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Osteosarcoma: methotrexate & doxorubicin versus methotrexate, etoposide & ifosfamide

Eur J Cancer. 2007 Mar;43(4):752-61. Epub 2007 Jan 30

RCT Tumour Osteosarcoma Doxorubicin Etoposide-Ifosfamide High-Dose Methotrexate Infusion Preoperative Chemotherapy - Hide

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WCO-IOF: Rituximab positively impacts QOL in patients with rheumatoid arthritis

RCT General Orthopaedics Arthritis Methotrexate Rituximab Therapy - Hide

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Etanercept with methotrexate more effectively maintains low disease activity in RA

Lancet. 2013 Mar 16;381(9870):918-29. doi: 10.1016/S0140-6736(12)61811-X. Epub 2013 Jan 17

RCT Osteoarthritis Arthritis Pfizer Methotrexate Etanercept - Hide

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Juvenile RA: Fewer disease flares with Adalimumab (TNF Antibody)

N Engl J Med. 2008 Aug 21;359(8):810-20

RCT Pediatric Orthopaedics Arthritis Abbott Methotrexate Adalimumab Placebo - Hide

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Ifosfamide not necessary in chemotherapy for nonmetastatic osteosarcoma

J Clin Oncol. 2012 Jun 10;30(17):2112-8. doi: 10.1200/JCO.2011.38.4420. Epub 2012 May 7

RCT Tumour Osteosarcoma Sarcoma Methotrexate Cisplatin Ifosfamide Doxorubicin Chemotherapy Regimen Preoperative - Hide

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RA: Addition of etanercept to methotrexate increases remission rates

Lancet. 2008 Aug 2;372(9636):375-82. Epub 2008 Jul 16

RCT General Orthopaedics Arthritis Wyeth Etanercept Oral Methotrexate - Hide

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WCO-IOF: Rituximab for rheumatoid arthritis positively impacts BMD of femoral neck

RCT General Orthopaedics Bone Femur Neck Arthritis Methotrexate Rituximab Therapy - Hide

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WCO-IOF: Methotrexate may reduce BMD loss in patients with rheumatoid arthritis

RCT General Orthopaedics Osteoporosis Arthritis Methotrexate Leflunomide - Hide

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Muramyl tripeptide in chemotherapy improves overall osteosarcoma survival

J Clin Oncol. 2008 Feb 1;26(4):633-8. doi: 10.1200/JCO.2008.14.0095

RCT Tumour Children Metastasis Osteosarcoma Women Methotrexate Cisplatin Ifosfamide Doxorubicin Chemotherapy Muramyl - Hide

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Patellofemoral pain: High-dose high-repetition vs low dose, low repetition exercise

Physiotherapy. 2013 Jun;99(2):126-31. doi: 10.1016/j.physio.2012.05.009. Epub 2012 Jul 24

RCT Physical Therapy & Rehab Joint Patellofemoral Pain Syndrome High-Dose Low-Dose Medical Exercise Therapy - Hide

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Rheumatoid arthritis: Improvement in clinical outcome similar between 4 drug therapies

Ann Intern Med. 2007 Mar 20;146(6):406-15

RCT General Orthopaedics Arthritis Centocor Schering Schering-Plough Methotrexate Sulfasalazine Infliximab Prednisone Sequential Monotherapy - Hide

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TNF antagonist better in treatment of early rheumatoid arthritis

Lancet. 2009 Aug 8;374(9688):459-66.

RCT General Orthopaedics Arthritis Necrosis Methotrexate Sulfasalazine Hydroxychloroquine Infliximab Factor Antagonist - Hide

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Tocilizumab more effective in reducing rheumatoid arthritis symptoms than adalimumab

Lancet. 2013 May 4;381(9877):1541-50. doi: 10.1016/S0140-6736(13)60250-0. Epub 2013 Mar 18

RCT Osteoarthritis Arthritis Hoffmann-La Roche Roche Methotrexate Adalimumab Subcutaneously Monotherapy Placebo Tocilizumab Intravenously - Hide

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High-dose TXA more effective than low-dose TXA and placebo for reducing blood loss in PLIF

Eur Spine J. 2017 Nov;26(11):2851-2857

RCT Spine Stenosis Axial Skeleton Lumbar Spinal Stenosis Tranexamic Acid Bolus High-Dose TXA Interbody Fusion Low-Dose Placebo Saline - Hide

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OTA 2014: High-dose vitamin D vs. placebo in deficient patients with long bone fracture

RCT Trauma Bone Femur Humerus Tibia Fracture High-Dose Oral Placebo Vitamin - Hide

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Similar ROM and clinical scores between high & low-dose corticosteroid for shoulder stiffness

J Shoulder Elbow Surg. 2017 Feb;26(2):209-215

RCT Shoulder & Elbow Upper Extremity Shoulder Stiffness Lidocaine High-Dose Low-Dose Triamcinolone Acetonide Ultrasound-Guided Intraarticular Injection - Hide

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ISAKOS2017: Similar 12-week outcome between high- and low-dose steroid for shoulder stiffness

RCT Shoulder & Elbow Upper Extremity Shoulder Stiffness Low-Dose Steroid Triamcinolone Acetonide Ultrasound-Guided Injection - Hide

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MTP-PE added to chemotherapy did not improve outcomes in metastatic osteosarcoma patients

Cancer. 2009 Nov 15;115(22):5339-48. doi: 10.1002/cncr.24566

RCT Tumour Children Metastasis Osteosarcoma Cisplatin Ifosfamide Doxorubicin Chemotherapy High-Dose Methotrexate Muramyl - Hide

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No difference between high- and low-dose corticosteroid injection for shoulder pain

Arch Phys Med Rehabil. 2011 Dec;92(12):1951-60. doi: 10.1016/j.apmr.2011.06.033. Epub 2011 Oct 25

RCT Shoulder & Elbow Upper Extremity Shoulder Bone Subacromial Pain Lidocaine Corticosteroid Low-Dose Placebo Subacromial Injection Triamcinolone Acetonide - Hide

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High- and low-dose BM-MSC injection versus control for treatment of knee osteoarthritis

J Transl Med. 2016 Aug 26;14(1):246. doi: 10.1186/s12967-016-0998-2

RCT Osteoarthritis Lower Extremity Knee Arthritis Autologous Bone Marrow Injection Control High-Dose Hyaluronic Acid Low-Dose - Hide

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Osteosarcoma: methotrexate & doxorubicin versus methotrexate, etoposide & ifosfamide

WCO-IOF: Rituximab positively impacts QOL in patients with rheumatoid arthritis

Etanercept with methotrexate more effectively maintains low disease activity in RA

Juvenile RA: Fewer disease flares with Adalimumab (TNF Antibody)

Ifosfamide not necessary in chemotherapy for nonmetastatic osteosarcoma

RA: Addition of etanercept to methotrexate increases remission rates

WCO-IOF: Rituximab for rheumatoid arthritis positively impacts BMD of femoral neck

WCO-IOF: Methotrexate may reduce BMD loss in patients with rheumatoid arthritis

Muramyl tripeptide in chemotherapy improves overall osteosarcoma survival

Patellofemoral pain: High-dose high-repetition vs low dose, low repetition exercise

Rheumatoid arthritis: Improvement in clinical outcome similar between 4 drug therapies

TNF antagonist better in treatment of early rheumatoid arthritis

Tocilizumab more effective in reducing rheumatoid arthritis symptoms than adalimumab

High-dose TXA more effective than low-dose TXA and placebo for reducing blood loss in PLIF

OTA 2014: High-dose vitamin D vs. placebo in deficient patients with long bone fracture

Similar ROM and clinical scores between high & low-dose corticosteroid for shoulder stiffness

ISAKOS2017: Similar 12-week outcome between high- and low-dose steroid for shoulder stiffness

MTP-PE added to chemotherapy did not improve outcomes in metastatic osteosarcoma patients

No difference between high- and low-dose corticosteroid injection for shoulder pain

High- and low-dose BM-MSC injection versus control for treatment of knee osteoarthritis

Date Range

Report Types

Condition

See all (67)

Region of the Body

See all (20)

Specialties

See all (14)

Emerging Treatments

OE Recommends Topics

Multimedia

Journal

Conference Series

Evidence Series

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