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Autologous Dermal Fibroblast Injection Reduces Retear Rate After Rotator Cuff Repair

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Ace Report Cover
June 2025

Autologous Dermal Fibroblast Injection Reduces Retear Rate After Rotator Cuff Repair

Vol: 307| Issue: 6| Number:56| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Efficacy of an Autologous Dermal Fibroblast Injection in Reducing the Retear Rate After Arthroscopic Rotator Cuff Repair: A Prospective Randomized Controlled Trial.

Am J Sports Med . 2025 Mar;53(3):592-599.

Contributing Authors:
YK Kim YT Kim YS Won YH Jang ST Hwang J Han S Jeon SH Kim JH Oh

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Synopsis

Seventy-three patients with full-thickness rotator cuff tears >2 cm were randomized to receive either an autologous dermal fibroblasts (ADF) injection during arthroscopic rotator cuff repair (n=36) or arthroscopic rotator cuff repair (ARCR) alone (n=37). The primary outcome was the retear rate at 6 months, assessed by MRI. Secondary outcomes included American Shoulder and Elbow Surgeons (ASES) sco...

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