LOGIN
COA 2020: Factors Predicting Multiple Surgeries for Paediatric Osteomyelitis - The CORTICES group
Read Full Publication
March 2025
COA 2020: Factors Predicting Multiple Surgeries for Paediatric Osteomyelitis - The CORTICES group
Study Type:Retrospective Observational Study
OE Level Evidence:N/A
Journal Level of Evidence:N/A
Predicting Which Children with Osteomyelitis Require Secondary Surgery– Results from the CORTICES multicenter database
Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
CONFERENCE ACE REPORTS
This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
A total of nine hundred and ninety-six paediatric patients who had osteomyelitis were included in the study. Sixteen percent of included patients required more than 1 surgery; factors associated with an increase in probability of needed more than 1 surgery for treatment of OM included a higher white blood cell count, peak C-reative protein, peak erythrocyte sedimentation rate and lower platelet count.
Why was this study needed now?
It is important to understand musculoskeletal infections in children, including paediatric osteomyelitis. Surgical treatment is often used, and assessing factors that can increase the likelihood of requiring more than 1 surgery is crucial.
What was the principal research question?
What factors can predict whether children with paediatric osteomyelitis (OM) require multiple surgery for treatment?
Study Characteristics
-
Population:
Children with paediatric osteomyelitis.
Intervention:
N/A
Comparison:
N/A
Outcomes:
Number of surgeries required to treat paediatric OM.
Methods:
Eighteen paediatric centres were used. To make comparisons, Wilcoxon two-sample tests were conducted for quantitative variables. Chi-squared tests were conducted to make comparisons for binary variables. Multivariable logistic regression was also carried out for predicting clinical factors associated with increased odds of requiring more than 1 surgery for treatment of OM. Receiver operating curve analysis was conducted and a probability algorithm was developed.
Time:
Not reported.
What were the important findings?
- Of a total of 996 patients with OM, 16% required more than 1 surgery.
- Results revealed that significant differences were found for factors including white blood cell count, lowest platelet count, peak C-Reactive protein, and peak erythrocyte sedimentation rate.
- Children with all of the above mentioned risk factors had a 62% increase in probability of needing more than 1 surgery, where as a child with no risk factors had a 4% probability.
What should I remember most?
Children with paediatric OM are at an increased probability of requiring multiple surgeries if they have higher white blood cell count, C-Reactive protein, and peak erythrocyte sedimentation rate along with lower platelet values.
How will this affect the care of my patients?
It can inform clinicians and physicians in helping make clinical decisions during the treatment of OM in paediatric patients.
Learn about our AI Driven
High Impact Search Feature
Our AI driven High Impact metric calculates the impact an article will have by considering both the publishing journal and the content of the article itself. Built using the latest advances in natural language processing, OE High Impact predicts an article’s future number of citations better than impact factor alone.
Continue
Join the Conversation
Please Login or Join to leave comments.
Orthopaedic Surgeon - Libya
Very interesting