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Single-dose intra-articular bupivacaine significantly reduces pain after knee arthroscopy
Knee Surg Sports Traumatol Arthrosc. 2014 Jul;22(7):1517-28
No difference in infection risk with single vs. multidose antibiotics in orthopedic implant surgery
Clin Orthop Relat Res. 2019 Jul;477(7):1577-1590.
Single-Dose IA ropivacaine reduces pain up to 8 hours post arthroscopic knee surgery
Knee Surg Sports Traumatol Arthrosc. 2016 May;24(5):1651-9
Single-dose epidural DepoDur is a safe and effective analgesic after knee arthroplasty
J Bone Joint Surg Am. 2006 Feb;88(2):273-81
Antiresorptive effects of single zoledronate dose are sustained for 3 years
J Bone Miner Res. 2010 Oct;25(10):2251-5
Evaluating single-dose betamethasone for analgesia after outpatient knee arthroscopy
J Anesth. 2016 Oct;30(5):803-10
Combination of dexketoprofen/tramadol reduces postoperative pain vs. monotherapy in THA
Br J Anaesth. 2016 Feb;116(2):269-76.
Knee OA: Single (1200 mg) and 3/day (400 mg) dose chondroitin are equivalent
Osteoarthritis Cartilage. 2012 Oct 8. pii: S1063-4584(12)00992-2. doi: 10.1016/j.joca.2012.09.017
Single-shot dose and continuous infusion of TXA have similar efficacy in primary TKA
Arch Orthop Trauma Surg. 2015 Apr;135(4):465-71
No significant effect of vitamin D3 supplementation on fracture union in hypovitaminosis patients
Bone Joint J. 2017 Nov;99-B(11):1520-1525
TKA: preoperative methylprednisolone effective for pain and recovery
Br J Anaesth. 2011 Feb;106(2)
Multi-dose oral TXA in total knee arthroplasty reduces blood loss with no increase in complication
Int J Surg. 2019 May;65:45-51.
Preoperative dose of etoricoxib reduces postoperative morphine consumption
Acta Orthop. 2012 Dec;83(6):642-7. doi: 10.3109/17453674.2012.747053. Epub 2012 Nov 9
Single preoperative dose of pregabalin 150mg offers short analgesic efficacy in PLIF cases
J Clin Anesth. 2016 Jun;31:149-53
Effects of 2.5mg zoledronate are long-lasting and similar to 5mg dose in osteopenic women
J Bone Miner Res. 2014 Jan;29(1):166-72. doi: 10.1002/jbmr.2009.
THR: Single pamidronate dose doesn't prevent development of osteolytic lesions
J Bone Joint Surg Br. 2006 Oct;88(10):1309-15.
TKA: LIA effective short term analgesia in terms of VAS, morphine consumption and function
Knee. 2014 Jun;21(3):636-46