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RCT
ACE Report #10443
Ace Report Cover Cannabis

Nabilone effective in reducing headache in medication overuse headach patients compared to ibuprofen


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Nabilone for the treatment of medication overuse headache: results of a preliminary double-blind, active-controlled, randomized trial

J Headache Pain. 2012 Nov;13(8):677-84. doi: 10.1007/s10194-012-0490-1

Contributing Authors: SC L. A. G. Pini A Ferrari P Sarchielli I Tiraferri M Ciccarese M Zappaterra

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Synopsis

30 patients diagnosed with medication overuse headache were randomly assigned to receive either nabilone or ibuprofen for each treatment period. This cross-over study consisted of two 8-week treatment periods, each with 1 week of washout before, and a 2-week discontinuation period at the end of the study. Patients were assessed for the reduction in headache frequency, pain intensity, duration, dai...

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