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OTA 2015: LIPUS demonstrates no effect on function or time-to-union after tibial fracture

RCT Trauma Bone Tibia Shaft Fracture IM Low-Intensity Pulse Ultrasound Nails Sham LIPUS - Hide

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Low-intensity pulsed ultrasound may not be clinically beneficial for clavicle fractures

Injury. 2008 Dec;39(12):1444-52. doi: 10.1016/j.injury.2008.04.004. Epub 2008 Jul 25.

RCT Trauma Bone Clavicle Fracture Exogen Naproxen Paracetamol LIPUS Low-Intensity Pulsed Ultrasound - Hide

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Low-intensity pulsed ultrasound improves bone healing in delayed unions of the tibia

BMC Musculoskelet Disord. 2010 Oct 8;11:229. doi: 10.1186/1471-2474-11-229.

RCT Trauma Bone Tibia Shaft Delayed Union Fracture Exogen Smith & Nephew Delayed LIPUS Low-Intensity Pulsed Ultrasound Sham - Hide

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Outcomes of distraction osteogenesis unaltered by low intensity pulsed ultrasound therapy

J Orthop Surg Res. 2018 Aug 17;13(1):205. doi: 10.1186/s13018-018-0907-x

Meta-analysis Trauma Osteogenesis Distraction Low-Intensity Pulsed Ultrasound Reduction Ultrasound Therapy - Hide

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Reduced time to radiographic union with low-intensity pulsed ultrasound vs. placebo

Am J Orthop (Belle Mead NJ). 2012 Feb;41(2):E12-9

Meta-analysis Trauma Fracture Bridging Cortical Fixation LIPUS Low-Intensity Pulsed Ultrasound Placebo - Hide

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The effect of low-intensity pulsed ultrasound on fracture healing

CMAJ. 2002 Feb 19;166(4):437-41

Meta-analysis Trauma Fracture Bridging Cortical LIPUS Low-Intensity Pulsed Ultrasound Physical Therapy Placebo Ultrasound Therapy - Hide

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The effect of pulsed/low-intensity bone growth stimulation in acute fractures

Arch Orthop Trauma Surg. 2014 Aug;134(8):1093-106

Meta-analysis Trauma Lower Extremity Ankle Fracture Bone Growth LIPUS Low-Intensity Pulsed Ultrasound PEMF Placebo Pulsed Electromagnetic Field Therapy Pulsed Electromagnetic Fields Stimulation - Hide

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LIPUS not associated with benefit in post-fracture/osteotomy function or pain

BMJ. 2017 Feb 22;356:j656

Meta-analysis Trauma Fracture Nonunion Pain Control Low-Intensity Pulsed Ultrasound Orthopaedic Osteotomy Sham LIPUS - Hide

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Low-intensity pulsed ultrasound not cost-effective following IM nailing of fresh tibial fracture

Bone Joint J. 2017 Nov;99-B(11):1526-1532

RCT Trauma Bone Tibia Fracture Exogen LIPUS Low-Intensity Pulsed Ultrasound Sham - Hide

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LIPUS improves clinical and radiological outcomes vs sham for complex tibial fractures

Ultrasound Med Biol. 2004 Mar;30(3):389-95.

RCT Trauma Bone Tibia Fracture Exogen Smith & Nephew LIPUS Low-Intensity Pulsed Ultrasound Sham - Hide

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Low Intensity, Long Duration US for symptomatic relief of knee osteoarthritis

J Orthop Surg Res. 2018 Oct 16;13(1):257.

RCT Osteoarthritis Lower Extremity Knee Arthritis - Hide

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Addition of low-intensity pulsed ultrasound to callus distraction beneficial to patients

J Trauma. 2011 Nov;71(5):1376-80. doi: 10.1097/TA.0b013e31821912b2

RCT General Orthopaedics Osteogenesis Distraction LIPUS Low-Intensity Pulsed Ultrasound - Hide

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Similar outcomes in ultrasound and low-level laser therapy for myofascial trigger points

Physiother Res Int. 2014 Sep;19(3):166-75

RCT Physical Therapy & Rehab Muscle Trapezius Low-Level Laser Therapy Placebo Trigger Points Ultrasound - Hide

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LIPUS does not expedite union or functional recovery following tibial fracture fixation

BMJ. 2016 Oct 25;355

RCT Trauma Bone Tibia Shaft Fracture Exogen Smith & Nephew LIPUS Low-Intensity Pulsed Ultrasound Sham - Hide

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Systematic review of the application of LIPUS and PEMF in tibial fracture management

J Athl Train. 2007 Oct-Dec;42(4):530-5

Meta-analysis Trauma Bone Tibia Fracture Electric Current LIPUS Therapy Low-Intensity Pulsed Ultrasound PEMF Placebo Pulsed Electromagnetic Field Therapy - Hide

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Low-intensity pulsed ultrasound elicits faster bone healing after forearm osteotomy

J Hand Surg Am. 2013 Mar;38(3):498-503. doi: 10.1016/j.jhsa.2012.11.032. Epub 2013 Feb 1

RCT Hand & Wrist Upper Extremity Forearm Bone Radius Ulna Smith & Nephew Teijin Pharma LIPUS Therapy Low-Intensity Pulsed Ultrasound Osteotomy - Hide

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Variable evidence & efficacy of low intensity pulsed ultrasonography for fracture healing

BMJ. 2009 Feb 27;338:b351

Meta-analysis General Orthopaedics Fracture Control Low Intensity Pulsed - Hide

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Continuous and pulsed ultrasound show similar efficacy for knee osteoarthritis

Osteoarthritis Cartilage. 2014 Aug;22(8):1090-9

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Continuous Ultrasound Pulsed Ultrasound - Hide

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High-intensity laser therapy versus combined US and TENS in cervical spondylosis treatment

Lasers Med Sci. 2019 Jul;34(5):947-953. doi: 10.1007/s10103-018-2682-7

RCT Physical Therapy & Rehab Nerve Spine Cervical Transcutaneous Electrical Nerve Stimulation High-Intensity Laser Therapy TENS Ultrasound - Hide

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Focused Low-Intensity Pulsed Ultrasound vs. Shortwave Diathermy for Knee Osteoarthritis

Sci Rep. 2022 01-Jul;():. 10.1038/s41598-022-17291-z

RCT Osteoarthritis Appendicular Lower Extremity Knee Joint Tibiofemoral Low-Intensity Pulsed Ultrasound Electrical modality Shortwave diathermy Enraf-Nonius Chongqing Haifu Medical Technology CZG200 Curapulse 970 - Hide

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OTA 2015: LIPUS demonstrates no effect on function or time-to-union after tibial fracture

Low-intensity pulsed ultrasound may not be clinically beneficial for clavicle fractures

Low-intensity pulsed ultrasound improves bone healing in delayed unions of the tibia

Outcomes of distraction osteogenesis unaltered by low intensity pulsed ultrasound therapy

Reduced time to radiographic union with low-intensity pulsed ultrasound vs. placebo

The effect of low-intensity pulsed ultrasound on fracture healing

The effect of pulsed/low-intensity bone growth stimulation in acute fractures

LIPUS not associated with benefit in post-fracture/osteotomy function or pain

Low-intensity pulsed ultrasound not cost-effective following IM nailing of fresh tibial fracture

LIPUS improves clinical and radiological outcomes vs sham for complex tibial fractures

Low Intensity, Long Duration US for symptomatic relief of knee osteoarthritis

Addition of low-intensity pulsed ultrasound to callus distraction beneficial to patients

Similar outcomes in ultrasound and low-level laser therapy for myofascial trigger points

LIPUS does not expedite union or functional recovery following tibial fracture fixation

Systematic review of the application of LIPUS and PEMF in tibial fracture management

Low-intensity pulsed ultrasound elicits faster bone healing after forearm osteotomy

Variable evidence & efficacy of low intensity pulsed ultrasonography for fracture healing

Continuous and pulsed ultrasound show similar efficacy for knee osteoarthritis

High-intensity laser therapy versus combined US and TENS in cervical spondylosis treatment

Focused Low-Intensity Pulsed Ultrasound vs. Shortwave Diathermy for Knee Osteoarthritis

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