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Analgesia with intra-articular bupivacaine in total hip arthroplasty

J Arthroplasty. 2014 Dec;29(12):2457-61

RCT Arthroplasty Lower Extremity Hip Pain Zimmer VerSys Fiber Bupivacaine Analgesia IA Injected Saline - Hide

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Intra-articular hylastan vs intra-articular steroid in knee OA treatment

Knee Surg Sports Traumatol Arthrosc. 2014 Jul;22(7):1684-92

RCT Osteoarthritis Lower Extremity Knee Arthritis Genzyme Hylastan Arthrocentesis IA Injection Of Methylprednisolone Acetate Steroid - Hide

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Efficacy of joint lavage and/or IA CS injection in knee OA treatment; 2x2 factorial trial

Arthritis Rheum. 1999 Mar;42(3):475-82

RCT Osteoarthritis Lower Extremity Knee Arthritis Roussel Injection IA Placebo Lavage - Hide

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Higher OMERACT-OARSI response rate following IA-HA injection vs steroid or placebo

Br J Sports Med. 2016 Jan;50(2):84-92

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Corticosteroid HA Injection IA-HA Injections Of Hyaluronic Acid Low-Molecular-Weight Placebo Saline Steroid Viscosupplementation - Hide

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AAOS 2016: Subacromial inferior to IA corticosteroid injection for frozen shoulder

RCT Shoulder & Elbow Capsulitis Upper Extremity Shoulder Bone Subacromial Corticosteroid Injection IA Triamcinolone Acetonide - Hide

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Comparison for IA corticosteroid versus saline injection following lavage for knee OA

Rheumatology (Oxford). 2003 Dec;42(12):1477-85

RCT Osteoarthritis Lower Extremity Knee Arthritis Arthroscopy Injection IA Corticosteroid Lavage Methylprednisolone Acetate Placebo Saline - Hide

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Addition of IA steroid injection to exercise not efficacious for knee OA inflammation

Osteoarthritis Cartilage. 2016 May;24(5):814-21

RCT Osteoarthritis Lower Extremity Knee Joint Tibiofemoral Arthritis Inflammation Pfizer Methylprednisolone Lidocaine Steroid Injection Corticosteroid Depomedrol Exercise IA Injection Isotonic Saline Physical Therapy Placebo Ultrasound - Hide

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IA glucocorticioid not associated with decrease in synovitis when compared to IA saline for knee OA

Osteoarthritis Cartilage. 2017 Apr;25(4):481-491

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Synovitis Methylprednisolone Lidocaine Glucocorticoid Injection IA Saline Ultrasound-Guided - Hide

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ISAKOS2017: Efficacy of IA steroid injection in the treatment of frozen shoulder

Meta-analysis Shoulder & Elbow Upper Extremity Shoulder Steroid Injection IA Sham Injection - Hide

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IA bupivacaine and morphine reduces pain in arthroscopic knee surgery compared to placebo

BMJ Open. 2015 Jun 15;5(6):e006815

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Pain Morphine Analgesia Arthroscopic Surgery Arthroscopy IA Bupivacaine Placebo Saline Single-Dose - Hide

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IA injection of morphine + bupivacaine vs. morphine alone for analgesia after arthroscopy

PLoS One. 2015 Oct 16;10(10):e0140512

Meta-analysis Sports Medicine Lower Extremity Knee Pain Bupivacaine Morphine Analgesia Anterior Cruciate Arthroscopic Arthroscopy IA Injection Immediate Single-Dose - Hide

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Automated vs. conventional ultrasound-guided intra-articular CS injection for hip pain

J Ultrasound Med. 2016 Jun;35(6):1259-67.

RCT General Orthopaedics Lower Extremity Hip Pain Carticept Medical Automated Injection Conventional Ultrasound-Guided - Hide

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IA-HA injection as adjunct to microfracture surgery for osteochondral lesions of the talus

Knee Surg Sports Traumatol Arthrosc. 2016 Apr;24(4):1243-9

RCT Foot & Ankle Lesion Lower Extremity Bone Talus Seikagaku Artz Injections HA Injection Hyaluronic Acid IA-HA Microfracture Surgery MRI - Hide

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AAOS 2016: IV+IA TXA significantly reduces blood loss compared to IV TXA alone in TKA

RCT Arthroplasty Lower Extremity Knee Tranexamic Acid Anaesthesia Injection Blood Loss IA TXA IV TXA Saline - Hide

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Similar changes in clinical & radiographic results after 2 years with IA steroid vs saline

Arthritis Rheum. 2003 Feb;48(2):370-7

RCT Osteoarthritis Lower Extremity Knee Arthritis Injections IA Corticosteroid IA Saline Steroid Triamcinolone Acetonide - Hide

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OARSI 2016: IA 20mg & 40mg extended-release triamcinolone acetonide vs placebo for knee OA

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Flexion Therapeutics Injection Extended-Release Triamcinolone Acetonide Placebo - Hide

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Effective pain relief with intraaarticular ketorolac/hyaluronic acid in cases of knee OA

J Back Musculoskelet Rehabil. 2011;24(1):31-8

RCT Osteoarthritis Women Lower Extremity Knee Arthritis Inflammation Pain Ketorolac Hyaluronic Acid IA HA Injections - Hide

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Single-dose intra-articular bupivacaine significantly reduces pain after knee arthroscopy

Knee Surg Sports Traumatol Arthrosc. 2014 Jul;22(7):1517-28

Meta-analysis General Orthopaedics Lower Extremity Knee Pain Bupivacaine Analgesia Analgesic Arthroscopic Surgery Arthroscopy IA Placebo Reduction Single-Dose - Hide

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Hydrodilation versus intra-articular and subacromial injections for adhesive capsulitis

J Shoulder Elbow Surg. 2016 Mar;25(3):376-83

RCT Shoulder & Elbow Capsulitis Upper Extremity Shoulder Bone Subacromial Lidocaine Triamcinolone Adhesive Injection Hydrodilation Injected Saline - Hide

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Consistent pain improvement from 4-24 weeks with hyaluronic acid in knee osteoarthritis

Osteoarthritis Cartilage. 2011 Jun;19(6):611-9

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Pain Hylan Hyaluronan Synvisc Orthovisc Injections Hyaluronate Hyaluronic Acid Injection IA Placebo IAHA Viscosupplementation - Hide

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Analgesia with intra-articular bupivacaine in total hip arthroplasty

Intra-articular hylastan vs intra-articular steroid in knee OA treatment

Efficacy of joint lavage and/or IA CS injection in knee OA treatment; 2x2 factorial trial

Higher OMERACT-OARSI response rate following IA-HA injection vs steroid or placebo

AAOS 2016: Subacromial inferior to IA corticosteroid injection for frozen shoulder

Comparison for IA corticosteroid versus saline injection following lavage for knee OA

Addition of IA steroid injection to exercise not efficacious for knee OA inflammation

IA glucocorticioid not associated with decrease in synovitis when compared to IA saline for knee OA

ISAKOS2017: Efficacy of IA steroid injection in the treatment of frozen shoulder

IA bupivacaine and morphine reduces pain in arthroscopic knee surgery compared to placebo

IA injection of morphine + bupivacaine vs. morphine alone for analgesia after arthroscopy

Automated vs. conventional ultrasound-guided intra-articular CS injection for hip pain

IA-HA injection as adjunct to microfracture surgery for osteochondral lesions of the talus

AAOS 2016: IV+IA TXA significantly reduces blood loss compared to IV TXA alone in TKA

Similar changes in clinical & radiographic results after 2 years with IA steroid vs saline

OARSI 2016: IA 20mg & 40mg extended-release triamcinolone acetonide vs placebo for knee OA

Effective pain relief with intraaarticular ketorolac/hyaluronic acid in cases of knee OA

Single-dose intra-articular bupivacaine significantly reduces pain after knee arthroscopy

Hydrodilation versus intra-articular and subacromial injections for adhesive capsulitis

Consistent pain improvement from 4-24 weeks with hyaluronic acid in knee osteoarthritis

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