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You are viewing the most viewed ACE Reports by Primary Care Physicians over the last 30 days in all specialties.
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4%
②
Synopsis:
38 patients with sub-acute non-specific low back pain (NSLBP) were randomized to receive 7 weeks of either Core Stabilization Exercise (CSE) therapy or 7 weeks of standard therapy (ultrasound and thermal treatment).Outcomes measured included lumbar joint repositioning error, pain intensity, and functional disability.The results demonstrated that CSE therapy was associated with significantly less lumbar joint repositioning error compared to the control group after 7 weeks of intervention, and 4 weeks after the cessation of treatment. Moreover, pain intensity...
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Level 2 RCT
3%
①
Synopsis:
Seven randomized controlled trials were included in this meta-analysis evaluating the efficacy of corticosteroid injections in the treatment of enthesopathy of the extensor carpi radialis brevis origin.Included RCTs featured local anesthetic or placebo saline injections as a control.Results demonstrated significantly lower pain at 1 month with corticosteroid versus control injections, but no significant difference at 3 and 6 months. Functional scores and...
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Author verified Level 1 Meta Analysis
3%
Synopsis:
1583 patients with symptomatic knee osteoarthritis were randomized to either glucosamine monotherapy, chondroitin monotherapy, combined glucosamine and chondroitin therapy, celecoxib 200mg daily, or placebo.Patients were assessed over 24 weeks of treatment.In the primary analysis, only the celecoxib group demonstrated a significantly higher rate of patients attaining the primary efficacy endpoint - a reduction of WOMAC pain by a minimum of 20% relative to baseline - compared to placebo. However, when only...
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RCT
2%
①
Synopsis:
Three randomized controlled trials were included in this meta-analysis comparing pain and functional improvement between operative and nonoperative treatment for full-thickness rotator cuff tears.Follow-up was 12 months in each study. Results demonstrated that...
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Author verified Level 1 Meta Analysis
2%
②
Synopsis:
150 patients with an acute displaced midshaft clavicle fracture were randomized to treatment through either open reduction and internal fixation with a plate or nonoperative management with sling immobilization.Patients were followed-up at 6 weeks, 3 months, 6 months, and 12 months for outcome related to the Disabilities of the Arm, Shoulder, and Hand score, the Constant score, and the incidence of nonunion.Outcome on both the DASH score and the Constant score significantly favoured the plate group compared to the sling group at 6-week and 3-month follow-up, but no significant between-group differences were observed in the measures at 6 months or 12 months. The incidence of...
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Level 2 RCT
2%
②
Synopsis:
60 patients with bilateral secondary knee osteoarthritis to corticosteroid-induced osteonecrosis were randomized to have one knee treated with subchondral injection of mesenchymal stem cells, and one knee treated with total knee arthroplasty.Patients were assessed over a minimum of 8 years after treatment.Results demonstrated no significant difference between groups in outcome on the Knee Society Score at final follow-up. Rate of secondary...
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Level 2 RCT
2%
②
Synopsis:
18 patients with a displaced (>2mm) base of the 5th metatarsal fracture were randomized to be treated with either open reduction and internal fixation (ORIF) or nonoperative management with a short leg cast.The purpose of this study was to compare clinical measures of pain and function, time to union, and restoration of injured metatarsal length between groups.Follow-up was performed for an average of 8.5 weeks.Results demonstrated no significant differences in pain or functional scores, despite a significantly shorter time to union in the operative group.
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Level 2 RCT
2%
②
Synopsis:
34 patients with progressive multiple sclerosis were treated with titrated doses of Sativex (9-delta-tetrahydrocannabinol and cannabidiol oromucosal spray) or placebo in a randomly assigned order for 4 weeks each.The purpose of the study was to determine if of 9-delta-tetrahydrocannabinol and cannabidiol treatment significantly improves neurophysiological and clinical measures of spasticity, pain, function, fatigue and functional performance compared to placebo.There were no significant differences in improvements between treatments with regards to neurophysiological measures of spasticity, pain, function, fatigue and functional performance, but patients given 9-delta-tetrahydrocannabinol and cannabidiol had significantly improved modified Ashworth scale scores and a significantly larger percentage responded to treatment compared to placebo.Rates of side effects were similar between groups. Nine of the...
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Level 2 RCT
2%
Synopsis:
3424 patients scheduled for or who had undergone either total knee or hip arthroplasty with a 5-day course of rivaroxaban 10mg postoperatively were randomized to extended thromboprophylaxis with either aspirin 81mg daily or continued rivaroxaban 10mg daily.Patients were assessed for the incidence of venous thromboembolism and bleeding events over the first 90 days after surgery, Noninferiority analysis for efficacy demonstrated that extended aspirin was noninferior to extended rivaroxaban. Groups also demonstrated...
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Conference Report
1%
Simultaneous Achilles & plantar fascia stretching vs Achilles stretching alone for plantar fasciitis
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Synopsis:
50 patients with plantar fasciitis were randomized to a 4-week stretching protocol consisting of either simultaneous Achilles tendon and plantar fascia stretching or Achilles tendon stretching alone.Patients were assessed for outcomes related to pain, pressure pain threshold, ankle range of motion, and functional disability after 4 weeks. The results demonstrated...
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Level 2 RCT