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Volume:9 Issue:9 Number:23 ISSN#:2564-2537
Author Verified
ACE Report #12331
Ace Report Cover General Orthopaedics

Topical TXA Reduces Blood Loss and Improves Blood Chemistry After Total Knee Replacement Surgery

How to Cite

OrthoEvidence. Topical TXA Reduces Blood Loss and Improves Blood Chemistry After Total Knee Replacement Surgery. ACE Report. 2020;9(9):23. Available from: https://myorthoevidence.com/AceReport/Report/12331

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Topical tranexamic acid in cemented primary total knee arthroplasty without tourniquet: a prospective randomized study.

Eur J Orthop Surg Traumatol. 2020.Aug;30(6):1003-1008.

Contributing Authors: M Morales Santias J Mas Martinez J Sanz-Reig E Martínez Gimenez C Verdu Román D Bustamante Suarez de Puga

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Interview with Dr Javier Sanz Reig


Two hundred and thirty patients undergoing a cemented total knee arthroplasty without tourniquet were randomized into receiving either topical tranexamic acid (TXA) or control. The primary outcome of interest was total amount of blood loss. Secondary outcomes of interest included hemoglobin and hematocrit levels, length of hospital stay, transfusion rates, and operation time. Furthermore, knee ran...

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