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Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces for KOA

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Ace Report Cover
March 2025

Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces for KOA

Vol: 307| Issue: 3| Number:93| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults With Knee Osteoarthritis: The START Randomized Clinical Trial

JAMA . 2021 Feb 16;325(7):646-657.

Contributing Authors:
SP Messier SL Mihalko DP Beavers BJ Nicklas P DeVita JJ Carr DJ Hunter M Lyles A Guermazi KL Bennell RF Loeser

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Synopsis

Three hundred seventy-seven adults with knee osteoarthritis were randomized to receive high-intensity strength training (n=127), low-intensity strength training (n=126), or attention control (n=124). The primary outcomes were knee pain measured by the WOMAC scale and knee joint compressive force during walking. Secondary outcomes included physical function, 6-minute walk distance, joint space widt...

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