Combination of dexketoprofen/tramadol reduces postoperative pain vs. monotherapy in THA

Br J Anaesth. 2016 Feb;116(2):269-76.

Multi-dose oral TXA in total knee arthroplasty reduces blood loss with no increase in complication

Int J Surg. 2019 May;65:45-51.

No difference in infection risk with single vs. multidose antibiotics in orthopedic implant surgery

Clin Orthop Relat Res. 2019 Jul;477(7):1577-1590.

Increasing number of IV TXA doses further improves efficacy without increasing VTE risk in THA

J Arthroplasty. 2018 Sep;33(9):2940-2945. doi: 10.1016/j.arth.2018.04.024

Patellofemoral pain: High-dose high-repetition vs low dose, low repetition exercise

Physiotherapy. 2013 Jun;99(2):126-31. doi: 10.1016/j.physio.2012.05.009. Epub 2012 Jul 24

Nabiximols improves multiple sclerosis spasticity compared to placebo over 12 weeks

Eur J Neurol. 2011 Sep;18(9):1122-31. doi: 10.1111/j.1468-1331.2010.03328.x

Delta-9 THC Improves Pain and Spasticity Compared to Placebo for Multiple Sclerosis Over 2 Weeks

CMAJ. 2012 Jul 10;184(10):1143-50. https://dx.doi.org/10.1503/cmaj.110837

Single-dose intra-articular bupivacaine significantly reduces pain after knee arthroscopy

Knee Surg Sports Traumatol Arthrosc. 2014 Jul;22(7):1517-28

Low-dose tranexamic acid does not reduce blood loss or transfusion rate in spinal surgery

J Neurosurg Anesthesiol. 2011 Oct;23(4):290-6. doi: 10.1097/ANA.0b013e31822914a1

Titrated THC and CBD does not significantly improve spasticity compared to placebo over 4 weeks

J Neurol. 2015 Nov;262(11):2520-7

Single and multiple level thoracic manipulation for chronic neck pain

Neuropsychiatr Dis Treat. 2015 Jan 12;11:137-44.

Single-dose epidural DepoDur is a safe and effective analgesic after knee arthroplasty

J Bone Joint Surg Am. 2006 Feb;88(2):273-81

Low-dose intraoperative CT imaging does not reduce pedicle screw accuracy in spinal fusion

Eur Spine J. 2017 Nov;26(11):2818-2827

Cannabis extract and THC improve pain in patients with multiple sclerosis

Lancet. 2003 ;362(9385):1517-26.

OTA 2014: High-dose vitamin D vs. placebo in deficient patients with long bone fracture

Percutaneous vertebroplasty improves spinal stability in patients with multiple myolema

Eur Spine J. 2012 May;21(5):912-9. Epub 2011 Dec 16.

ISAKOS2017: Similar 12-week outcome between high- and low-dose steroid for shoulder stiffness

Low-dose ketamine reduces pain and opioid consumption following orthopaedic surgery

Br J Anaesth. 2019 Sep;123(3):325-334.

Zoledronic acid reduces number of skeletal-related events in new multiple myeloma patients

Lancet Oncol. 2011 Aug;12(8):743-52. doi: 10.1016/S1470-2045(11)70157-7. Epub 2011 Jul 21

Similar ROM and clinical scores between high & low-dose corticosteroid for shoulder stiffness

J Shoulder Elbow Surg. 2017 Feb;26(2):209-215