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Volume:100 Issue:1 Number:1 ISSN#:2564-2537
ACE Report #13933
Ace Report Cover General Orthopaedics

Oxycodone/Acetaminophen vs. Acetaminophen Alone for Musculoskeletal Pain Refractory to Ibuprofen

How to Cite

OrthoEvidence. Oxycodone/Acetaminophen vs. Acetaminophen Alone for Musculoskeletal Pain Refractory to Ibuprofen. ACE Report. 2021;100(1):1. Available from: https://myorthoevidence.com/AceReport/Report/13933

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

A randomized controlled trial of oxycodone/acetaminophen versus acetaminophen alone for emergency department patients with musculoskeletal pain refractory to ibuprofen.

Acad Emerg Med. 2021;28: 859–865.

Contributing Authors: BW Friedman E Irizarry C Feliciano AJ Izzo L Borrayes A Restivo V Costa PE Bijur

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Of the 393 acute musculoskeletal pain patients who received 600mg ibuprofen, 154 were unresponsive and were subsequently randomized to receive oral oxycodone/acetaminophen (n=77) or acetaminophen alone (n=77) for pain relief. The primary outcome of interest was the improvement in pain scores on a 0-10 point scale 2 hours post-treatment. Secondary outcomes included adequacy of analgesia, satisfacti...

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