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Volume:8 Issue:8 Number:18 ISSN#:2563-5476
RCT
ACE Report #12298
Ace Report Cover General Orthopaedics

No Significant Differences in Blood Loss or Clinical Outcomes with IA-TXA in ACL Reconstruction


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Intra-articular Administration of Tranexamic Acid Has No Effect in Reducing Intra-articular Hemarthrosis and Postoperative Pain After Primary ACL Reconstruction Using a Quadruple Hamstring Graft: A Randomized Controlled Trial.

Orthop J Sports Med. 2020 Jul; 8(7): 2325967120933135.

Contributing Authors: JW Lee SG Kim SH Kim HW Cho JH Bae

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Synopsis

Sixty patients scheduled for an anterior cruciate ligament (ACL) reconstruction for the treatment of an ACL tear were randomized to receive an intra-operative intra-articular injection of tranexamic acid (TXA) or no treatment. The primary outcome of interest was blood loss, calculated using hemoglobin levels. Secondary outcomes of interest included pain on a Visual Analog Scale (VAS), patellar cir...

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