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Vol:130 Issue:1 Number:1 ISSN#:2564-2537
ACE Report #13949
Ace Report Cover Pediatric Orthopaedics

Safety & Efficacy of Ibuprofen in Children with Musculoskeletal Injuries

How to Cite

OrthoEvidence. Safety & Efficacy of Ibuprofen in Children with Musculoskeletal Injuries. ACE Report. 2021;130(1):1. Available from:

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Efficacy and safety of ibuprofen in children with musculoskeletal injuries: A systematic review and meta-analysis of randomized controlled trials.

Medicine (Baltimore). 2021 Jul 2;100(26): e26516.

Contributing Authors:
J Jin X Wang J Wang Z Wan

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Five randomized controlled trials including 1034 children with musculoskeletal injuries were included in this meta-analysis comparing oral ibuprofen to other oral analgesics. The primary outcomes of interest included the change in Visual Analog Scale (VAS) pain scores, the proportion of patients requiring additional analgesia, and the proportion of patients achieving adequate analgesia. Secondary ...

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