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Volume:19 Issue:1 Number:4 ISSN#:2563-5476
RCT
ACE Report #13388
Ace Report Cover General Orthopaedics

Acetaminophen Plus Ibuprofen, Codeine, Hydrocodone, or Oxycodone for Musculoskeletal Pain Relief


How to Cite

OrthoEvidence. Acetaminophen Plus Ibuprofen, Codeine, Hydrocodone, or Oxycodone for Musculoskeletal Pain Relief. ACE Report. 2021;19(1):4. Available from: https://myorthoevidene.com/AceReport/Report/13388

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

A Randomized Trial Comparing the Efficacy of Five Oral Analgesics for Treatment of Acute Musculoskeletal Extremity Pain in the Emergency Department

Ann Emerg Med. 2021 Mar;77(3): 345-356.

Contributing Authors: PE Bijur BW Friedman E Irizarry AK Chang EJ Gallagher

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Synopsis

Six hundred patients presenting to the 2 urban center emergency departments with acute musculoskeletal pain in ≥1 extremities lasting for >7 days and which the attending physician was willing to administer oral analgesics were randomized to receive either of the 5 oral analgesic combinations: (1) 400 mg ibuprofen plus 1,000 mg acetaminophen; (2) 800 mg ibuprofen plus 1,000 mg acetaminophen; (3) 30...

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