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Oxycodone/Acetaminophen vs. Acetaminophen Alone for Musculoskeletal Pain Refractory to Ibuprofen
September 2021
Oxycodone/Acetaminophen vs. Acetaminophen Alone for Musculoskeletal Pain Refractory to Ibuprofen
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
A randomized controlled trial of oxycodone/acetaminophen versus acetaminophen alone for emergency department patients with musculoskeletal pain refractory to ibuprofen.
Acad Emerg Med. 2021;28: 859–865.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Of the 393 acute musculoskeletal pain patients who received 600mg ibuprofen, 154 were unresponsive and were subsequently randomized to receive oral oxycodone/acetaminophen (n=77) or acetaminophen alone (n=77) for pain relief. The primary outcome of interest was the improvement in pain scores on a 0-10 point scale 2 hours post-treatment. Secondary outcomes included adequacy of analgesia, satisfacti...
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