Zoledronic acid reduces number of skeletal-related events in new multiple myeloma patients

Lancet Oncol. 2011 Aug;12(8):743-52. doi: 10.1016/S1470-2045(11)70157-7. Epub 2011 Jul 21

Oral ibandronic acid inferior to IV zoledronic acid for metastatic breast cancer to bone

Lancet Oncol. 2014 Jan;15(1):114-22. doi: 10.1016/S1470-2045(13)70539-4.

Tranexamic acid reduces blood transfusion requirements during surgery

BMJ. 2012 May 17;344:e3054. doi: 10.1136/bmj.e3054

IV tranexamic acid reduces blood loss and transfusion rate in primary THA

Orthopedics. 2016 Sep 1;39(5):e883-92

AAOS 2016: TXA vs. epsilon-aminocaproic acid provide comparable outcomes after TKA

Tranexamic acid is effective in reducing blood loss, while maintaining safety, in THA

Arch Orthop Trauma Surg. 2013 Jul;133(7):1017-27. doi: 10.1007/s00402-013-1761-2. Epub 2013 Apr 25

Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA

Clin Orthop Relat Res. 2011 Oct;469(10):2874-80. Epub 2011 Apr 22

AAOS 2016: Interim evaluation of tranexamic acid vs placebo in acetabular fracture surgery

TKA: Topical Fibrin Spray and Tranexamic acid reduce blood loss

J Bone Joint Surg Br. 2007 Mar;89(3):306-9

IA-TXA effective compared to placebo for blood loss and transfusion reduction in TKA

J Knee Surg. 2018 Jan;31(1):56-67

COA2017: IA TXA and IV TXA demonstrate similar results for blood loss in total hip arthroplasty

Tranexamic acid effectively reduces blood loss after TKA without adverse events

Knee Surg Sports Traumatol Arthrosc. 2014 Aug;22(8):1849-58

Efficacy of Floseal vs. tranexamic acid vs. control for bleeding control in patients undergoing TKA

Clinics (Sao Paulo). 2019 Nov 25;74:e1186.

3 doses of tranexamic acid more effective regimen in TKA

Clin Orthop Relat Res. 2012 Sep;470(9):2605-12. doi: 10.1007/s11999-012-2310-y. Epub 2012 Mar 15.

Efficacy of various tranexamic acid administration techniques to reduce blood loss in TKA

Knee Surg Sports Traumatol Arthrosc. 2014 Dec;22(12):3181-90.

AAOS2018: IV TXA reduced blood loss in total shoulder arthroplasty

Tranexamic acid is safe and effective in reducing blood loss in TKA

J Bone Joint Surg Am. 2012 Jul 3;94(13):1153-9. doi: 10.2106/JBJS.K.00873

AAOS2017: Tranexamic acid appears safe and effective in fracture surgery

TKR: Topical application of tranexamic acid reduces postoperative blood loss

J Bone Joint Surg Am. 2010 Nov 3;92(15):2503-13.

Intravenous and topical tranexamic acid have similar efficacy in TKA

Arch Orthop Trauma Surg. 2015 Apr;135(4):573-88.