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The Safety and Effectiveness of Tranexamic Acid in Lumbar Interbody Fusion Surgery
April 2025
The Safety and Effectiveness of Tranexamic Acid in Lumbar Interbody Fusion Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The Safety and Effectiveness of Tranexamic Acid in Lumbar Interbody Fusion Surgery: An Updated Meta-analysis of Randomized Controlled Trials
World Neurosurg . 2022 Oct:166:198-211.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Twelve randomized controlled trials including 1088 patients undergoing PLIF surgery were included in this systematic review and meta-analysis comparing tranexamic acid (TXA) vs. placebo. Pooled outcomes of interest included intraoperative blood loss, total blood loss, hidden blood loss, operative time, postoperative drainage, postoperative hemoglobin and hematocrit levels, length of hospital stay,...
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