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Effect of Oral Tranexamic Acid vs Placebo on Postoperative Bleeding in Spinal Surgery
January 2025
Effect of Oral Tranexamic Acid vs Placebo on Postoperative Bleeding in Spinal Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Effect of oral tranexamic acid on postoperative bleeding in spinal surgery: a randomized controlled trial.
Ann Med Surg (Lond) . 2024 Jun 10;86(8):4483-4487.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
A total of 120 patients undergoing spinal surgery were randomized to receive either 1.5 g of oral tranexamic acid (n=60) or a placebo (n=60) 2 hours before surgery. The primary outcome of interest was intraoperative blood loss. Secondary outcomes included postoperative blood loss, hospital stay length, incidence of nausea or vomiting, and postoperative coagulation measures such as hemoglobin level...
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