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AAOS 2025: Tranexamic Acid for ORIF of Acetabular & Pelvic Fractures
March 2025
AAOS 2025: Tranexamic Acid for ORIF of Acetabular & Pelvic Fractures
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:N/A
Journal Level of Evidence:N/A
Utilization of Tranexamic Acid in Open Reduction Internal Fixation of Acetabular and Pelvic Fractures: A Systematic Review and Meta-Analysis
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CONFERENCE ACE REPORTS
This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
Ten studies involving 1,213 patients with pelvic and acetabular fractures were included in this systematic review and meta-analysis comparing TXA use versus no TXA in ORIF procedures. Pooled outcomes of interest included intraoperative blood loss, surgical time, transfusion rates, and VTE incidence. TXA use significantly reduced estimated blood loss and operative time compared to controls. Howeve...
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