TKA: Non-weight-bearing passive flexion: Motion metrics improved with high flexion device

J Arthroplasty. 2013 Mar;28(3):429-38. doi: 10.1016/j.arth.2012.07.019. Epub 2012 Dec 6

No significant differences in results between high-flexion and standard PS TKA

Orthopedics. 2015 Mar 1;38(3):e206-12

RCT2: Blood loss with 6h postop flexion after TKA lower than with 3h flexion or extension

Bone Joint J. 2014 Feb;96-B(2):201-9

Comparison of high-flexion knee prostheses

J Bone Joint Surg Am. 2009 Apr;91(4):753-60

Flexed femoral component offers greater postoperative knee flexion in knee arthroplasty

Knee. 2014 Jan;21(1):257-63. doi: 10.1016/j.knee.2012.10.028. Epub 2012 Nov 24

Postoperative knee flexion reduces blood loss after total knee arthroplasty

Knee Surg Sports Traumatol Arthrosc. 2014 Aug;22(8):1859-64

No advantage of splintage in flexion following total knee arthroplasty

Knee. 2008 Jan;15(1):15-9. Epub 2007 Nov 9.

Assessing flexion, pain, weight-bearing flexion following mobile-bearing high-flexion TKR

J Bone Joint Surg Br. 2012 Aug;94(8):1051-7.

RCT1: Knee in flexion following total knee arthoplasty reduces blood loss and transfusion

Bone Joint J. 2014 Feb;96-B(2):201-9

AAOS2017: No clinical/radiographic advantage or disadvantage of high-flexion TKA

Higher ROM achieved with high-flex TKA; no significant effect on functional outcome

Med Sci Monit. 2015 Jun 9;21:1679-86

Role of high flexion implant design for cruciate-retaining TKA

J Arthroplasty. 2014 May;29(5):961-5

Active cranio-cervical flexion exercise can improve muscle control for chronic neck pain

Man Ther. 2014 Feb;19(1):25-31. doi: 10.1016/j.math.2013.05.011.

Postoperative flexion may reduce blood loss and improve ROM following TKA

Knee Surg Sports Traumatol Arthrosc. 2015 Mar;23(3):852-9

Nexgen high flexion design offeres comparable ROM to standard implant for TKA

J Bone Joint Surg Br. 2008 Jan;90(1):37-42

Lower blood loss and increased early ROM with knee flexion vs. extension after TKA

Arch Orthop Trauma Surg. 2017 Feb;137(2):257-265

Tranexamic acid decreases blood loss & transfusion needs compared to knee flexion post-TKA

Knee Surg Sports Traumatol Arthrosc. 2014 Nov;22(11):2756-62.

Short-term effect of extended- vs immediate-release triamcinolone acetonide for knee OA

J Bone Joint Surg Am. 2015 Jun 3;97(11):877-88

Investigating efficacy of extended-release steroid FX006 16mg and 32mg in knee OA treatment

Arthritis Rheumatol. 2018 Feb;70(2):204-211. doi: 10.1002/art.40364

No clinical advantage of high-flexion versus standard prostheses in TKA

J Arthroplasty. 2015 Jun;30(6):980-6