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Comparison of no orthosis, removable orthosis, and plaster cast after miniopen carpal tunnel release
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Synopsis: 249 patients scheduled for mini-open carpal tunnel release were randomized to postoperative management with either no orthosis, a removable orthosis, or cast immobilization for 10-14 days.Patients were assessed for disability, pain, function, and the incidence of complications over a 12-month follow-up. Results demonstrated no... Read More »
Author verified Level 2 RCT
2%
Decompression of no statistical benefit over sham, and no clinical benefit over exercise for SIS
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Synopsis: 210 patients with shoulder impingement syndrome were randomized to one of three treatment groups: arthroscopic subacromial decompression, diagnostic arthroscopy (sham surgery), or an exercise therapy program.Primary outcomes were pain at rest and pain during activity, and follow-up was performed over 24 months.Analyses demonstrated no statistically significant differences in pain scores between the arthroscopic subacromial decompression group and the diagnostic arthroscopy group. Additionally, while statistically... Read More »
Level 2 RCT
2%
Patient-reported pain and function over 52 weeks between unloader brace vs. placebo for knee OA
②
Synopsis: 150 patients with Kellgren-Lawrence or Ahlback grade I-II knee osteosrthritis were randomized to either an active or placebo unloader brace.Patients were followed for 52 weeks for outcome related to patient-reported function on the Knee Society Score (KSS) and Knee Injury and Osteoarthritis Outcome Score (KOOS).In general, changes from baseline to 52 weeks in scores were greater in the unloader brace group compared to placebo brace group, with statistical significance demonstrated for the KOOS pain, sport/rec, and QoL subscales. However, difference between... Read More »
Level 2 RCT
1%
Low level laser therapy provides significant pain relief for plantar fasciitis by 8 weeks
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Synopsis: 69 patients with unilateral plantar fasciitis were randomized to receive either low level laser therapy (LLLT) or placebo treatment.The purpose of the study was to determine if LLLT resulted in improved patient pain management compared to placebo up to 8 weeks after treatment.The primary outcome of interest was VAS heel pain score, and secondary outcomes included plantar fascia thickness, quality of life (FFI score), and patient satisfaction.Results demonstrated a significantly greater reduction in pain, reduction in plantar fascial thickness and rate of high patient satisfaction compared to the placebo group. No significant difference... Read More »
Level 2 RCT
1%
Effect of platelet concentrate on union of long-bone delayed union versus no treatment control
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Synopsis: 40 patients with a delayed union of a long bone fracture were randomized to either receive or not receive autologous platelet concentrate application at the site of the fracture.The purpose of this study was to determine if there was a significant difference in the rate of progression to union within 36 weeks of injury between groups. Results demonstrated no... Read More »
Level 2 RCT
1%
Metal ions and moderate pseudotumor development reduced with large- vs. small-head MoM THA
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Synopsis: 185 patients scheduled for metal-on-metal (MoM) total hip arthroplasty (THA) were randomized to either large-head or small-head articulation.Main outcomes of concern in this study included whole blood cobalt and chromium ion concentrations and the incidence of pseudotumor development on MRI over a 5-year follow-up.Cobalt levels were significantly lower in the large-head group compared to the small-head group at 36, 48, and 60 months postoperatively, while chromium levels were significantly lower in the large-head group compared to the small-head group at 12 and 48 months postoperatively. The incidence of... Read More »
Author verified Level 2 RCT
1%
Testing of noninferiority of PT vs partial meniscectomy on knee fuction in meniscal tear treatment
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Synopsis: 321 patients with a nonobstructive mensical tear were randomized to either an 8-week physical therapy program or to arthroscopic partial meniscectomy.The primary purpose of this study was to determine if the PT group was noninferior to the APM for outcome on the International Knee Documentation Committee (IKDC) subjective score at a noninferiority margin of 8pts. When analyzed in... Read More »
Author verified Level 2 RCT
1%
No significant difference in 2-year quality-of-life between SB and DB ACL reconstruction
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Synopsis: 120 patients scheduled for anterior cruciate ligament reconstruction were randomized to either double-bundle (DB) or single-bundle (SB) reconstruction.Primary outcome was the Knee Injury and Osteoarthritis Outcome Score (KOOS) Quality of Life (QoL) subscale.Secondary outcomes included the remaining KOOS subscales, manual and instrumented tests for knee laxity, Tegner activity scale, and incidence of adverse events.Follow-up was scheduled for 1 and 2 years postoperatively.For the primary outcome, results demonstrated no significant differences between the DB and SB group for improvement in KOOS QoL scores. Additionally, no statistically... Read More »
Level 2 RCT
1%
No analgesic advantage of liposomal bupivacaine over ropivacaine for infiltration analgesia in TKA
②
Synopsis: 29 patients scheduled bilateral knee arthroplasty were randomized to intervention in one knee with liposomal bupivacaine periarticular infiltration analgesia and in the other knee with ropivacaine periarticular infiltration analgesia.Patients were assessed over the first two postoperative days for pain, subjective function, and incidence of complications. No significant differences... Read More »
Level 2 RCT
1%
Long-term outcome of surgery favoured over physiotherapy alone for subacromial impingement syndrome
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Synopsis: 87 patients with subacromial impingement were randomized to one of three treatment groups: arthroscopic acromioplasty, open acromioplasty, or to a physiotherapy program.Patients were followed-up for a minimum of 10 years after intervention, with outcomes related to subjective function (Constant score), shoulder range of motion, shoulder strength in abduction, and ultrasonic and radiographic evaluations.At final follow-up, Constant score was significant greater in the open acromioplasty compared to physical therapy alone, and range of motion in elevation was significantly greater in both the arthroscopic and open acromioplasty groups compared to the physical therapy alone. However, range of... Read More »
Level 2 RCT