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Most positive hand surgery RCTs have very fragile results
September 2019
Most positive hand surgery RCTs have very fragile results
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
The Fragility Index in Hand Surgery Randomized Controlled Trials
J Hand Surg Am. 2019;44(8):698. doi: 10.1016/j.jhsa.2018.10.005. Epub 2018 Nov 9Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
The Fragility Index is an important concept when assessing the strength of findings from a positive RCT - essentially, the Fragility Index asks how many patients it would take with an opposite outcome in order for the overall trial results to become non-significant. In this paper, the authors apply this concept to RCTs in hand surgery. They include 5 RCTs with positive findings on a dichotomous pr...
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