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Evidence Series
Topical TXA found safe and effective for reduction of blood loss and transfusion in TKA
Orthopedics. 2015 May 1;38(5):315-24.
Similar efficacy with EACA and TXA for reduction of blood loss in patients undergoing TKA
J Orthop Traumatol. 2019 Jul 18;20(1):28.
Non-inferior efficacy of topical TXA to IV TXA in total knee arthroplasty patients
J Arthroplasty. 2014 Aug;29(8):1528-31
TXA efficacy in perioperative spinal surgery bleeding
Spine J. 2015 Apr 1;15(4):752-761.
Multi-dose oral TXA in total knee arthroplasty reduces blood loss with no increase in complication
Int J Surg. 2019 May;65:45-51.
Tranexamic acid reduces blood loss and transfusions in TKA and THA
BMC Res Notes. 2013 May 7;6:184. doi: 10.1186/1756-0500-6-184
Low- and high-dose TXA effective in reducing blood loss and transfusion needs in TKA
BMC Musculoskelet Disord. 2013 Dec 5;14:340. doi: 10.1186/1471-2474-14-340
IV and topical TXA superior to placebo for hematological outcomes after PLIF
World Neurosurg. 2019 Feb;122:e821-e827.
TXA Reduces Blood Loss in Surgeries for Fractures of the Pelvis, Acetabulum and Proximal Femur
J Orthop Trauma. 2019 Aug;33(8):371-376.
IV & topical TXA similarly safe & effective for reducing blood loss and transfusion in TKA
J Orthop. 2016 Mar 26;13(3):127-31
Similar blood loss and lower cost with oral TXA vs. both IA TXA and IV TXA in total hip arthroplasty
J Arthroplasty. 2018 Mar;33(3):786-793
Efficacy of combined IV/IA TXA administration in simultaneous bilateral TKA
Knee. 2015 Mar;22(2):131-5
Low-dose tranexamic acid does not reduce blood loss or transfusion rate in spinal surgery
J Neurosurg Anesthesiol. 2011 Oct;23(4):290-6. doi: 10.1097/ANA.0b013e31822914a1
Intravenous, intraarticular irrigation, and drain administration of TXA in TKA
J Arthroplasty. 2014 Aug;29(8):1521-4