, 12, and 24 months.MRI findings using the Whole-Organ Magnetic Resonance Imaging (WORMS) score was also assessed.Statistically significant improvements in all clinical scores were apparent in the MF-AT group, except for EQ-VAS scores. IKDC and KOOS...
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Level 1 RCT
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Effect of Physical Exercise on Knee Muscle Function in Postmenopausal Women with Knee Osteoarthritis
①
Synopsis:
Five randomized controlled trials with 286 postmenopausal women with knee osteoarthritis were included in this systematic review and meta-analysis comparing physical exercise interventions, including aquatic and aerobic exercise, to control groups.Pooled outcomes included physical function, pain, stiffness, knee muscle function, and quality of life.The meta-analysis found significant improvements in physical function for the exercise group, with moderate effect sizes, though no significant differences were observed in pain or stiffness outcomes. Overall, the findings...
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Level 1 Meta Analysis
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①
Synopsis:
Five randomized controlled trials (189 patients) comparing platelet-rich plasma (PRP) against conservative treatment for chronic Achilles tendinopathy were included in this systematic review and meta-analysis.Outcomes of interest included the Victorian Insitute of Sport Assessment (VISA-A) score, pain during activity on a Visual Analog Scale (VAS), and Achilles tendon thickness.VISA-A scores at 6 weeks favored the PRP group.Tendon thickness also favored the PRP group. All other outcomes...
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Level 1 Meta Analysis
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①
Synopsis:
492 patients with chronic, disabling low back pain were randomized to receive cognitive functional therapy (CFT) with the use of biofeedback sensors (n=163) or without biofeedback sensors (n=164), or usual care (n=165).The primary outcome of interest was pain-related physical activity limitation.Secondary outcomes of interest included pain outcomes, functional limitation, global improvement, patient satisfaction, adverse events, and cost-utility.Follow-up was conducted over a 52 week period.Both CFT groups significantly outperformed the usual care group in all outcomes, resulting in greater improvements in physical function, pain relief, improvement in outcomes, and fear avoidance, up to 52 weeks.Moreover, the CFT groups were significantly more cost-effective than the usual care group, resulting in a greater gain in quality adjusted life-years and a larger reduction in productivity loss.However, the use of CFT with biofeedback sensors did not result in any meaningful difference over CFT only.The results of this trial suggest that CFT could provide lasting, effective relief of chronic, disabling low back pain in a cost-effective manner vs.
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Level 1 RCT
3%
②
Synopsis:
101 patients with an acute grade 1 or 2 ankle sprain were randomized to be managed with an early therapeutic exercise program or a conventional PRICE (protection, rest, ice, compression and elevation) protocol.It was observed that after early incorporating therapeutic exercises during the first week after an ankle sprain brings about significant improvements in physical activity and improved functional status compared to the standard treatment at weeks 1 and 2. At 16-week follow-up,...
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Author verified Level 2 RCT
3%
①
Synopsis:
This systematic review and meta-analysis included 14 randomized controlled trials involving patients with patellofemoral pain syndrome (PFPS).The study compared Kinesio taping (KT) to various control treatments, including placebo taping, exercise therapy, and other physiotherapies.Pooled outcomes of interest included short-, medium-, and long-term pain relief, knee function (Kujala score), and knee symptoms (Lysholm score).The meta-analysis revealed significant short-term pain relief in the KT group, moderate mid-term relief, and modest long-term pain relief compared to control.However, no significant improvements were noted in knee function or symptoms. The findings suggest...
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Level 1 Meta Analysis
3%
①
Synopsis:
Forty patients undergoing total knee arthroplasty were randomized to receive either intensive elastic resistance training (n=20) or a conventional physiotherapy protocol (n=20).The primary outcome of interest was self-administered physical function, assessed through the WOMAC questionnaire.Secondary outcome measures included pain intensity, kinesiophobia, catastrophizing, self-efficacy, range of motion, inflammatory markers (procalcitonin and C-reactive protein), and timed up-and-go (TUG) test.Outcomes were assessed at 24, 48, and 72 hours after surgery.Overall, the results of the study revealed that the intervention group showed significant improvements in physical function, pain intensity, and psychosocial variables compared to the control group. These findings suggest...
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Level 1 RCT
2%
①
Synopsis:
36 patients with cervical radiculopathy (CR) were randomized to either receive manual therapy and exercise with a focus on increasing the size of the intervertebral foramen (IVF) of the affected nerve root, or a similar treatment without this specific aim.The purpose of the study was to compare these two interventions.The primary outcome, Neck Disability Index, as well as the secondary outcomes of QuickDASH and a numeric rating scale score, indicated no significant difference between the two groups when assessed at 4 and 8 weeks. Both groups demonstrated...
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Author verified Level 1 RCT
2%
①
Synopsis:
Forty-seven patients with single-level cervical radiculopathy were randomized to receive either BRYAN CDA (cervical disk arthroplasty; n=22) or ACDF (anterior cervical discectomy and fusion; n=25) in a prospective, randomized, controlled trial conducted as a Food and Drug Administration Investigational Device Exemption trial.The primary outcomes of interest included visual analog scales (VAS) for neck and arm pain, neck disability index (NDI), and reoperation rates.The follow-up rate was 91.3%.Both groups demonstrated significantly improved NDI, VAS arm pain, and VAS neck pain scores at 20 years compared to preoperative scores.However, there were no significant differences between CDA and ACDF groups at 20 years for NDI, VAS arm pain, and VAS neck pain scores.Reoperations were reported in 41.7% of ACDF patients and 10.0% of CDA patients. Both CDA and...
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Level 1 RCT
2%
①
Synopsis:
Seven studies including 534 patients who underwent total knee arthroplasty were analyzed in this systematic review and meta-analysis, comparing kinesiotape plus standard rehabilitation versus standard rehabilitation alone.Pooled outcomes of interest included pain, knee flexion range of motion, edema, and mobility.Kinesiotape combined with standard rehabilitation showed significant but modest reductions in pain and improvements in range of motion at both early (2-4 days) and late (6-8 days) post-operative time points. However, edema and...
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Level 1 Meta Analysis