OTA 2019: Time to irrigation does not independently increase the risk of infection in open fractures

Saline solution reduces reoperation compared to soap in irrigation of open fractures

N Engl J Med. 2015 Dec 31;373(27):2629-41

Epinephrine diluted irrigation fluid may increase visual acuity for shoulder arthroscopy

Arthroscopy. 2016 Mar;32(3):436-44

Warmed irrigation fluid prevents the development of hypothermia

Arthroscopy. 2009 Jan;25(1):24-9. Epub 2008 Oct 10

Intramedullary canal irrigation may reduce fat emboli in females during TKA

J Arthroplasty. 2015 Mar;30(3):451-5.

Similar rates of hypothermia whether irrigation fluid is warmed or not in shoulder surgery

Arthroscopy. 2014 Feb;30(2):159-64. doi: 10.1016/j.arthro.2013.11.017.

Irrigation solutions and pressures in open fracture management do not significantly influence HRQoL

Bone Joint J. 2018 Jan;100-B(1):88-94

Epinephrine irrigation in shoulder arthroscopy improves surgeon-rated visualization

Arthroscopy. 2015 Jan;31(1):12-8.

Tidal irrigation provides longer lasting pain relief than steroid injection in knee OA

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Irrigation through arthroscopy vs arthrotomy in the management of septic knee arthritis

Knee Surg Sports Traumatol Arthrosc. 2016 Oct;24(10):3155-3162

No effect of gentamicin in irrigation solution for reducing septic arthritis in ACLR

Arch Orthop Trauma Surg. 2014 Feb;134(2):257-61. doi: 10.1007/s00402-013-1910-7. Epub 2013 Dec 10

Norepinephrine useful in reducing hypotension & bradycardic events in rotator cuff repair

Arthroscopy. 2015 May;31(5):800-6

AAOS 2017: Health-related QOL and function deficit remains at 12-month in open fracture patients

OTA 2016: QoL similar between soap/saline, irrigation pressures in open fracture treatment

Intravenous, intraarticular irrigation, and drain administration of TXA in TKA

J Arthroplasty. 2014 Aug;29(8):1521-4

Cost-efficacy analysis of decompression versus irrigation and no treatment for subacromial pain

Bone Joint J. 2019 Jan;101-B(1):55-62. doi: 10.1302/0301-620X.101B1.BJJ-2018-0555.R1

Investigational anti-inflammatory, OMS103HP, provides excellent results for ACLR

Arthroscopy. 2008 Jun;24(6):625-36.

OMS103HP Reduces Pain and Improves Joint function After Arthroscopic Meniscectomy

Arthroscopy; 2011; 27; 1060-1070

Pilot Study - Fluid lavage of open wounds: The need for RCT of irrigation approaches

J Trauma. 2011 Sep;71(3):596-606.

No clinically relevant benefit of subacromial decompression for subacromial shoulder pain

Lancet. 2018 Jan 27;391(10118):329-338. doi: 10.1016/S0140-6736(17)32457-1