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Intra-articular hylastan vs intra-articular steroid in knee OA treatment

Knee Surg Sports Traumatol Arthrosc. 2014 Jul;22(7):1684-92

RCT Osteoarthritis Lower Extremity Knee Arthritis Genzyme Hylastan Arthrocentesis IA Injection Of Methylprednisolone Acetate Steroid - Hide

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Analgesia with intra-articular bupivacaine in total hip arthroplasty

J Arthroplasty. 2014 Dec;29(12):2457-61

RCT Arthroplasty Lower Extremity Hip Pain Zimmer VerSys Fiber Bupivacaine Analgesia IA Injected Saline - Hide

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Efficacy of joint lavage and/or IA CS injection in knee OA treatment; 2x2 factorial trial

Arthritis Rheum. 1999 Mar;42(3):475-82

RCT Osteoarthritis Lower Extremity Knee Arthritis Roussel Injection IA Placebo Lavage - Hide

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Addition of IA steroid injection to exercise not efficacious for knee OA inflammation

Osteoarthritis Cartilage. 2016 May;24(5):814-21

RCT Osteoarthritis Lower Extremity Knee Joint Tibiofemoral Arthritis Inflammation Pfizer Methylprednisolone Lidocaine Steroid Injection Corticosteroid Depomedrol Exercise IA Injection Isotonic Saline Physical Therapy Placebo Ultrasound - Hide

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AAOS 2016: Subacromial inferior to IA corticosteroid injection for frozen shoulder

RCT Shoulder & Elbow Capsulitis Upper Extremity Shoulder Bone Subacromial Corticosteroid Injection IA Triamcinolone Acetonide - Hide

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Higher OMERACT-OARSI response rate following IA-HA injection vs steroid or placebo

Br J Sports Med. 2016 Jan;50(2):84-92

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Corticosteroid HA Injection IA-HA Injections Of Hyaluronic Acid Low-Molecular-Weight Placebo Saline Steroid Viscosupplementation - Hide

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ISAKOS2017: Efficacy of IA steroid injection in the treatment of frozen shoulder

Meta-analysis Shoulder & Elbow Upper Extremity Shoulder Steroid Injection IA Sham Injection - Hide

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Comparison for IA corticosteroid versus saline injection following lavage for knee OA

Rheumatology (Oxford). 2003 Dec;42(12):1477-85

RCT Osteoarthritis Lower Extremity Knee Arthritis Arthroscopy Injection IA Corticosteroid Lavage Methylprednisolone Acetate Placebo Saline - Hide

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IA glucocorticioid not associated with decrease in synovitis when compared to IA saline for knee OA

Osteoarthritis Cartilage. 2017 Apr;25(4):481-491

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Synovitis Methylprednisolone Lidocaine Glucocorticoid Injection IA Saline Ultrasound-Guided - Hide

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IA bupivacaine and morphine reduces pain in arthroscopic knee surgery compared to placebo

BMJ Open. 2015 Jun 15;5(6):e006815

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Pain Morphine Analgesia Arthroscopic Surgery Arthroscopy IA Bupivacaine Placebo Saline Single-Dose - Hide

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IA-HA injection as adjunct to microfracture surgery for osteochondral lesions of the talus

Knee Surg Sports Traumatol Arthrosc. 2016 Apr;24(4):1243-9

RCT Foot & Ankle Lesion Lower Extremity Bone Talus Seikagaku Artz Injections HA Injection Hyaluronic Acid IA-HA Microfracture Surgery MRI - Hide

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Similar changes in clinical & radiographic results after 2 years with IA steroid vs saline

Arthritis Rheum. 2003 Feb;48(2):370-7

RCT Osteoarthritis Lower Extremity Knee Arthritis Injections IA Corticosteroid IA Saline Steroid Triamcinolone Acetonide - Hide

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AAOS 2016: IV+IA TXA significantly reduces blood loss compared to IV TXA alone in TKA

RCT Arthroplasty Lower Extremity Knee Tranexamic Acid Anaesthesia Injection Blood Loss IA TXA IV TXA Saline - Hide

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Automated vs. conventional ultrasound-guided intra-articular CS injection for hip pain

J Ultrasound Med. 2016 Jun;35(6):1259-67.

RCT General Orthopaedics Lower Extremity Hip Pain Carticept Medical Automated Injection Conventional Ultrasound-Guided - Hide

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IA injection of morphine + bupivacaine vs. morphine alone for analgesia after arthroscopy

PLoS One. 2015 Oct 16;10(10):e0140512

Meta-analysis Sports Medicine Lower Extremity Knee Pain Bupivacaine Morphine Analgesia Anterior Cruciate Arthroscopic Arthroscopy IA Injection Immediate Single-Dose - Hide

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Intra-operative intra-articular analgesia injection provides reduced post-operative pain

Knee. 2009 Aug;16(4):280-4. Epub 2009 Mar 18

RCT Arthroplasty Osteoarthritis Lower Extremity Knee Arthritis Pain Bupivacaine Morphine Betamethasone Analgesia Injection Post-Operative Saline - Hide

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Effective pain relief with intraaarticular ketorolac/hyaluronic acid in cases of knee OA

J Back Musculoskelet Rehabil. 2011;24(1):31-8

RCT Osteoarthritis Women Lower Extremity Knee Arthritis Inflammation Pain Ketorolac Hyaluronic Acid IA HA Injections - Hide

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Consistent pain improvement from 4-24 weeks with hyaluronic acid in knee osteoarthritis

Osteoarthritis Cartilage. 2011 Jun;19(6):611-9

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Pain Hylan Hyaluronan Synvisc Orthovisc Injections Hyaluronate Hyaluronic Acid Injection IA Placebo IAHA Viscosupplementation - Hide

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Multi-injection HA appears to be more effective than single-injection HA versus saline for knee OA

BMC Musculoskelet Disord. 2017 Dec 21;18(1):542

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Ferring HA Hyaluronic Acid Injections Placebo Injection Placebo Saline Single Injection - Hide

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Hydrodilation versus intra-articular and subacromial injections for adhesive capsulitis

J Shoulder Elbow Surg. 2016 Mar;25(3):376-83

RCT Shoulder & Elbow Capsulitis Upper Extremity Shoulder Bone Subacromial Lidocaine Triamcinolone Adhesive Injection Hydrodilation Injected Saline - Hide

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Intra-articular hylastan vs intra-articular steroid in knee OA treatment

Analgesia with intra-articular bupivacaine in total hip arthroplasty

Efficacy of joint lavage and/or IA CS injection in knee OA treatment; 2x2 factorial trial

Addition of IA steroid injection to exercise not efficacious for knee OA inflammation

AAOS 2016: Subacromial inferior to IA corticosteroid injection for frozen shoulder

Higher OMERACT-OARSI response rate following IA-HA injection vs steroid or placebo

ISAKOS2017: Efficacy of IA steroid injection in the treatment of frozen shoulder

Comparison for IA corticosteroid versus saline injection following lavage for knee OA

IA glucocorticioid not associated with decrease in synovitis when compared to IA saline for knee OA

IA bupivacaine and morphine reduces pain in arthroscopic knee surgery compared to placebo

IA-HA injection as adjunct to microfracture surgery for osteochondral lesions of the talus

Similar changes in clinical & radiographic results after 2 years with IA steroid vs saline

AAOS 2016: IV+IA TXA significantly reduces blood loss compared to IV TXA alone in TKA

Automated vs. conventional ultrasound-guided intra-articular CS injection for hip pain

IA injection of morphine + bupivacaine vs. morphine alone for analgesia after arthroscopy

Intra-operative intra-articular analgesia injection provides reduced post-operative pain

Effective pain relief with intraaarticular ketorolac/hyaluronic acid in cases of knee OA

Consistent pain improvement from 4-24 weeks with hyaluronic acid in knee osteoarthritis

Multi-injection HA appears to be more effective than single-injection HA versus saline for knee OA

Hydrodilation versus intra-articular and subacromial injections for adhesive capsulitis

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Region of the Body

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Emerging Treatments

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