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Comparable Efficacy of Hyaluronic Acid and Biologic Injections for Early Knee Osteoarthritis
March 2025
Comparable Efficacy of Hyaluronic Acid and Biologic Injections for Early Knee Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Similar efficacy of intra-articular hyaluronic acid injections and other biologically active injections in patients with early stages knee osteoarthritis: a level I meta-analysis.
Arch Orthop Trauma Surg . 2024 Dec 18;145(1):68.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Four randomized controlled trials (RCTs) including 390 patients with early-stage knee osteoarthritis (KL I-II) were included in this systematic review and meta-analysis comparing intra-articular hyaluronic acid (HA) injections with other biologically active injections such as platelet-rich plasma (PRP) and corticosteroids (CSs). Pooled outcomes of interest included the visual analogue scale (VAS),...
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