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Effectiveness Of Intra-Articular Vancomycin In Preventing Prosthetic Joint Infections In TKA and THA
May 2025
Effectiveness Of Intra-Articular Vancomycin In Preventing Prosthetic Joint Infections In TKA and THA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Effectiveness of intra-articular vancomycin in preventing prosthetic joint infections in hip and knee arthroplasty: A systematic review and meta-analysis of RCT's.
J Orthop . 2025 Jan 4:66:25-33.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Five randomized controlled trials involving 1485 patients undergoing primary hip or knee arthroplasty were included in this systematic review and meta-analysis comparing intra-articular vancomycin powder with standard prophylaxis alone. Pooled outcomes of interest included prosthetic joint infection rates, adverse drug reactions, and deep vein thrombosis. The infection rate was lower in the interv...
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