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9%
Synopsis: Ten randomized controlled trials were included in this meta-analysis that compared pain and functional outcomes between intraarticular platelet-rich plasma injection (PRP) and either intraarticular hyaluronic acid (HA) injections or saline injections in knee osteoarthritis treatment.Outcomes were assessed at 6 and 12 months postinjection.In comparison to HA injections, PRP injections demonstrated similar pain and functional outcomes at 6 months postinjection, and significantly better pain and functional outcomes at 12 months postinjection.The effect sizes compared to HA for pain and function at 12 months exceeded the MCID, however, these findings should be interpreted with caution as only a few studies could be pooled for these outcomes. Results from one... Read More »
Level 1 Meta Analysis
7%
Synopsis: Fourteen randomized controlled trials were included in this network meta-analysis on the use of six different non-operative modalities - high-energy focused extracorporeal shockwave therapy, low-energy focused extracorporeal shockwave therapy, radial extracorporeal shockwave therapy, transcutaneous electrical nerve stimulation, therapeutic ultrasound, and ultrasound-guided needling - compared to control intervention for patients with chronic calcific tendinitis of the shoulder. Network meta-analysis indicated that the modalities which demonstrated a significantly greater reduction in pain and calcific deposit resolution relative to control were ultrasound-guided needling, radial extracorporeal shockwave therapy, and high-energy focused extracorporeal shockwave therapy. Read More »
Level 1 Meta Analysis
4%
Synopsis: 120 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were randomized to one of three intra-articular injection groups: platelet rich plasma, hyaluronic acid, or ozone.The purpose of this study was to compare visual analog scores (VAS) for pain and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores for pain, stiffness, and function over a 12-month follow-up.The results demonstrated a marked decrease in all outcome measures within the first month in all three groups, followed by a regression at subsequent follow-ups.Between-group differences were identified, with lower scores generally observed in the PRP and HA groups compared to the ozone group at 1, 3, and 6 months.By 12 months, scores in the ozone group had returned to baseline, while scores in the PRP and HA groups were lower, relatively. Also at 12... Read More »
Level 2 RCT
2%
Synopsis: 504 patients with a grade I or II ankle sprain seeking care in an acute care setting were randomized to usual care, including protection, rest, ice, compression, and elevation (PRICE) with or without participation in a standardized physiotherapy program.The purpose of this study was to evaluate if patients who participated in the physiotherapy program demonstrated significantly better function on the Foot and Ankle Outcome Score (FAOS) over a 6-month follow-up. No significant differences... Read More »
Level 2 RCT
2%
Synopsis: 467 patients managed with a below-knee plaster cast for a foot or ankle fracture were randomized to either subcutaneous nadroparin 2850IE daily, subcutaneous fondaparinux 2.5mg daily, or no thromboprophylaxis intervention (control).Patients were screened during follow-up for cases of deep vein thrombosis and pulmonary embolism. Results demonstrated significantly... Read More »
Conference Report
2%
Synopsis: 100 patients scheduled for total knee arthroplasty were randomized to either a posterior cruciate-retaining implant or a posterior-cruciate substituting implant.Patients were assessed for function, quality of life, and the incidence of reoperation over a 10-year follow-up. No significant differences... Read More »
Level 2 RCT
2%
Synopsis: 35 patients scheduled for matrix-induced autologous chondrocyte implantation were randomized to either an accelerated or delayed weight-bearing postoperative rehabilitation protocol.Groups were compared for clinical outcome measures, radiological outcomes, and the incidence of complications.Results demonstrated no significant differences between groups in any clinical outcome measures, including the KOOS, SF-36, VAS pain, knee ROM, and knee strength in extension and flexion. Results on the... Read More »
Level 2 RCT
2%
Synopsis: 400 patients, 50 years of age or older, with lumbar spinal stenosis, were randomized to epidural injection of corticosteroid plus lidocaine, or lidocaine alone.Patients could request crossover to the other group after 6 weeks but remained blinded to initial and subsequent treatment.Patients were assessed for disability and leg pain over 12 months. Results demonstrated no... Read More »
Level 2 RCT
2%
Synopsis: Three randomized controlled trials were selected for meta-analysis investigating the comparative effects of repair and conservative treatment for rotator cuff tears.Pain and function, assessed on the Constant score, were assessed at 1-year follow-up.Results demonstrated a significantly greater reduction in pain among conservative treatment groups compared to repair groups; change in function after 1 year did not significantly differ between groups. Differences between groups... Read More »
Level 2 Meta Analysis
1%
Synopsis: 111 patients eligible for primary total knee arthroplasty (TKA) were randomly allocated to receive either a posterior stablized (PS) post/cam tibial insert or a more congruent cruciate-substituting (CS) insert.This study aimed to compare the clinical outcomes during the postoperative period and radiographic and functional outcomes at a minimum 2-year follow-up between the two devices.At 2-years the PS and CS groups demonstrated equivalent functional and radiographic outcomes.Tourniquet time was significantly shorter in the CS group.Intraoperative estimated blood loss, hemoglobin, and units of blood transfused were not significantly different, however, in a subgroup analysis of males, the CS group required significantly fewer units of blood transfused. Read More »
Level 2 RCT