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IV TXA Reduces Blood Loss & Transfusion Rate in Hip Fracture Surgery
May 2021
IV TXA Reduces Blood Loss & Transfusion Rate in Hip Fracture Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Single dose of tranexamic acid effectively reduces blood loss and transfusion rates in elderly patients undergoing surgery for hip fracture: a randomized controlled trial
Bone Joint J. 2021 Mar;103-B(3): 442-448.Synopsis
One hundred and sixty-five elderly patients scheduled to receive a cemented hemiarthroplasty for a subcapital hip fracture (n=64) or intramedullary nailing procedure for intertrochanteric fracture (n=101) were randomized to receive intravenous tranexamic acid (TXA; n=77) or a normal saline placebo (n=88) for the reduction of blood loss and transfusion rates. Outcomes of interest included total blo...
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