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Less Pain with Intra-Articular Hyaluronic Acid Injection for Knee Osteoarthritis Compared to Placebo
February 2025
Less Pain with Intra-Articular Hyaluronic Acid Injection for Knee Osteoarthritis Compared to Placebo
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Less Pain with Intra-Articular Hyaluronic Acid Injections for Knee Osteoarthritis Compared to Placebo: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
Pharmaceuticals (Basel) . 2024 Nov 20;17(11):1557. doi: 10.3390/ph17111557.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eighteen randomized controlled trials including 3,851 patients with knee osteoarthritis were included in this systematic review and meta-analysis comparing intra-articular hyaluronic acid (HA) injections versus placebo. Pooled outcomes of interest included the Visual Analogue Scale (VAS) for pain and the Western Ontario McMaster Osteo-Arthritis Index (WOMAC) subscales for pain, stiffness, and func...
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