
AAOS 2025: 3-Month Infection Rates with Vancomycin and Povidone-Iodine Lavage in High-Risk THA

AAOS 2025: 3-Month Infection Rates with Vancomycin and Povidone-Iodine Lavage in High-Risk THA
Three-Month Wound Complication and Infection Rates After Vancomycin Powder and Dilute Povidone Iodine Lavage for Infection Prophylaxis in High-Risk Total Hip Arthroplasty: A Multicenter Randomized Control Trial
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Synopsis
Ninety-three patients with periprosthetic joint infection were randomized to receive either rapid 7-day exchange arthroplasty with intra-articular antibiotic irrigation (n=46) or standard two-stage exchange arthroplasty (n=47). The primary outcome of interest was treatment success at 12 months, defined as survival, absence of recurrent PJI, no re-operation on the index joint, completion of Stage 2...
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