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ACE Report #12033
Ace Report Cover Trauma

OTA 2019: IV Ibuprofen Reduces Opioid Consumption in Trauma Patients

Study Type:Therapy
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Intravenous Ibuprofen Reduces Opioid Consumption in Acute Pain Management for Orthopaedic Trauma Patients

Contributing Authors: Russell Weisz AA Fokin Amy Flynt Ines Macias-Perez Leo Pavliv Maggie Crawford Ivan Puente

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


Ninety-nine orthopaedic trauma patients were randomized to received either IV Ibuprofen (Caldolor) or placebo every 6 hours for 48 hours within admission. Outcomes included pain on the Numeric Rating Scale, opioid consumption, time to first narcotic administration. Interestingly, though IV Ibuprofen did not significantly affect pain scores, it did significantly reduce opioid consumption and tIme t...

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