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8%
Synopsis: 29 studies were included in this meta-analysis comparing operative and non-operative treatment for acute Achilles tendon ruptures.The primary outcome of interest was the rate of re-rupture.Secondary outcomes included the rate of complications, functional outcomes, time to return to sports and time to return to work.The results revealed a significantly lower rate of re-rupture, but a higher rate of complications, in the operative group compared to the non-operative group.Similar findings to the primary analyses were observed in the sensitivity analyses based on early and late weight bearing status, high quality studies and studies conducted after the year 2000.There were no significant differences in re-rupture rate in studies utilizing accelerated functional rehabilitation. There was no... Read More »
Level 1 Meta Analysis
8%
Synopsis: Five randomized controlled trials were included in this meta-analysis which sought to investigate the efficacy of mesenchymal stem cell injections in patients with knee osteoarthritis.Included studies featured various control groups, including placebo injection, hyaluronic acid injection, and no injection, as well as various concomitant treatments, including high tibial osteotomy, microfracture, platelet rich plasma injection and hyaluronic acid injection.Accordingly, clinical heterogeneity was assumed.Data was pooled from 12-24 month time points. Analyses on visual... Read More »
Level 2 Meta Analysis
4%
Synopsis: 149 patients (168 heels) with chronic plantar fasciitis were randomized to receive extracorporeal shockwave treatment or conservative treatment consisting of non-steroidal anti-inflammatory drugs, orthotics, physical therapy, an exercise program and/or a local cortisone injection.Over 5 to 6 years, patients in the shockwave group had significantly greater improvements in pain and function than the conservative treatment group.The patients who received shockwave therapy were also significantly less likely to experience a recurrence of symptoms compared to the conservative treatment group. The results therefore... Read More »
Level 2 RCT
4%
Synopsis: 198 patients with plantar fasciitis were randomized to receive 1 of 3 treatment modalities to determine the efficacy of a novel foot brace (the EZstep) in alleviating heel pain.Patients either received nonsteroidal anti-inflammatory drugs (NSAIDs) and wore an EZStep foot brace, or received NSAIDs while undergoing physiotherapy, or received NSAIDs, physiotherapy, and local steroid injections. Following assessments over... Read More »
Author verified Level 2 RCT
4%
Synopsis: 30 patients with lateral epicondylitis and 30 patients with plantar fasciitis were randomized to determine the efficacy of platelet-rich plasma injection in the treatment of both conditions.A 1:1 ratio of patients from each cohort were allocated to receive either injection of PRP or corticosteroid, and were followed-up for 6 weeks thereafter in outcomes of pain and function.Results at 6 weeks in patients with plantar fasciitis indicated that while both treatments significantly improved pain and function, patients treated with PRP had a greater degree of improvement. In patients with... Read More »
Level 2 RCT
4%
Synopsis: 50 patients with sacroiliac joint pain were randomized to receive injection treatments of either intra-articular prolotherapy (5% dextrose water) or intra-articular corticosteroid to evaluate the sustained pain relief effects of each treatment.The trial used the Numerical Rating System (NRS) and the Oswestry disability index (ODI) for pain and disability respectively. The study found... Read More »
Level 2 RCT
4%
Synopsis: 21 patients diagnosed with chronic recalcitrant plantar fasciitis were randomized to receive either dextrose prolotherapy (DP) or autologous platelet-rich plasma (PRP) injection therapy.The purpose was to evaluate the efficacies of these treatments and additionally, to assess whether one is more effective.Results at 28 weeks indicated that both treatments significantly improved total Foot Function Index scores versus baseline but no between-group differences were found. Nevertheless, PRP provided... Read More »
Author verified Level 2 RCT
4%
Synopsis: 28 patients with Achilles tendinopathy were randomized to undergo eccentric heel-drop exercises, following either a do-as-tolerated protocol or the standard Alfredson protocol.The purpose of this study was to compare the two treatment approaches with respect to pain, function and satisfaction after 6 weeks.Results indicated that both study protocols yielded significant improvements in clinical outcomes at both 3 and 6 weeks, except for the standard group at 3 weeks, wherein Victorian Institute of Sport Assessment-Achilles (VISA-A) scores had significantly deteriorated.There were no significant differences between groups in pain intensity or functional outcomes at 6 weeks. Patient satisfaction was... Read More »
Level 2 RCT
4%
Synopsis: 24 patients with chronic rotator cuff disorders/tendinopathy were randomized to receive either a self-managed exercise programme, or usual physiotherapy.This pilot study was conducted to evaluate a new research methodology comparing the clinical efficacy between these treatments.The proportion of participants willing to be randomized was excellent, with no complications during the recruitment process. Results indicated excellent... Read More »
Level 2 RCT
4%
Synopsis: 40 patients with chronic unilateral plantar fasciitis, who had failed extensive, traditional, nonoperative management, were randomly assigned into 1 of 2 treatment groups to determine if platelet rich plasma injections effectively treated chronic unilateral plantar fasciitis.Patients either received a single ultrasound guided injection of autologous platelet-rich plasma or a 40 mg injection of DepoMedrol cortisone. The results of... Read More »
Author verified Level 2 RCT