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AAOS 2025: 3-Month Infection Rates with Vancomycin and Povidone-Iodine Lavage in High-Risk THA

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Ace Report Cover
March 2025

AAOS 2025: 3-Month Infection Rates with Vancomycin and Povidone-Iodine Lavage in High-Risk THA

Vol: 307| Issue: 3| Number:99| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Three-Month Wound Complication and Infection Rates After Vancomycin Powder and Dilute Povidone Iodine Lavage for Infection Prophylaxis in High-Risk Total Hip Arthroplasty: A Multicenter Randomized Control Trial

Contributing Authors:
WB Macaulay M Meftah J Davis D Waren CA Higuera Rueda NS Piuzzi AK Klika JM Villa DA Dennis HJ Cooper Rs Yoon A Tang BrettR Levine A DeBenedetti AF Chen R Schwarzkopf Hayley E Raymond Braden Vincent Saba Z Alpert Farouk Jarir Khury Vladimir Tress Vinay Aggarwal B Zhang Adriana P. Echevarria Gonzalez Nickelas Huffman Ignacio Pasqualini Olivia Pamela Vyge Yair David Kissin Martin Malik Dylan Oliver Amethia D. Joseph Mia J Fowler Ian S Hong Lenin Fermin Zeynep SerefFerlengez John M Dundon Paul M Lombardi James C Wittig Eileen Poletick William John Long

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CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

Synopsis

Ninety-three patients with periprosthetic joint infection were randomized to receive either rapid 7-day exchange arthroplasty with intra-articular antibiotic irrigation (n=46) or standard two-stage exchange arthroplasty (n=47). The primary outcome of interest was treatment success at 12 months, defined as survival, absence of recurrent PJI, no re-operation on the index joint, completion of Stage 2...

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