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Volume:7 Issue:10 Number:22 ISSN#:2563-5476
ACE Report #12043
Ace Report Cover Trauma

OTA 2019: Time to irrigation does not independently increase the risk of infection in open fractures

Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

The Effect of Time to Irrigation on the Rate of Reoperation in Open Fractures: A Propensity Score-Based Analysis of the Fluid Lavage of Open Wounds (FLOW) Study

Contributing Authors: H Johal D Axelrod S Sprague B Petrisor Sofia Bozovsky M Bhandari

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


Infection is of great concern in open fractures. Traditionally, time to irrigation and debridement has been thought to be important, and six hours has been cited as an ideal time target. However, this is based on basic science studies with limited clinical correlation. In this study, the authors performed a secondary analysis of the Fluid Lavage of Open Wounds (FLOW) Trial data. Patients were matc...

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