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Extended Surgical Antiobiotic Prophylaxis Vs Single Dose For Total Hip Or Knee Arthroplasty
May 2024
Extended Surgical Antiobiotic Prophylaxis Vs Single Dose For Total Hip Or Knee Arthroplasty
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A
Extended Surgical Antibiotic Prophylaxis Not Superior To A Single Dose In Total Hip And Knee Revision Arthroplasty: A Multicenter Open-Lavel Randomized Controlled Trial
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CONFERENCE ACE REPORTS
This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
Seven hundred twenty-one patients undergoing aseptic hip or knee revision arthroplasty were randomized to receive either a single dose of cefazolin (n=364) or an extended 5-day regimen of cefazolin (n=357). The primary outcome of interest was the incidence of prosthetic joint infection (PJI) within 12 weeks post-surgery. Secondary outcomes included rates of other infections, adverse reactions, hos...
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