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Acetaminophen Plus Ibuprofen, Codeine, Hydrocodone, or Oxycodone for Musculoskeletal Pain Relief
April 2021
Acetaminophen Plus Ibuprofen, Codeine, Hydrocodone, or Oxycodone for Musculoskeletal Pain Relief
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
A Randomized Trial Comparing the Efficacy of Five Oral Analgesics for Treatment of Acute Musculoskeletal Extremity Pain in the Emergency Department
Ann Emerg Med. 2021 Mar;77(3): 345-356.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Six hundred patients presenting to the 2 urban center emergency departments with acute musculoskeletal pain in ≥1 extremities lasting for >7 days and which the attending physician was willing to administer oral analgesics were randomized to receive either of the 5 oral analgesic combinations: (1) 400 mg ibuprofen plus 1,000 mg acetaminophen; (2) 800 mg ibuprofen plus 1,000 mg acetaminophen; (3) 30...
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