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TXA Reduces Blood Loss in Surgeries for Fractures of the Pelvis, Acetabulum and Proximal Femur
October 2019
TXA Reduces Blood Loss in Surgeries for Fractures of the Pelvis, Acetabulum and Proximal Femur
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:2
Tranexamic Acid Use in Open Reduction and Internal Fixation of Fractures of the Pelvis, Acetabulum, and Proximal Femur: A Randomized Controlled Trial
J Orthop Trauma. 2019 Aug;33(8):371-376.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Ninety-three adult patients with fractures of the pelvis, acetabulum or proximal femur and scheduled for an open reduction and internal fixation procedure were randomized to receive either 2 doses of peri-operative tranexamic acid (TXA) or no TXA administration. The primary outcomes of interest included total blood loss, the change in hematocrit and hemoglobin levels from baseline, and transfusion...
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