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You are viewing the most viewed ACE Reports by Physiotherapists over the last 30 days in all specialties.
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①
Synopsis:
192 patients with unilateral, symptomatic knee osteoarthritis were randomized to receive 3 weekly intra-articular injections of leukocyte-rich platelet-rich plasma (n=96) or leukocyte-poor platelet-rich plasma (n=96).The primary outcome of interest was the International Knee Documentation Committee (IKDC) score at 12 months.Secondary outcomes of interest included the Knee Injury and Osteoarthritis Outcomes Score (KOOS) sub-scales, the Tegner scale for activity/sporting level, and Euro-QoL Visual Analog Scale (EQ-VAS) for quality of life. No significant differences...
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Level 1 RCT
6%
①
Synopsis:
Sixty patients with knee osteoarthritis were randomized to receive intra-articular prolotherapy (IG, n=20), peri-articular perineural injection (PG, n=20), or a combination of the two treatments (I + PG, n=20).The primary outcome of interest was pain intensity measured using the Visual Analogue Scale (VAS).Secondary outcomes included knee function measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and pressure pain threshold (PPT).Outcomes were assessed at baseline, 2, 4, and 8 weeks.Overall, the results revealed that the I + PG group showed significantly greater improvements in pain and function compared to the single therapy groups, with a significant decrease in VAS and WOMAC scores at 4 and 8 weeks. This suggests that...
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Level 1 RCT
6%
①
Synopsis:
Twenty-seven randomized controlled trials that compared the safety and efficacy of platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC), and hyaluronic acid (HA) were included in this meta-analysis.Outcomes of interest included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), pain on a Visual Analog Scale (VAS), International Knee Documentation Committee (IKDC), and Lequesne Index Score (LEQ).WOMAC, IKDC, and VAS scores favored PRP against HA.Similarly, in the network meta-analyses comparing BMAC and HA, WOMAC, IKDC, and VAS scores favored BMAC. No differences were...
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Author verified Level 1 Meta Analysis
6%
①
Synopsis:
Forty-five patients with patellofemoral pain syndrome were randomized to receive high-intensity laser therapy (HILT) and exercise (n=15), ultrasound and transcutaneous electrical nerve stimulation (US-TENS) and exercise (n=15), or ultrasound and interferential current (US-IFC) and exercise (n=15).The primary outcome of interest was the reduction in pain severity, measured by the visual analog scale (VAS).Secondary outcomes included knee flexion range of motion (FROM), Q angle, Kujala patellofemoral score, lower extremity functional scale (LEFS), and Timed Up and Go Test (TUG).Outcomes were assessed at baseline, after 2 weeks of treatment, and at 12 weeks post-treatment.Overall, the results of the study revealed that HILT was statistically more effective than the other two groups in reducing pain, improving knee flexion, and enhancing lower extremity functionality. This suggests that...
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Level 1 RCT
4%
①
Synopsis:
This systematic review and meta-analysis included 14 randomized controlled trials involving patients with patellofemoral pain syndrome (PFPS).The study compared Kinesio taping (KT) to various control treatments, including placebo taping, exercise therapy, and other physiotherapies.Pooled outcomes of interest included short-, medium-, and long-term pain relief, knee function (Kujala score), and knee symptoms (Lysholm score).The meta-analysis revealed significant short-term pain relief in the KT group, moderate mid-term relief, and modest long-term pain relief compared to control.However, no significant improvements were noted in knee function or symptoms. The findings suggest...
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Level 1 Meta Analysis
4%
①
Synopsis:
Forty-six patients with chronic ankle instability were randomized to receive strength training combined with acupuncture (n=24) or strength training alone (n=22).The primary outcome of interest was the improvement in balance ability.Secondary outcomes included changes in ankle motion perception, isokinetic muscle strength, and scores from the Cumberland Ankle Instability Tool (CAIT).Outcomes were assessed at baseline and after 8 weeks of intervention.Overall, the results of the study revealed that the experimental group, which received strength training and acupuncture, demonstrated greater improvements in balance and muscle strength compared to the control group. The findings suggest...
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Level 1 RCT
4%
①
Synopsis:
One hundred and forty-six patients 35–65 years of age with knee symptoms consistent with a degenerative medial meniscus tear were randomized into receiving arthroscopic partial meniscectomy (APM) or a sham surgery (diagnostic knee arthroscopy).Primary outcomes of interest included radiographic knee osteoarthritis through using the Kellgren and Lawrence knee osteoarthritis grading and the Osteoarthritis Research Society International (OARSI) instrument, as well as patient-related outcomes via the Western Ontario Meniscal Evaluation Tool (WOMET), the Lysholm knee score, and knee pain after exercise.Outcomes of interest were assessed 5 years post-operation.No significant differences between the APM and placebo groups were observed in all three patient-relevant outcomes, 5 years post-operation.A slight increase in the risk of radiographic knee osteoarthritis progression was observed in the APM group, however this was not significantly different.A significantly higher risk of mechanical symptoms was observed in the APM group. Otherwise, outcome comparisons...
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Author verified Level 1 RCT
4%
①
Synopsis:
Eighty-six patients with chronic symptomatic knee osteoarthritis were randomized to receive either high-dose cannabidiol (CBD; n=43) or placebo (n=43) as an add-on to continued paracetamol.The primary outcome of interest was the change in the Western Ontario and McMasters Universities Osteoarthritis Index (WOMAC) pain subscale over 8 weeks.Secondary outcomes included changes in WOMAC stiffness and physical function subscales, Visual Analogue Scale (VAS) pain scores, PainDETECT score, and SF-36 health survey scores.Outcomes were assessed at baseline, 4 weeks, 8 weeks, and follow-up at 12 weeks.Overall, the study revealed no significant difference in pain reduction between the CBD and placebo groups. The study concluded...
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Level 1 RCT
3%
①
Synopsis:
Three hundred thirty patients undergoing primary unilateral total knee arthroplasty for osteoarthritis were randomized to receive diosmin (n=167) or no diosmin (n=163).The diosmin group received 0.9 g twice daily for 14 days postoperatively, while the control group received no treatment or placebo.The primary outcome of interest was lower-extremity swelling measured at 24, 48, and 72 hours, and 14 days postoperatively.Secondary outcomes included pain during motion, pain at rest, Hospital for Special Surgery (HSS) scores, range of motion, levels of inflammatory biomarkers (C-reactive protein and interleukin-6), and the incidence of complications.Outcomes were assessed up to 14 days postoperatively.Overall, the results of the study revealed that diosmin significantly reduced lower-extremity swelling and pain during motion compared to the control group. The study suggests...
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Level 1 RCT
3%
①
Synopsis:
85 patients with isolated acute Rockwood type 3 acromioclavicular joint injury (ACJI) were randomized to receive either sling immobilization (n=42) or acromioclavicular joint stabilization (ACJS; n=43).Outcomes of interest included the Constant Shoulder Score, range of motion (ROM), American Shoulder and Elbow Surgeons (ASES) score, Taft score, Acromioclavicular Joint Instability (ACJI) score, pain on a Numeric Rating Scale (NRS), coracoclavicular (CC) distance, and the incidence of adverse events, measured up to 24 months.Constant scores were similar between the two groups at all time points.ROM, ACJI at 6 and 12 months, and CC distance at all time points were significantly better in the ACJS group compared to the sling immobilization group. NRS pain scores...
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Level 1 RCT