Topical TXA Reduces Blood Loss and Improves Blood Chemistry After Total Knee Replacement Surgery
Topical tranexamic acid in cemented primary total knee arthroplasty without tourniquet: a prospective randomized study.Eur J Orthop Surg Traumatol. 2020.Aug;30(6):1003-1008.
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Two hundred and thirty patients undergoing a cemented total knee arthroplasty without tourniquet were randomized into receiving either topical tranexamic acid (TXA) or control. The primary outcome of interest was total amount of blood loss. Secondary outcomes of interest included hemoglobin and hematocrit levels, length of hospital stay, transfusion rates, and operation time. Furthermore, knee ran...
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