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8%
Synopsis: 28 elderly patients with acute distal femur fractures or periprosthetic fractures of the hip or knee were randomized to receive either far cortical locking (FCL; n=16) or standard locking plate fixation (LPF; n=12).Outcomes of interest included the radiographic union scale (RUS) and time to union. RUS scores at... Read More »
Level 1 RCT
8%
Synopsis: Five randomized controlled trials (189 patients) comparing platelet-rich plasma (PRP) against conservative treatment for chronic Achilles tendinopathy were included in this systematic review and meta-analysis.Outcomes of interest included the Victorian Insitute of Sport Assessment (VISA-A) score, pain during activity on a Visual Analog Scale (VAS), and Achilles tendon thickness.VISA-A scores at 6 weeks favored the PRP group.Tendon thickness also favored the PRP group. All other outcomes... Read More »
Level 1 Meta Analysis
8%
Synopsis: Forty-seven patients with single-level cervical radiculopathy were randomized to receive either BRYAN CDA (cervical disk arthroplasty; n=22) or ACDF (anterior cervical discectomy and fusion; n=25) in a prospective, randomized, controlled trial conducted as a Food and Drug Administration Investigational Device Exemption trial.The primary outcomes of interest included visual analog scales (VAS) for neck and arm pain, neck disability index (NDI), and reoperation rates.The follow-up rate was 91.3%.Both groups demonstrated significantly improved NDI, VAS arm pain, and VAS neck pain scores at 20 years compared to preoperative scores.However, there were no significant differences between CDA and ACDF groups at 20 years for NDI, VAS arm pain, and VAS neck pain scores.Reoperations were reported in 41.7% of ACDF patients and 10.0% of CDA patients. Both CDA and... Read More »
Level 1 RCT
8%
Synopsis: This systematic review and meta-analysis included 14 randomized controlled trials involving 698 patients with low back pain.The studies compared the effects of respiratory exercises to routine lower back pain treatments.Pooled outcomes of interest included pain intensity and physical disability.The results showed that respiratory exercises significantly reduced pain intensity (p < .00001) and improved physical disability (p < .00001). The main findings... Read More »
Level 1 Meta Analysis
8%
Synopsis: Ninety-six patients with rotator cuff tears smaller than 3 cm were randomized to receive either arthroscopic rotator cuff repair (ARCR) with leukocyte-poor platelet-rich plasma (LP-PRP) injection (n=48) or ARCR without PRP (n=48).The primary outcome was the retear rate, assessed via MRI at six months.Secondary outcomes included pain (VAS), functional scores (ASES, SANE), and sleep quality (PSQI), evaluated at six and twelve months postoperatively.Overall, the study found that the retear rate in the PRP group was significantly lower than in the control group (15.2% vs.34.1%, p = 0.037).However, there were no significant differences in functional outcomes between groups. The findings suggest... Read More »
Level 1 RCT
8%
Synopsis: Six studies involving 517 patients with neck pain were included in this systematic review and meta-analysis, comparing cervical manipulations to thoracic or cervicothoracic manipulations.Pooled outcomes of interest included pain intensity, neck disability, and cervical range of motion.The analysis revealed no significant differences in pain reduction, disability improvement, or cervical range of motion between the intervention groups. Moderate to very... Read More »
Level 1 Meta Analysis
8%
Synopsis: One hundred seventy-two patients undergoing total knee arthroplasty for osteoarthritis were randomized to receive either 5 mg melatonin (n=86) or 125 mg vitamin C placebo (n=86).The primary outcome was the Pittsburgh Sleep Quality Index (PSQI).Secondary outcomes included patient-reported measures of pain and physical function, opioid prescriptions, medication compliance, and adverse events.Outcomes were assessed at both 6 weeks and 90 days.Overall, the results showed no significant differences in PSQI or secondary outcomes between the melatonin and placebo groups at either time point. The findings suggest... Read More »
Level 1 RCT
8%
Synopsis: One-hundred-fourteen patients with isolated ACL rupture were randomized to receive a bone–patellar tendon–bone (BPTB) graft (n = 58) or a hamstring graft (n = 56).The primary outcome was side-to-side anterior laxity measured with the KT-1000 arthrometer.Secondary outcomes included isokinetic knee-extension/flexion strength, Lachman and pivot-shift tests, KOOS, Tegner and Lysholm scores, and Kellgren–Lawrence (KL) osteoarthritis grade.Outcomes were assessed up to a mean of 19 years (range 18–20).Overall, the study revealed no significant between-group difference in KT-1000 laxity.However, hamstring-graft knees showed a 10.7 % lower peak flexion torque and 17.2 % lower total flexion work at 60 deg/s.Patient-reported scores, clinical laxity tests, and KL OA grades were similar. These findings suggest... Read More »
Level 1 RCT
4%
Synopsis: 101 patients with an acute Achilles tendon rupture were randomized to one of two groups: a surgical group, wherein surgical repair was performed and early weight-bearing was encouraged, or a non-surgical group, wherein patients were treated conservatively and early weight-bearing was also encouraged.The purpose of this study was to evaluate these two treatment methods with respect to functional outcomes. Results indicated that... Read More »
Level 2 RCT
4%
Synopsis: This systematic review and meta-analysis included 24 randomized controlled trials with 1711 participants diagnosed with sciatica due to lumbar disc herniation.It compared surgical treatment, primarily discectomy, to non-surgical treatments and epidural steroid injections.The primary outcomes assessed were leg pain and disability, while secondary outcomes included adverse events, back pain, quality of life, and treatment satisfaction.The pooled results indicated that discectomy provided moderate reductions in leg pain in the short term, with diminishing benefits over time.Effects on disability were smaller, showing only minor improvements.The long-term outcomes revealed no significant differences between surgical and non-surgical treatments. These findings suggest... Read More »
Level 1 Meta Analysis