Most positive hand surgery RCTs have very fragile results
How to Cite
OrthoEvidence. Most positive hand surgery RCTs have very fragile results. ACE Report. 2019;8(9):31. Available from: https://myorthoevidene.com/AceReport/Report/12011
The Fragility Index in Hand Surgery Randomized Controlled TrialsJ Hand Surg Am. 2019;44(8):698. doi: 10.1016/j.jhsa.2018.10.005. Epub 2018 Nov 9
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The Fragility Index is an important concept when assessing the strength of findings from a positive RCT - essentially, the Fragility Index asks how many patients it would take with an opposite outcome in order for the overall trial results to become non-significant. In this paper, the authors apply this concept to RCTs in hand surgery. They include 5 RCTs with positive findings on a dichotomous pr...
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