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31%
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100%
7%
Synopsis: 39 patients with distal radius fractures undergoing open reduction and internal fixation (ORIF) with a volar locking plate were randomized to receive 2 weeks of post-operative immobilization with a plaster splint or no immobilization.The primary outcome of interest was pain as measured on a Visual Analog Scale.Secondary outcomes included tramadol (opioid) use, DASH score, range of motion (wrist flexion-extension; forearm rotation), patient satisfaction, wrist edema and incidence of complications.Follow up was performed up to 6 months. The results from... Read More »
Level 2 RCT
3%
Synopsis: Five randomized controlled trials were included in this meta-analysis which sought to investigate the efficacy of mesenchymal stem cell injections in patients with knee osteoarthritis.Included studies featured various control groups, including placebo injection, hyaluronic acid injection, and no injection, as well as various concomitant treatments, including high tibial osteotomy, microfracture, platelet rich plasma injection and hyaluronic acid injection.Accordingly, clinical heterogeneity was assumed.Data was pooled from 12-24 month time points. Analyses on visual... Read More »
Level 2 Meta Analysis
3%
Synopsis: 135 patients admitted for total knee replacement were randomized to receive patient controlled analgesia with morphine with either an additional continuous femoral nerve block (FNB), an additional single-shot femoral nerve block, or control (no femoral nerve block).The primary outcome of interest was quadriceps strength recovery (QSR).Secondary outcomes of interest included pain on a Visual Analog Scale (VAS), knee range of motion, thigh diameter, the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) index, the Short Form 36 (SF-36) questionnaire, opioid consumption and length of stay.Follow up was performed during inpatient stay, and at 6 weeks, 6 months and 12 months.Results revealed significantly favourable quadriceps recovery in closed chain contractions at all time points, and in open chain reactions at 6 weeks, in favour of the control group.Knee range of motion was significantly in favour of the control group.No significant differences in morphine consumption, length of stay, thigh diameter, VAS pain score, or SF-36 scores were observed among the three groups. Patients in the... Read More »
Level 2 RCT
2%
Synopsis: 60 patients with Kellgren-Lawrence grade I-II knee osteoarthritis were randomized to treatment with either intraarticular hyaluronic acid or oral hyaluronic acid.Patients allocated to IAHA were administered three weekly injection, and patients allocated to oral HA were given daily tablets to take for 40 days.Outcome measures included pain on a visual analog scale and the American Knee Society Score. Within-group improvement from... Read More »
Level 2 RCT
2%
Synopsis: 84 adult patients with symptomatic isolated interstitial supraspinatus tears were randomized to receive infiltration with platelet rich plasma (PRP) or normal saline.A total of two injections were administered separated by 1 month.The primary outcome of interest was the change in lesion volume.Secondary outcomes of interest included pain on a Visual Analog Scale (VAS), the Single Assessment Numerical Evaluation (SANE), Constant score, the American Shoulder and Elbow Surgeons (ASES) score, the incidence of adverse events and the performance of surgical repair.Follow up was performed at 7 and 12 months after the first injection.Results revealed no significant differences between the PRP and control groups in the change in lesion volume, VAS pain, SANE score, Constant score, and ASES score.The incidence of adverse events was significantly higher in the PRP group. No significant difference... Read More »
Level 1 RCT
2%
Synopsis: 23 randomized controlled trials were included in this meta-analysis which compared component alignment, operative time, length of stay and blood loss between cases of total knee arthroplasty completed with patient-specific instrumentation and cases completed with conventional instrumentation.Absolute deviation and incidence of outliers did not significantly differ between groups for overall coronal lower limb alignment, coronal and sagittal femoral component alignment, and coronal and sagittal tibial component alignment.While absolute deviation in axial femoral component alignment was lower among PSI groups, the difference between groups in outliers in axial femoral component alignment was not significant.Operative time was statistically significantly shorter among PSI groups by approximately 7.5 minutes, and blood loss was statistically significantly lower among PSI groups by approximately 83mL. Length of stay... Read More »
Level 1 Meta Analysis
2%
Synopsis: 99 pediatric patients with an extra-articular finger fracture were randomized to treatment with either buddy taping or splinting for 3 weeks.The primary purpose of this study was to determine if buddy taping was noninferior to splinting for the incidence of secondary displacement, at a noninferiorty margin of a 5% increase.The rates of secondary displacement were 1.9% in the buddy taping group and 6.4% in the splinting group, and the upper limit of 95% confidence interval for the risk difference was below 5%, which suggested noninferiority. In addition, early... Read More »
Level 2 RCT
1%
Synopsis: 673 patients undergoing primary or a staged bilateral total knee arthroplasty (900 procedures) were randomized to receive thromboprophylactic treatment either based on their level of risk for deep venous thrombosis (DVT), or according to a routine anticoagulation protocol.The purpose of this study was to compare these two protocols on the resulting incidence of deep vein thrombosis and wound complications. Results after 1... Read More »
Level 1 RCT
1%
Synopsis: 14 studies, including 8 randomized controlled trials, were included in this meta-analysis which had the purpose of evaluating the prophylactic effects of preventative neuromuscular training in female athletes afflicted with anterior cruciate ligament injuries.The four types of exercise in the training program – balance, proximal control, strength, and plyometrics – were evaluated in subgroup analyses to determine efficacy in terms of number of anterior cruciate ligament injuries incurred during the intervention.The results of this study indicated that strength and proximal control training offered the greatest benefits in terms of preventing injury.However, no significant reduction was seen in the incidence of injuries in patients who engaged in balance or plyometric activities in comparison to those who did not. Additionally, subgroup analysis... Read More »
Author verified Level 2 Meta Analysis
1%
Synopsis: 460 patients with a Gustilo-Anderson type II-III open fracture of the lower limb were randomized to postoperative wound management with either negative pressure wound therapy or standard dressings.Patients were followed up for patient-reported disability and quality of life measures over 12 months, as well as incidences of infection and wound complications over 30 days. Results demonstrated no... Read More »
Level 2 RCT