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Intravenous Injection of Tranexamic Acid in Patients with Pelvic Fractures for Blood Loss
May 2025
Intravenous Injection of Tranexamic Acid in Patients with Pelvic Fractures for Blood Loss
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Intravenous Injection of Tranexamic Acid in Patients with Pelvic Fractures: A Prospective Randomized Trial.
Hip Pelvis . 2025 Mar 1;37(1):64-71.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred patients with Tile B and C pelvic fractures undergoing open reduction and internal fixation were randomized to receive either intravenous tranexamic acid (TXA) 15 mg/kg in 40 mL saline twice, 3 hours apart (n=50), or an equal volume of saline as placebo (n=50). The primary outcome was total perioperative blood loss. Secondary outcomes included hemoglobin and hematocrit changes, transfu...
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