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Use of Combination Paracetamol and Ibuprofen in Postoperative Pain after Total Knee Arthroplasty
February 2022
Use of Combination Paracetamol and Ibuprofen in Postoperative Pain after Total Knee Arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The Use of Combination Paracetamol and Ibuprofen in Postoperative Pain after Total Knee Arthroplasty, a Randomized Controlled Trial.
Pain Physician. 2021 Dec;24(8): E1199-E1204.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Thirty-six patients with knee osteoarthritis scheduled for a total knee arthroplasty were randomized to receive a combination of intravenous paracetamol and ibuprofen (n=12), paracetamol only (n=12) or ibuprofen only (n=12) for the management of post-operative pain. Outcomes of interest included pain intensity during rest, while walking, and at full knee flexion on a numeric pain rating scale (NRS...
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